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12081
Improved production strain maintenance technique for Burkholderia mallei 5584 (Master seed) used for glander diagnostic agent production
Published 2024-03-01“…The previous strain maintenance technique involved its storage in its native state, which facilitated accumulation of genetic mutations and, ultimately modification of bacterial cell properties. …”
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12082
A lineage 1 branch porcine reproductive and respiratory syndrome virus live vaccine candidate provides broad cross-protection against HP-like PRRSV in piglets
Published 2025-12-01“…HP-PRRSV has undergone significant genetic variation following nearly two decades of evolution and has transformed into a subtype referred to as HP-like PRRSV, which also exhibits high pathogenicity. …”
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12083
An IS element-driven antisense RNA attenuates the expression of serotype 2 fimbriae and the cytotoxicity of Bordetella pertussis
Published 2025-12-01“…Insertion sequences (IS) represent mobile genetic elements that have been shown to be associated with bacterial evolution and adaptation due to their effects on genome plasticity. …”
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12084
Eight Years of Norovirus Surveillance in Urban Wastewater: Insights from Next-Generation
Published 2025-01-01“…In this study, wastewater-based epidemiology (WBE) was used to monitor the circulation and genetic diversity of HNoVs in Rome over an eight-year period (2017–2024). …”
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12085
Glioblastoma with Both Oligodendroglioma and Primitive Neuroectodermal Tumor-Like Components in a Case with 9-Year Survival
Published 2018-01-01“…Young age, aggressive surgical resection, and pathologic and genetic features may have contributed to the long-term survival of the patient.…”
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12086
High Efficiency Direct Shoot Organogenesis from Leaf Segments of Aerva lanata (L.) Juss. Ex Schult by Using Thidiazuron
Published 2014-01-01“…Furthermore, this protocol may be used for a large scale production of its medicinally active compounds and genetic transformations for further improvement.…”
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12087
Targeted Regulation Of Cgrp Gene Expression
Published 2001-01-01“…This observation supports the importance of a finely tuned balance of calcium in the trigeminal neuron, which is intriguing in light of genetic evidence for calcium channel mutations in a rare form of inherited migraine. …”
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12088
Drought Tolerance in Modern and Wild Wheat
Published 2013-01-01“…Drought tolerance is crucial to stabilize and increase food production since domestication has limited the genetic diversity of crops including wild wheat, leading to cultivated species, adapted to artificial environments, and lost tolerance to drought stress. …”
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12089
Neutral drift upon threshold-like selection promotes variation in antibiotic resistance phenotype
Published 2024-12-01“…Mechanisms that can explain genetic diversity by describing connections between genotype and organismal fitness have been described. …”
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12090
Fate and long-lasting therapeutic effects of mesenchymal stromal/stem-like cells: mechanistic insights
Published 2025-02-01“…Recent studies have provided evidence that the uptake of ABs with a distinct genetic component can induce changes in gene expression through the process of epigenetic remodeling. …”
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12091
Translational regulation of PKD1 by evolutionarily conserved upstream open reading frames
Published 2025-12-01“…Mutations in PKD1 coding sequence and abnormal PKD1 expression levels contribute to the development of autosomal-dominant polycystic kidney disease, the most common genetic disorder. Regulation of PKD1 expression by factors located in the promoter and 3´ UTR have been extensively studied. …”
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12092
Influence of particle size on NIR spectroscopic characterization of sorghum biomass for the biofuel industry
Published 2025-01-01“…Grown under field conditions, a total of 113 types of genetically diverse sorghum accessions were dried, ground, and sieved (<250, 250–600, 600–850, and > 850 µm particle size) for developing partial least square regression (PLSR) prediction models for moisture, ash, extractive, glucan, xylan, acid-soluble lignin (ASL), acid-insoluble lignin (AIL), and total lignin (ASL + AIL). …”
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12093
Genomic, Evolutionary, and Pathogenic Characterization of a New <i>Polerovirus</i> in Traditional Chinese Medicine <i>Viola philippica</i>
Published 2025-01-01“…Two potential recombination events were identified within ORF2, ORF3a, and ORF3, providing insights into the genetic diversity and evolution history of this novel polerovirus. …”
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12094
Evidence that a STAT3 Mutation Causing Hyper IgE Syndrome Leads to Repression of Transcriptional Activity
Published 2019-01-01“…Th17 cell phenotyping revealed low levels of IL-17 expressing cells (0.3% of total CD4 T Cells numbers). Genetic analysis identified a missense mutation, N567D, in a conserved region of the linker domain of STAT3. …”
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12095
A New Metaheuristic-Based Hierarchical Clustering Algorithm for Software Modularization
Published 2020-01-01“…Due to the NP hardness of the clustering problem, evolutionary approaches such as the genetic algorithm have been used to solve this problem. …”
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12096
Three decades of research efforts on the uses, conservation, and management of Cola nitida (Vent.): State of knowledge and prospects in Africa
Published 2024-12-01“…Several studies were focused on the socio-economic importance of the species (n = 139 ~ 50%), nutritional and chemical properties of its organs (n = 48 ~ 17%), improvement of its propagation methods (n = 30 ~ 11%), pest and pesticide control (n = 39 ~ 14%), morphological and genetic diversity (n = 21 ~ 7.5%), its botanical description and ecology (n = 2 ~ 0.7%), and climate change threats on the species (n = 1 ~ 0.3%). …”
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12097
Prognostic factors in hereditary breast cancer: A review
Published 2024-08-01“…The response to chemotherapy, especially platinum-based drugs, is influenced by genetic mutations such as TP53 and PTEN, which are common in TNBC. …”
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12098
Comparative analysis of selected methods of carbapenemase determination among clinical Klebsiella pneumoniae.
Published 2025-01-01“…The production of carbapenemases was assessed using phenotypic and genetic methods. The strains tested showed complete resistance to most beta-lactams and varying sensitivity to drugs from the quinolone carbapenem group and aminoglycosides. …”
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12099
A Case of Noncompaction at All Segments of Both Right and Left Ventricles
Published 2014-01-01“…Extensive sinusoid formation and trabeculation of RV and nearby all LV segments and its association with mental retardation suggest presence of strong genetic background.…”
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12100
Single Nucleotide Polymorphisms in IFN-γ Signaling Pathway Associated with Risk of Hepatitis B Virus Infection in Chinese Children
Published 2020-01-01“…Our study confirmed that genetic variants in IFN-γ signaling pathway have significant associations with HBV infection, especially with HBV breakthrough in children. …”
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