Two-Stage Optimization Method for the Bearing Layout of Isolated Structure by Yu Dang, GenXiong Zhao, HongTu Tian, Guobao Li

“…The isolation devices are simplified as a kind of lead-rubber bearing. The genetic algorithm is used to find the optimal parameters of the isolated layer. …”
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Membrane-targeted push-pull azobenzenes for the optical modulation of membrane potential by Valentina Sesti, Arianna Magni, Matteo Moschetta, Chiara Florindi, Marlene E. Pfeffer, Mattia Lorenzo DiFrancesco, Michele Guizzardi, Giulia Folpini, Luca Sala, Alessandra Gilda Ritacca, Beatrice Campanelli, Paola Moretti, Giuseppe Maria Paternò, Luca Maragliano, Matteo Tommasini, Francesco Lodola, Elisabetta Colombo, Fabio Benfenati, Chiara Bertarelli, Guglielmo Lanzani

“…We anticipate the MTs approach to find applications in neuroscience, biomedicine, and biophotonics, providing a tool for modulating cell physiology without genetic interventions.…”
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Blue elixir of youth and wellness: The multicomponent-multitarget paradigm of Curcuma caesia Roxb by Sabrina Burattini, Federico Gianfanti, Francesco Onesimo, Sabrina Donati Zeppa, Barbara Canonico, Mariele Montanari, Giovanna Panza, Daniele Lopez, Giosuè Annibalini, Fabiana Fanelli, Roberta Saltarelli, Michele Mari, Michele Retini, Riham Osman, Aghna Mariam, Matteo Micucci, Giovanni Caprioli, Agnese Santanatoglia, Deborah Agostini, Michela Battistelli

“…Aging is a complex biological process influenced by genetic, environmental, and lifestyle factors, including diet and exercise. …”
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Template switching during DNA replication is a prevalent source of adaptive gene amplification by Julie N Chuong, Nadav Ben Nun, Ina Suresh, Julia Cano Matthews, Titir De, Grace Avecilla, Farah Abdul-Rahman, Nathan Brandt, Yoav Ram, David Gresham

“…Copy number variants (CNVs) are an important source of genetic variation underlying rapid adaptation and genome evolution. …”
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Evaluation of the Effectiveness of Multiple Machine Learning Methods in Remote Sensing Quantitative Retrieval of Suspended Matter Concentrations: A Case Study of Nansi Lake in Nort... by Xiuyu Liu, Zhen Zhang, Tao Jiang, Xuehua Li, Yanyi Li

“…Then, seven methods such as linear regression, BP neural network (BP), KNN, random forest (RF), and random forest based on genetic algorithm optimization (GA_RF) are used to construct the inversion model of TSM concentration. …”
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Integrating MAPK pathway inhibition into standard-of-care therapy for pediatric low-grade glioma by Erin E. Crotty, Aimee A. Sato, Aimee A. Sato, Mohamed S. Abdelbaki

“…Pediatric low-grade gliomas (pLGG) are a group of tumors largely driven by alterations in a single genetic pathway, known as the RAS-RAF-mitogen-activated protein kinase (MAPK) pathway. …”
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Tree shrew as a new animal model for musculoskeletal disorders and aging by Xiaocui Wei, Honghao Li, Jingyang Qiu, Jianlin Jiao, Xiongtian Guo, Gaosheng Yin, Ping Yang, Yi Han, Qiongzhi Zhao, Hao Zeng, Zhi Rao, Xuefei Gao, Kai Li, Pinglin Lai, Sheng Zhang, Chengliang Yang, Di Lu, Xiaochun Bai

“…In this study, we investigated the potential suitability of the tree shrew, a small mammal with a close genetic relationship to primates, as a new animal model for MSDs. …”
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Rhipicephalus simus ticks: new hosts for phleboviruses by Samuel Munalula Munjita, Benjamin Mubemba, John Tembo, Mathew Bates, Sody Munsaka, Ala Tabor

“…Phylogenetic analysis positioned LSK-ZM-102022 in a distinct but lone lineage within tick phleboviruses basal to known species like brown dog tick phlebovirus and phlebovirus Antigone. Pair-wise genetic distance analysis revealed similar findings. …”
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Optimization of Irrigation and Fertilization in Maize–Soybean System Based on Coupled Water–Carbon–Nitrogen Interactions by Aizheng Yang, Shuyuan Luo, Yaowen Xu, Pingan Zhang, Zhenyi Sun, Kun Hu, Mo Li

“…A multi-objective optimization model, integrating experimental data and mechanistic insights, was constructed and refined using the NSGA-III genetic algorithm to identify the optimal water and nitrogen application ratios. …”
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Red Army Soldiers from Kalmykia in the Battles for Belarus: a Historical and Statistical Study by Sergey G. Ershov

“…When writing the article, a complex of various general scientific and special methods was used, including historical-genetic, historical-comparative, historical-typological, historical-systemic, and statistical methods. …”
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The Effect of IL-4 Gene Polymorphisms on Cytokine Production in Patients with Chronic Periodontitis and in Healthy Controls by Jirina Bartova, Petra Borilova Linhartova, Stepan Podzimek, Tatjana Janatova, Kazi Svobodova, Antonin Fassmann, Jana Duskova, Jaromir Belacek, Lydie Izakovicova Holla

“…Chronic periodontitis (CP) is an inflammatory disease of the teeth-supporting tissues in which genetic predisposition, dental plaque bacteria, and immune mechanisms all play important roles. …”
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Difference in nicotine metabolism as a potential factor causing disparities in tobacco consumption estimates by wastewater-based epidemiology by Min-Tz Weng, Kathryn J Steadman, Kelly Zhong, Maryam Al-Gharibeh, Qiuda Zheng, Phong K Thai

“…We hypothesise it could be partly related to genetic differences in CYP2A6 enzyme activity affecting COT and 3HC excretion. …”
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The SERPINB4 gene mutation identified in twin patients with Crohn’s disease impaires the intestinal epithelial cell functions by Xiao-Mei Ouyang, Jun-Hui Lin, Ying Lin, Xian-Ling Zhao, Ya‐Ni Huo, Lai-Ying Liang, Yong-Dong Huang, Gui-Jing Xie, Peng Mi, Zhen-Yu Ye, Bayasi Guleng

“…To identify new targets related to the initiation of CD, we screened a pair of twins with CD, which is a rare phenomenon in the Chinese population, for genetic susceptibility factors. Whole-exome sequencing (WES) of these patients revealed a mutation in their SERPINB4 gene. …”
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NIPAL1 as a prognostic biomarker associated with pancreatic adenocarcinoma progression and immune infiltration by Youlong Zhu, Zongze Qi, Shaoqi Zu, Fangchao Yang, Yanming Wang, Lei Zhu, Xintong Li, Ruixue Li, Hong Zhu

“…Abstract Pancreatic adenocarcinoma (PAAD) is a highly malignant tumor in the digestive system, with an increasing incidence and mortality rate globally. Recent genetic studies have revealed that the abnormal expression and functional dysregulation of various genes are involved in the occurrence and progression of pancreatic cancer. …”
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A Review on Biosurfactant Applications in the Petroleum Industry by Wei Xi, Yuanye Ping, Masoome Agha Alikhani

“…Biosurfactants are synthesized by microbes; therefore, various genetic diversities of microorganisms provide the considerable capability to produce new types of biosurfactants, which can develop EOR technology. …”
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G Protein-Coupled Receptor 17 Inhibits Glucagon-like Peptide-1 Secretion via a Gi/o-Dependent Mechanism in Enteroendocrine Cells by Jason M. Conley, Alexander Jochim, Carmella Evans-Molina, Val J. Watts, Hongxia Ren

“…Here, we expressed the human GPR17 long isoform (hGPR17L) in GLUTag cells, a murine EEC line, and we used the GPR17 synthetic agonist MDL29,951 together with pharmacological probes and genetic approaches to quantitatively assess the contribution of GPR17 signaling to GLP-1 secretion. …”
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Detection of Hemoglobinopathies in Cuban Pregnant Women from the Program: Sickle Cell Anemias in Cuba by Yadira Valdés Fraser, Tatiana Acosta Sánchez, Jacqueline Pérez Rodríguez, Beatriz Suárez Besil, Sandra Bárbara Correa Jiménez

“…The program provides genetic counseling, molecular prenatal diagnosis and selective interruptions of affected fetuses, at the re-quest of couples. …”
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Structures and strategies for retaining an international pediatric cohort from birth: Lessons from The Environmental Determinants of Diabetes in the Young (TEDDY) study by Patricia Gesualdo, Jessica Melin, Rachel Karban, Claire Crouch, Michael Killian, Diane Hopkins, Annika Adamsson, Joanna Stock, Suzanne Bennett Johnson, Judith Baxter

“…The aim of this report is to describe the structures and strategies used to retain participants in The Environmental Determinants of Diabetes in the Young (TEDDY) Study, an observational study of children at increased genetic risk for type 1 diabetes followed in an intensive protocol from birth until age 15. …”
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Genome-wide association study reveals major loci for resistance to septoria tritici blotch in a Tunisian durum wheat collection. by Maroua Ouaja, Bikash Ghimire, Bochra Amina Bahri, Medini Maher, Sahbi Ferjaoui, Sripada Udupa, Sonia Hamza

“…Tunisian durum wheat landraces are reported to be valuable genetic resources for resistance to STB and should prominently be deployed in breeding programs to develop new varieties resistant to STB disease. …”
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A 15-year pheochromocytoma and paraganglioma experience in a single centre: a Singapore perspective by Yingshan Lee, Leon Yuan Rui Tan, Shaikh Abdul Kader Kamaldeen Abdul Shakoor

“…Disease recurrences and metastasis occurred in up to one-fifth of the patients. Genetic screening should be offered to patients with PCC and PGL.…”
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