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1181
Combination of Artificial Neural Network and Particle Swarm Intelligence Algorithm for Diagnosing Diabetes
Published 2024-03-01“…Diabetes is one of the challenges of today's society, which is influenced by important factors such as nutrition, obesity, physical inactivity, and genetic background. Early diagnosis of diabetes reduces the effects of this destructive disease. …”
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1182
FlashTag-mediated Labeling for Intraventricular Macrophages in the Embryonic Brain
Published 2025-01-01“…Various methods are used in fate mapping, including dye injections, genetic labeling (e.g., Cre-lox recombination systems), and molecular markers to label cells and track their progeny. …”
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1183
In the coevolution of cotton and pathogenic fungi, resistant cotton varieties lead to an escalation in the virulence of Verticillium dahliae
Published 2025-01-01“…Consequently, among the offspring strains, high virulence strains exhibited higher levels of physiological characteristics and genetic diversity compared to moderate and low virulence strains. …”
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1184
Prospects of Using Microbiota Correction Methods in the Treatment of Inflammatory Bowel Disease
Published 2019-05-01“…In recent years, preference has been given to more accurate and faster molecular genetic methods allowing a more detailed study of the key mechanisms by which microbiota affects the intestine in Crohn’s disease (CD) and ulcerative colitis (UC), as well as of the effect of microbial metabolites on their pathogenesis. …”
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1185
A Survey of Nature-Inspired Meta-Heuristic Algorithms in Network Alignment
Published 2024-09-01“…It explores a wide range of nature-inspired algorithms, including genetic algorithms, particle swarm optimization, ant colony optimization, and simulated annealing. …”
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1186
Identification of mitochondrial carrier homolog 2 as an important therapeutic target of castration-resistant prostate cancer
Published 2025-02-01“…MTCH2 is also upregulated in locally treated CRPC tissue and various primary human CRPC cells. Using genetic silencing via shRNA and knockout (KO) through the CRISPR-sgRNA approach, we showed that the depletion of MTCH2 impaired mitochondrial function, resulting in a reduced oxygen consumption rate, diminished complex I activity, and decreased ATP levels, mitochondrial depolarization, and increased reactive oxygen species production in primary CRPC cells. …”
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1187
PARP Inhibitors in the Treatment of Ovarian Cancer
Published 2025-02-01“…Summary PARP inhibitors represent a significant advancement in ovarian cancer treatment, offering improved survival outcomes for patients with specific genetic profiles. Their integration into standard care protocols underscores their importance and efficacy, providing valuable therapeutic options in the fight against ovarian cancer. …”
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1188
The Anthropocene and the biodiversity crisis: an eco-evolutionary perspective
Published 2025-01-01“…This crisis does not only affect the ecological dynamics of biodiversity, but also its evolutionary dynamics, including genetic diversity, an aspect that is generally neglected. …”
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1189
Fate and long-lasting therapeutic effects of mesenchymal stromal/stem-like cells: mechanistic insights
Published 2025-02-01“…Recent studies have provided evidence that the uptake of ABs with a distinct genetic component can induce changes in gene expression through the process of epigenetic remodeling. …”
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1190
Mendelian randomization study of serum uric acid levels and urate-lowering drugs on pulmonary arterial hypertension outcomes
Published 2025-02-01“…This study establishes a genetic basis for a causal link between serum uric acid levels and PAH. …”
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1191
Identification of quantitative trait loci for yield traits and fine-mapping of qGW4 using the chromosome segment substitution line-Z708 and dissected single-segment substitution li...
Published 2025-02-01“…Here, a wide-grain rice chromosome segment substitution line (CSSL), Z708, carrying four substitution segments from Jinhui35 in the genetic background of Xihui18, was used to identify the QTL associated with grain size. …”
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1192
Probiogenomic analysis of Limosilactobacillus fermentum SD7, a probiotic candidate with remarkable aggregation abilities
Published 2025-02-01“…These findings provide a comprehensive understanding of the genetic composition of L. fermentum and its potential probiotic properties, identifying L. fermentum SD7 as a promising probiotic candidate for use in the food and healthcare industries.…”
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1193
Introducing a Markov Chain-Based Energy Awareness Approach for Cloud Data Center Virtual Machine Dynamic Management
Published 2024-12-01“…The approach integrates genetic algorithms and refrigeration simulation into the migration replacement process, leveraging absorbing Markov chains for predictive analysis. …”
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1194
Discrete vulnerability to pharmacological CDK2 inhibition is governed by heterogeneity of the cancer cell cycle
Published 2025-02-01“…In cancer models that are genetically independent of CDK2, pharmacological inhibitors suppress cell proliferation by inducing 4N cell cycle arrest and increasing the expressions of phospho-CDK1 (Y15) and cyclin B1. …”
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1195
Occurrence of macrolides resistance in Legionella pneumophila ST188: Results of the Belgian epidemiology and resistome investigation of clinical isolates
Published 2025-04-01“…Genotypic screening identified a 23S ribosomal RNA mutation linked to a high-level macrolide resistance in one isolate of ST188, which is genetically closed to resistant isolates from France. …”
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1196
Another new karst-dwelling rock gecko in the Cnemaspis siamensis group (Reptilia, Gekkonidae) from Kanchanaburi Province, western Thailand
Published 2025-02-01“…Phylogenetically, the new species is recovered as the sister taxon to C. huaseesom, but the two species are separated by 8.3–9.4% uncorrected pairwise genetic divergences in the mitochondrial NADH dehydrogenase subunit 2 gene and flanking tRNAs.…”
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1197
Case report: A novel 11-bp deletion in exon 11 causing a frameshift in the C-terminal of the ALAS2 gene leading to X-linked sideroblastic anemia—a family study
Published 2025-02-01“…X-linked sideroblastic anemia (XLSA) (MIM 300752) is the most common genetic form of sideroblastic anemia, a heterogeneous group of disorders characterized by iron deposits in the mitochondria of erythroid precursors. …”
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1198
Security protection method based on mimic defense and Paillier encryption for smart IoT terminals
Published 2024-12-01“…First, a security architecture was constructed based on the mimic defense theory to ensure the reliability and robustness of the system even when the edge domain smart terminal had its own security genetic defects. Then, a secure blind signature with Paillier encryption (SBSPE) algorithm was designed in this architecture to safeguard the data and privacy of the edge-area smart terminals throughout the data processing lifecycle of edge-area smart terminals. …”
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1199
Early Permian to Middle Triassic Formation petroleum potentials of Sydney Basin, Australia: A geochemical analysis
Published 2025-02-01“…Still, the molecular signature of some of the coal samples shows prokaryotic organic matter present in the extracts, indicating a thin section of possibly a calcareous lithology interbedded within the coal measure formation. Genetically, the coal extracts of the Permian in the Sydney Basin, Australia, provide a new insight into the generation and expulsion of oil from coal, which might be responsible for the widespread oil and gas shows in the basin. …”
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1200
Establishment and characterization of ovarian clear cell carcinoma patient-derived xenografts
Published 2025-02-01“…Patient-derived xenografts (PDX) are widely used in vivo models because of their supposedly accurate morphologic and (epi)genetic representation of patient tumors. Here, we established five subcutaneous OCCC PDXs. …”
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