Bayesian polygenic risk estimation approach to nuclear families with discordant sib-pairs for myelomeningocele. by Adolfo Aguayo-Gómez, Leonora Luna-Muñoz, Yevgeniya Svyryd, Luis Ángel Muñoz-Téllez, Osvaldo M Mutchinick

“…In the present study, we aimed to investigate the genetic risk estimate for MMC in a cohort of 203 Mexican nuclear families with discordant siblings for the defect. …”
Get full text

Persistent Hyperinsulinemic Hypoglycemia in Iraqi Pediatric Population: A Single Tertiary Center Experience by Munib Ahmed Al-Zubaidi, Wasnaa Hadi Abdullah, Khalid Hatem Kareem

“…Patients who did not respond to diazoxide had higher mean insulin and age at presentation with 19.58 ± 17.28 µU/ml and 9.73 ± 28.23 months, respectively. Conclusion: While genetic study remains the gold standard for the diagnosis of CHI, clinical characteristics of patients can be the only helpful way to predict further management in countries with limited resources.…”
Get full text

Microscopic Analysis of Severe Structural Rearrangements of the Plant Endoplasmic Reticulum and Golgi Caused by Overexpression of Poa semilatent virus Movement Protein by Andrey G. Solovyev, Joachim Schiemann, Sergey Y. Morozov

Get full text

Application of the Logistics Management System Based on Cloud Computing Technology by Shuai Zhang

“…This paper analyzes the advantages of processing the real-time routing of distribution vehicles under the cloud computing mode and establishes the application service architecture of vehicle routing optimization in cold chain logistics; under this architecture, multisource real-time traffic information is obtained, the vehicle distribution time and comprehensive cost are analyzed, the vehicle routing optimization model of cold chain logistics distribution is constructed, and the coarse-grained parallel genetic algorithm is used to solve the model in the cloud computing environment. …”
Get full text

Smart Grid Dispatching Optimization for System Resilience Improvement by Li Liao, Chengjun Ji

“…The solution method of combinatorial optimization is analyzed, and the genetic optimization algorithm adopted in this paper is selected and discussed. …”
Get full text

“TRANSHUMANIZATION” OF MODERN EDUCATION by G. L. ILYIN

“…NBICS combine nanotechnology, biotechnology, IT, cognitive and social sciences, genetic engineering, stem cells, and cloning. These research areas converge and create a cumulative effect. …”
Get full text

Apricot cultivars approved for production in Chelyabinsk Province by F. M. Gasymov

Get full text

La ecología política en México ¿Dónde estamos y para dónde vamos? by Leticia Durand Smith, Fernanda Figueroa Díaz, Mauricio Genet Guzmán Chávez

Get full text

Impaired inflammatory resolution with severe SARS-CoV-2 infection in leptin knock out obese hamster by Ren-Di Jiang, Yun-Zhe Luo, Hao-Feng Lin, Xiao-Shuang Zheng, Wen-Tao Zeng, Mei-Qin Liu, Hao-Hao Deng, Qi Wang, Ya-Na Lai, Ying Chen, Zi-Shuo Guo, Ya Zeng, Qian-Chun Gong, Chen Qiu, Mei Dong, Xi Wang, Zi-Yi Wang, Li-Na Ji, Pan-Pan Hou, Qian Li, Xu-Rui Shen, Bei Li, Yun Gao, Ai-Hua Zhang, Ting-Ting Jiang, Ai-Min Shi, Peng Zhou, Xin-Hua Lin, Zi-Qing Deng, Jian-Min Li, Zheng-Li Shi

Get full text

Deep learning uncovers histological patterns of YAP1/TEAD activity related to disease aggressiveness in cancer patients by Benoit Schmauch, Vincent Cabeli, Omar Darwiche Domingues, Jean-Eudes Le Douget, Alexandra Hardy, Reda Belbahri, Charles Maussion, Alberto Romagnoni, Markus Eckstein, Florian Fuchs, Aurélie Swalduz, Sylvie Lantuejoul, Hugo Crochet, François Ghiringhelli, Valentin Derangere, Caroline Truntzer, Harvey Pass, Andre L. Moreira, Luis Chiriboga, Yuanning Zheng, Michael Ozawa, Brooke E. Howitt, Olivier Gevaert, Nicolas Girard, Elton Rexhepaj, Iris Valtingojer, Laurent Debussche, Emanuele de Rinaldis, Frank Nestle, Emmanuel Spanakis, Valeria R. Fantin, Eric Y. Durand, Marion Classe, Katharina Von Loga, Elodie Pronier, Matteo Cesaroni

Get full text

Spare Parts Inventory Optimization for Military Vehicles Using a Mixed Probability Distribution by Mojtaba Salehi, Mojtaba Omidvar, Shohreh Shariati

“…The meta-heuristic method based on the genetic algorithm has been applied to save the total costs. …”
Get full text

From the depths of the Java Trench: genomic analysis of Priestia flexa JT4 reveals bioprospecting and lycopene production potential by Ocky K. Radjasa, Ray Steven, Yosua Natanael, Husna Nugrahapraja, Septhy K. Radjasa, Tati Kristianti, Maelita R. Moeis, Joko P. Trinugroho, Haekal B. Suharya, Alfito O. Rachmatsyah, Ari Dwijayanti, Mutiara R. Putri, Charlie E. de Fretes, Zen L. Siallagan, Muhammad Fadli, Rafidha D. A. Opier, Jandinta D. Farahyah, Viana Rahmawati, Meirifa Rizanti, Zalfa Humaira, Ary S. Prihatmanto, Nugroho D. Hananto, R. Dwi Susanto, Agus Chahyadi, Elfahmi, Neil Priharto, Kamarisima, Fenny M. Dwivany

“…While numerous studies have delved into the microbial ecology and biological potential of the marine environment, exploration of genetically encoded, deep-sea sourced secondary metabolites remains scarce. …”
Get full text

European distribution and intramuscular pathogenicity of divergent lyssaviruses West Caucasian bat virus and Lleida bat lyssavirus by Stefania Leopardi, Laurent Dacheux, Jordi Serra-Cobo, Ágota Ábrahám, Branka Bajić, Hervé Bourhy, Szilárd-Lehel Bücs, Ivana Budinski, Martina Castellan, Petra Drzewniokova, Heliana Dundarova, Francesca Festa, Lauriane Kergoat, Maxime Leuchtmann, Marc López-Roig, Dominique Pontier, Maria Francesca Priore, Emmanuelle Robardet, Dino Scaravelli, Barbara Zecchin, Zsófia Lanszki, Tamás Görföl, Gábor Kemenesi, Paola De Benedictis

Get full text

Exploring the Genotype-Environment Interaction in Sugar Beet (Beta vulgaris L.) Genotypes for Optimal Selection by Mahdi Ramazi, Saeed Sadeghzadeh Hemayati, Heshmat Omidi, Amirmohammad Naji

“…These findings suggest that fluctuations in environmental conditions and genetic factors can impact genotype performance across diverse environments, leading to marked variations in root yield and white sugar yield among genotypes. …”
Get full text

Osteopenia Metabolomic Biomarkers for Early Warning of Osteoporosis by Jie Wang, Dandan Yan, Suna Wang, Aihua Zhao, Xuhong Hou, Xiaojiao Zheng, Jingyi Guo, Li Shen, Yuqian Bao, Wei Jia, Xiangtian Yu, Cheng Hu, Zhenlin Zhang

Get full text

First seroprevalence survey of bovine anaplasmosis: an emerging tick-borne disease in commercial livestock and dairy farms in Bangladesh by Md. Makshuder Rahman Zim, Nurnabi Ahmed, Mostak Ahmed, Md. Abu Haris Miah, Md. Mahfuzur Rahman Sajib, Md. Rajiur Rahaman Rabbi, Md. Khalilur Rahman, Babul Chandra Roy, Md. Hasanuzzaman Talukder, Ala Tabor

“…Study on the molecular epidemiology and genetic diversity of Anaplasma among cattle populations should be prioritized.…”
Get full text

Intelligent Time-Domain Parameters Matching for Shock Response Spectrum and Its Experimental Validation in Active Vibration Control Systems by Jinxin Liu, Liangdong Yang, Xingwu Zhang, Ruqiang Yan, Xuefeng Chen

“…A variable-weight method has been introduced to combine the effects of hundreds objective functions so that the optimization problem can be solved by using the genetic algorithm. The frequency response function of the shaking system has been taken into consideration in the calculation of the objective function, so the synthesized TSW can be applied directly to the SRS test. …”
Get full text

Testing of chickens experimentally infected with A/H9N2 avian influenza virus isolates for their immune responses by O. S. Osipova, M. A. Volkova, S. V. Frolov, D. B. Andreychuk, I. A. Chvala

“…Data on tests of chickens for their immune responses to infection with low pathogenic А/Н9N2 avian influenza virus isolates belonging to Y-280 and G1 genetic lines are presented in the paper. CD4⁺/CD8⁺ ratios were determined with flow cytometry for initial immune status examination and for detection of apparent immune system disorders. …”
Get full text

Current and Novel Therapies for Cluster Headache: A Narrative Review by Bruna de Freitas Dias, Christopher L. Robinson, Maria Dolores Villar-Martinez, Sait Ashina, Peter J. Goadsby

“…CH is characterized by intense unilateral pain and autonomic symptoms, significantly impacting patients’ quality of life, mental health, and productivity. Genetic associations suggest a familial risk for developing CH, with lifestyle factors also potentially playing a role. …”
Get full text

Understanding the properties and functional role of neutrophils in oral squamous cell carcinoma – A systematic review by Thayalan Dineshkumar, Nirmala Anandan, Krishnan Rajkumar, Indumathi N

“…Background: OSCC, the most prevalent type of oral cancer, is thought to be caused by genetic alterations and is more common in people who use tobacco products, alcohol, betel quid, and areca nuts. …”
Get full text