Differences in the genomic profiles of cell‐free DNA between plasma, sputum, urine, and tumor tissue in advanced NSCLC by Zhen Wu, Zhen Yang, Chun Sun Li, Wei Zhao, Zhi Xin Liang, Yu Dai, Qiang Zhu, Kai Ling Miao, Dong Hua Cui, Liang An Chen

“…A prospective study was performed to detect differences in genetic profiles of cfDNA in sputum, plasma, urine, and tumor tissue from 50 advanced NSCLC patients in parallel by the same next‐generation sequencing (NGS) platform. …”
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siRNA therapeutics for effective management of rheumatoid arthritis by Vishakha R. Chakole, Tathagata Dutta, Priyankar Sen

“…This property makes siRNA a valuable tool for developing RNAi therapeutics, particularly for managing conditions like osteoporosis, cancer, genetic disorders, and autoimmune disorders. Rheumatoid arthritis (RA) is a significant autoimmune disorder. …”
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Mineral Composition and Baking Value of the Winter Wheat Grain under Varied Environmental and Agronomic Conditions by Iwona Jaskulska, Dariusz Jaskulski, Lech Gałęzewski, Tomasz Knapowski, Wojciech Kozera, Roman Wacławowicz

“…Opal cultivar grain of the genetically determined prime-quality wheat was obtained in a two-year field experiment (varied soil and weather). …”
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The creative history of Naki Isanbet’s comedy “Red-haired chichyan and Black-haired beauty” by Zamaletdinov R.R., Khabutdinova M.M.

“…The study was conducted using genetic, cultural-historical, and comparative research methods, the choice of which is determined by the nature of the analyzed text. …”
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Combination of Artificial Neural Network and Particle Swarm Intelligence Algorithm for Diagnosing Diabetes by Cillian Thompson, Oscar Higgins

“…Diabetes is one of the challenges of today's society, which is influenced by important factors such as nutrition, obesity, physical inactivity, and genetic background. Early diagnosis of diabetes reduces the effects of this destructive disease. …”
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FlashTag-mediated Labeling for Intraventricular Macrophages in the Embryonic Brain by Hisa Asai, Mizuki Ono, Takaki Miyata, Yuki Hattori

“…Various methods are used in fate mapping, including dye injections, genetic labeling (e.g., Cre-lox recombination systems), and molecular markers to label cells and track their progeny. …”
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The Potential Use of the CRISPR-Cas System for HIV-1 Gene Therapy by Gabriela De Nardi Sanches-da-Silva, Luiza Fonseca Sales Medeiros, Fabio Mitsuo Lima

“…The CRISPR- (clustered regularly interspaced short palindromic repeat-) Cas system is a genome-editing method which uses a guide RNA, a complementary sequence to the interested site, recruiting a nuclease that can break the viral or the host cell genetic material. From this double-stranded break, cellular repair mechanisms are activated being able to generate deletions, insertions, or substitutions, in order to inactivate specific gene loci, leading to loss of function. …”
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Immune dynamics throughout life in relation to sex hormones and perspectives gained from gender-affirming hormone therapy by Ahmet Yalcinkaya, Ahmet Yalcinkaya, Rumeysa Yalcinkaya, Fabian Sardh, Fabian Sardh, Nils Landegren, Nils Landegren

“…These differences are influenced by hormonal, genetic, and environmental factors, and vary throughout life stages. …”
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A High-Quality Phased Genome Assembly of Stinging Nettle (<i>Urtica dioica</i> ssp. <i>dioica</i>) by Kaede Hirabayashi, Christopher R. Dumigan, Matúš Kučka, Diana M. Percy, Gea Guerriero, Quentin Cronk, Michael K. Deyholos, Marco Todesco

“…This genome assembly represents an important resource for the nettle community and will enable the investigation of the genetic basis of the many interesting characteristics of this species.…”
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Macrophages overexpressing interleukin‐10 target and prevent atherosclerosis: Regression of plaque formation and reduction in necrotic core by Mingyi Wang, Shanshan Zhou, Yingyun Hu, Wei Tong, Hao Zhou, Mingrui Ma, Xingxuan Cai, Zhengbin Zhang, Luo Zhang, Yundai Chen

“…In this study, we aimed to investigate the effectiveness of an approach designed to overexpress IL‐10 in macrophages and subsequently introduce these genetically modified cells into ApoE−/− mice to promote atherosclerosis regression. …”
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Protective Effects of Garlic and Cinnamon Oils on Hepatocellular Carcinoma in Albino Rats by Salah M. Aly, Hamdy A. Fetaih, Abeer A. I. Hassanin, Mosleh M. Abomughaid, Aliaa A. Ismail

“…The HCC-induced group showed a significant decrease in the body mass and a significant elevation in the liver weight, alpha-fetoprotein (AFP), liver enzymes, hepatic malondialdehyde (MDA), and p53 protein expression levels as well as genetic mutations in intron 5 of p53 gene in the form of Single-Nucleotide Polymorphisms (SNPs) and insertions. …”
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Generation of bovine decellularized testicular bio-scaffolds as a 3D platform for testis bioengineering by Francesca Di Filippo, Tiziana A. L. Brevini, Georgia Pennarossa, Fulvio Gandolfi

“…Accelerating the genetic selection to obtain animals more resilient to climate changes, and with a lower environmental impact, would greatly benefit by a substantial shortening of the generation interval. …”
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Ship Formation and Route Optimization Design Based on Improved PSO and D-P Algorithm by Peilong Xu, Dan Lan, Haolin Yang, Shengtian Zhang, Hyeonseok Kim, Incheol Shin

“…The particle swarm algorithm introduces dynamic adaptive parameter adjustment and the cross mutation strategy of genetic algorithm, while the Douglas-Peucker algorithm integrates density-based noise application spatial clustering algorithm to improve model performance. …”
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Lemongrass (Cymbopogon citratus) Essential Oil: Extraction, Composition, Bioactivity and Uses for Food Preservation – a Review by Ewa Majewska, Mariola Kozłowska, Eliza Gruczyńska-Sękowska, Dorota Kowalska, Katarzyna Tarnowska

“…The chemical composition of the essential oil of C. citratus varies according to the geographical origin, farming practices, plant age, photoperiod, harvest period, genetic differences, and extraction methods. The chemical constituents of the essential oil which have constantly been detected and determine its biological activity are aldehydes, hydrocarbon terpenes, alcohols, ketones, and esters. …”
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In the coevolution of cotton and pathogenic fungi, resistant cotton varieties lead to an escalation in the virulence of Verticillium dahliae by Yalin Zhang, Lifang Cui, Ruibing Liu, Zili Feng, Hongjie Feng, Jinglong Zhou, Lihong Zhao, Feng Wei, Heqin Zhu

“…Consequently, among the offspring strains, high virulence strains exhibited higher levels of physiological characteristics and genetic diversity compared to moderate and low virulence strains. …”
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Elevated ALOX12 in renal tissue predicts progression in diabetic kidney disease by Meixi Wang, Jingjing Wang, Jinni Wang, Yonggui Wu, Xiangming Qi

“…The present study sequenced db/m mouse and db/db mouse to determine the ALOX12 genetic changes related to DKD. After preliminary validation, ALOX12 levels were significantly elevated in the blood of DKD patients, but not during disease progression. …”
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Targeting S100A9 attenuates social dysfunction by modulating neuroinflammation and myelination in a mouse model of autism by Hong Gong, Yao Lu, Shi-Long Deng, Ke-Yi Lv, Jing Luo, Yi Luo, Zhu-Lin Du, Ling-Feng Wu, Tian-Yao Liu, Xia-Qing Wang, Jing-Hui Zhao, Lian Wang, Mei-Ling Xia, Dong-Mei Zhu, Li-Wei Wang, Xiao-Tang Fan

“…A combination of behavioral, pharmacological, immunological, genetic, molecular, and transcriptomics approaches were used to uncover the potential role of S100A9 in autism. …”
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Nature of viruses and the radical change in viral taxonomy by V. V. Makarov, L. P. Buchatsky

“…In this regard, the International Committee on the Taxonomy of Viruses (ICTV) changed the previous Code of their classification hierarchy from five ranks to a fifteen-rank one, that emulates a Linnaean framework and accommodates the entire spectrum of genetic divergence in the virosphere. Changes in the rank hierarchy are based on the evolution of the recognition of virus taxa over time, from a traditional phenotype-based characterization process to a multistage process that includes comparative sequence analyses of conserved genes and proteins, including gene phylogeny, gene synteny and shared gene content. …”
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Detection of COVID-19 Using Protein Sequence Data via Machine Learning Classification Approach by Siti Aminah, Gianinna Ardaneswari, Mufarrido Husnah, Ghani Deori, Handi Bagus Prasetyo

“…To optimize performance, we employed machine learning classification algorithms such as K-nearest neighbor (KNN), XGBoost, and Naïve Bayes, along with feature selection techniques like genetic algorithm (GA), LASSO, and support vector machine recursive feature elimination (SVM-RFE). …”
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Prospects of Using Microbiota Correction Methods in the Treatment of Inflammatory Bowel Disease by A. I. Akinshina, D. V. Smirnova, A. V. Zagainova, V. V. Makarov, S. M. Yudin

“…In recent years, preference has been given to more accurate and faster molecular genetic methods allowing a more detailed study of the key mechanisms by which microbiota affects the intestine in Crohn’s disease (CD) and ulcerative colitis (UC), as well as of the effect of microbial metabolites on their pathogenesis. …”
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