Monkeypox and other orthopoxvirus zoonoses by K. N. Gruzdev

“…Along with this, there is a genetic transformation of pathogens. In this regard, the risks of human infection with orthopoxviruses of zoonotic nature are increasing. …”
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Landslide Forecasting Model Based on PCA and Improved CS-RBF by WANG Lianxia, LI Limin, FANG Zihao, REN Ruibin, FU Zhentao, CUI Chengtao

“…Various models including back propagation (BP), RBF, genetic algorithm-RBF (GA-RBF), CS-RBF, and others are compared with the improved CS-RBF model through experimental analysis. …”
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Sickle Cell Disease Activates Peripheral Blood Mononuclear Cells to Induce Cathepsins K and V Activity in Endothelial Cells by Philip M. Keegan, Sindhuja Surapaneni, Manu O. Platt

“…Sickle cell disease is a genetic disease that increases systemic inflammation as well as the risk of pediatric strokes, but links between sickle-induced inflammation and arterial remodeling are not clear. …”
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Comparison of the Infectivity and Transmission of Contemporary Canine and Equine H3N8 Influenza Viruses in Dogs by Heidi L. Pecoraro, Susi Bennett, Kristina Garretson, Ayshea M. Quintana, Katharine F. Lunn, Gabriele A. Landolt

“…Phylogenetic analyses indicate that canine influenza viruses (CIVs) (H3N8) evolved from contemporary equine influenza virus (EIV). Despite the genetic relatedness of EIV and CIV, recent evidence suggests that CIV is unable to infect, replicate, and spread among susceptible horses. …”
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Post-Translational Modifications of Proteins Orchestrate All Hallmarks of Cancer by Pathea Shawnae Bruno, Aneeta Arshad, Maria-Raluca Gogu, Natalie Waterman, Rylie Flack, Kimberly Dunn, Costel C. Darie, Anca-Narcisa Neagu

“…In this review, we summarized and analyzed a wide spectrum of PTMs of proteins involved in all regulatory mechanisms that drive tumorigenesis, genetic instability, epigenetic reprogramming, all events of the metastatic cascade, cytoskeleton and extracellular matrix (ECM) remodeling, angiogenesis, immune response, tumor-associated microbiome, and metabolism rewiring as the most important hallmarks of cancer. …”
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Analysis of the Complete Genomes of Enterovirus 71 Subtypes in China by Lei Wang, Yuzhu Dai, Jun Cheng, Changgui Sun, Yu Chen, Dawei Cui

“…The phylogenetic trees were developed by MEGA7.0 software, and the complete genetic epidemiological characteristics and amino acid mutations of EV-A71 from China were also analysed. …”
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Perspectives of K. pneumoniae’s zoonotic potential from wild birds to human by Cocoș I. Daiana, Mihai Folescu, Razvan T. Pătrînjan, Larisa Ardelean, Romeo T. Cristina

“…Research across various regions demonstrates the prevalence of antimicrobial resistance (AMR) Klebsiella pneumoniae in wild birds, with notable findings including the detection of carbapenemase-producing strains (K. pneumoniae carbapenemase, KPC) in gulls from Spain and Ukraine, and colistin-resistance genes (mcr-1 and mcr-2) in Egyptian migratory waterfowl. Genetic overlaps were observed between avian isolates and human clinical strains, such as indistinguishable K. pneumoniae genomes from grey-crowned cranes in Rwanda and human cases. …”
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Thymosin β4 Improves Differentiation and Vascularization of EHTs by Tilman Ziegler, Rabea Hinkel, Andrea Stöhr, Thomas Eschenhagen, Karl-Ludwig Laugwitz, Ferdinand le Noble, Robert David, Arne Hansen, Christian Kupatt

“…Finally, utilizing Tβ4-transduced EHTs generated from mice genetically engineered to label endothelial cells in vitro, we show that treatment with Tβ4 promotes vascularization and contractility in EHTs, highlighting Tβ4 as a growth factor improving the formation of cardiomyocytes from iPSC and enhancing the performance of EHTs generated from neonatal cardiomyocytes.…”
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An Integrated Method for Selecting Architecture Alternatives and Reconfiguration Options Towards System-of-Systems Resilience by Zhemei Fang, Hang Li, Dazhi Chen

“…After developing an SoS effectiveness evaluator, the method constructs an integrated multi-objective formulation for the initial architecture selection and reconfiguration process, and provides a solution algorithm based on a fast non-dominated sorting genetic algorithm. An application to an air and missile defense SoS illustrates the effectiveness of the proposed method. …”
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Canine parvovirus enteritis: epidemic situation analysis and perspectives by T. S. Galkina, A. К. Karaulov

“…One of the main biological properties of parvovirus is its continuous genetic evolution, which led to the replacement of the original virus type by new antigenic variants – CPV-2a, CPV-2b and CPV-2c. …”
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MABC: Power-Based Location Planning with a Modified ABC Algorithm for 5G Networks by Ruchi Sachan, Zahid Muhammad, Jaehoon (Paul) Jeong, Chang Wook Ahn, Hee Yong Youn

“…To estimate the optimal configuration of BSes and reduce the power requirement of connected UEs, we enhanced the ABC algorithm, which is named a Modified ABC (MABC) algorithm, and compared it with the latest work on Real-Coded Genetic Algorithm (RCGA) and Differential Evolution (DE) algorithm. …”
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Clinical studies with drugs and biologics aimed at slowing or reversing normal aging processes—emerging results and future perspectives by Ricardo P. Garay

“…In the future, attempts could be made to improve potency through a precondition or genetic modification of naive bone marrow stem cells. …”
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Incretin-responsive human pancreatic adipose tissue organoids: A functional model for fatty pancreas research by E. Lorza-Gil, O.D. Strauss, E. Ziegler, K. Kansy, M.-T. Katschke, G. Rahimi, D. Neuscheler, L. Sandforth, A. Sandforth, G. Sancar, B. Kaufmann, D. Hartmann, S. Singer, A.L. Mihaljevic, R. Jumpertz-von Schwartzenberg, J. Sbierski-Kind, T.D. Müller, A.L. Birkenfeld, F. Gerst

“…Objective: Infiltration of adipocytes into the pancreatic parenchyma has been linked to impaired insulin secretion in individuals with increased genetic risk of T2D and prediabetic conditions. However, the study of this ectopic fat depot has been limited by the lack of suitable in vitro models. …”
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Successful Oocyte Retrieval, Fertilization, and Clinical Pregnancy with Low Serum β-hCG on the Day of Oocyte Collection: A Reappraisal of the Definition of the Empty Follicle Syndr... by Nicole A. Van De Velde, Charalampos Chatzicharalampous, Awoniyi O. Awonuga

“…Of these, eight embryos survived to day 5 and were subjected to preimplantation genetic screening (PGS) by comparative genomic hybridization (CGH). …”
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Carbonic anhydrase 2-derived drug-responsive domain regulates membrane-bound cytokine expression and function in engineered T cells by Mara C. Inniss, Sean G. Smith, Dan Jun Li, Benjamin Primack, Dexue Sun, Grace Y. Olinger, Kerri-Lynn Sheahan, Theresa Ross, Meghan Langley, Violet Young, Andres Alvarado, Shabnam Davoodi, Jiefei Geng, Michael Schebesta, Michelle L. Ols, Jeremy Tchaicha, Jan ter Meulen, Dhruv K. Sethi

“…Using protein-engineering solutions to increase the valency of DRDs fused to the cargo we have developed “modulation hubs” and show tight regulation of membrane-bound cytokines IL2, IL12, IL15, IL21, IL23, and IFNα in genetically engineered T cells. Finally, CA2-DRD regulated IL12 mediates regulated efficacy in a solid tumor model. …”
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Intraspecific Crossability in Andrographis paniculata Nees: A Barrier against Breeding of the Species by Alireza Valdiani, Mihdzar Abdul Kadir, Mohd Said Saad, Daryush Talei, Vahid Omidvar, Chia Sok Hua

“…Despite all the mentioned contrivances, we still believe that a genetic incongruity should be involved as an additional obstacle in crossability of those combinations that failed or responded deficiently to outcrossing.…”
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Reservoir characteristics and distribution of the Majiagou Formation in the Fuxian area of Ordos Basin, China by Ning Gu, Juntao Zhang, Xiaohui Jin, Jiaqi Yang, Fei Yang, Lu Liu

“…Through analyses of mineralogy, petrology, and reservoir geology, three major types of dolomite reservoirs with different genetic mechanisms, including anhydritic moldic-dissolved pore type, dolomitic intercrystalline-pore type, and fractured type were identified, and their formation mechanisms and distribution patterns were examined. …”
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Untargeted metabolomics of Aloe volatiles: Implications in pathway enrichments for improved bioactivities by Nehal Batra, Priyankar Dey

“…Enhancing the production of economically and medically important plant metabolites by genetic and metabolic manipulation is a lucrative approach for enhancing crop quality. …”
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A Versatile Method to Create Antibody/Split‐Enzyme Complexes and Its Application to a Rapid, Homogeneous, and Universal Electrochemical Immunosensing System by Yuka Tobita, Kensuke Hirano, Daimei Miura, Yuma Hatano, Wakako Tsugawa, Kazunori Ikebukuro, Koji Sode, Ryutaro Asano

“…Abstract In this study, a versatile method is developed to create an antibody/split‐enzyme complex for use in electrochemical immunosensors. SpyCatchers are genetically fused at each terminus of flavin adenine dinucleotide‐dependent glucose dehydrogenase (FAD‐GDH) and a protease recognition sequence is inserted into a loop region to prepare a soluble protein and the split GDH. …”
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Enterprise Network Marketing Prediction Using the Optimized GA-BP Neural Network by Ruyi Yang

“…Based on the analysis of the shortcomings of the traditional BP network, this paper uses a genetic algorithm with good global search capabilities to improve the neural network. …”
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