Participant Experiences in the Environmental Determinants of Diabetes in the Young Study: Common Reasons for Withdrawing by Barbro Lernmark, Kristian Lynch, Judith Baxter, Roswith Roth, Tuula Simell, Laura Smith, Ulrica Swartling, Suzanne Bennett Johnson, TEDDY Study Group

“…Results suggest that, for families of children genetically at risk for diabetes, procedures that can be painful/frightening should be used with caution. …”
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Optimal Location of Multiple Tuned Mass Dampers in Regular and Irregular Tall Steel Buildings Plan by Mohsen Khazaei, Reza Vahdani, Ali Kheyroddin

“…The SAP2000 API and MATLAB genetic algorithm are used to determine the optimal location of the MTMDs in the roof plans of the buildings. …”
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Looking outside the box with a pathology aware AI approach for analyzing OCT retinal images in Stargardt disease by Parisa Khateri, Tiana Koottungal, Damon Wong, Rupert W. Strauss, Lucas Janeschitz-Kriegl, Maximilian Pfau, Leopold Schmetterer, Hendrik P. N. Scholl

“…Abstract Stargardt disease type 1 (STGD1) is a genetic disorder that leads to progressive vision loss, with no approved treatments currently available. …”
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Macrophage-inherited exosome excise tumor immunosuppression to expedite immune-activated ferroptosis by Yan Liu, Junjie Liu, Qin Wang, Kun Zhang, Chunyan Zhu, Duo Wang, Guanhua Qiu, Xiaoqi Zhu, Chao Fang

“…M1 macrophage-derived exosomes can inherit more functions and genetic substances than nanovesicles since nanovesicles inevitably suffer from substance and function loss caused by extrusion-arised structural damage.Results Inspired by it, spontaneous homing to tumor and M2-like macrophage polarization into M1-like ones are attained, which not only significantly magnify oxidative stress but also mitigate ITM including M2-like macrophage polarization and regulatory T cell decrease, and regulate death pathways.Conclusions All these actions accomplish a synergistic antitumor enhancement against tumor progression, thus paving a general route to mitigate ITM, activate immune responses, and magnify ferroptosis.…”
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Diversity of Ethiopian Durum Wheat Landraces for Resistance to Stem Rust Seedling Resistance Genes by Silas Chiko, Mesfin Kebede Gessese, Daniel Shimelash, Wondimeneh Taye Haile, Belay Yebo Melo, Adera Sisay Wassie, Zemach Sorsa Lakore, Fentanesh Chekole Kassie

“…This study demonstrated the prevalence of significant genetic diversity for stem rust ASR genes in the Ethiopian durum wheat landraces.…”
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First report of the chloroplast and mitochondrial genomes of the Indian pitcher plant, Nepenthes khasiana Hook.f. by Ruchishree Konhar, Debasis Dash, Devendra Kumar Biswal

“…Despite the fact that it is a prominent insectivorous plant in the Nepenthaceae family, genomic resources for the species are limited, making genomic breeding and understanding the genetic basis of botanical carnivory difficult. Herein, we report the complete chloroplast (cp) and mitochondrial (mt) genomes of N. khasiana for the first time. …”
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Power Prioritization and Load Shedding in an Island with RESs Using ABC Algorithm by L. O. Mogaka, G. N. Nyakoe, M. J. Saulo

“…The results are then compared with those of Genetic Algorithm (GA), Particle Swarm Optimization (PSO), and GA-PSO hybrid. …”
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Deployment Optimization of Connected and Automated Vehicle Lanes with the Safety Benefits on Roadway Networks by Zhibo Gao, Zhizhou Wu, Wei Hao, Kejun Long

“…In addition, the upper level is the decision-making scheme of the lane deployment, while the lower level is the traffic assignment model including CAV and HV modes based on the decision-making scheme of the upper level. After that, a genetic algorithm was designed to solve the model. …”
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Balance Design and Optimization of Swing Force of the New Spatial 1T1R Parallel Mechanism by Wang Linping, Shen Huiping, Li Ju, Nie Yabiao, Chen Bingwei

“…Finally, considering the practical principle, further study the balance optimization of the pendulum force part, and use the genetic algorithm to obtain the optimal counterweight mass and counterweight position, and compare the balance before and after. …”
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Prevalence of CagA-positive Helicobacter pylori strain and H. pylori-associated gastritis activity in Tuva schoolchildren of different age groups by Tamara V. Polivanova, Vitaly A. Vshivkov

“…The received results demonstrate that development, course and progression of CagA-positive H. pylori associated gastritis is affected by genetic (ethnic) features of the host.…”
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Catalysts of change: Immunotherapy's frontier in oral oncology by Shyamaladevi Babu, Madhan Krishnan

“…These include risk factors such as tobacco use, alcohol intake, and infection with human papillomavirus (HPV), as well as genetic predispositions and environmental effects. …”
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Association of Interleukin-18 Gene Polymorphism with Susceptibility to Visceral Leishmaniasis in Endemic Area of Bihar, an Indian Population by Dinesh Kumar, Puja Tiwary, Jaya Chakravarty, Shyam Sundar

“…Interleukin-18 (IL-18) is a cytokine that mediates Th1 response by inducing interferon-gamma (IFN-γ) production in T cells and natural killer cells. Genetic polymorphisms in the IL-18 gene have been found to be associated with its expression in cancer, tuberculosis, HBV infection, and various other diseases. …”
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Complete genome sequence of Pseudomonas aeruginosa YK01, a sequence type 16 isolated from a patient with keratitis by Shuo Jiang, Mengmin Ye, Ke Liu, Huiluo Cao, Xiaoshan Lin

“…The complete reference genome of P. aeruginosa YK01 is expected to provide valuable data for investigating its genomic population, enhancing understanding of genetic basis of P. aeruginosa species complex. Data description A complete genome of 6.3 Mb was obtained for P. aeruginosa YK01 by combining Illumina 150-bp short reads and Nanopore long reads. …”
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The Efficacy and Mechanism of Chinese Herbal Medicine on Diabetic Kidney Disease by Zhenzhen Lu, Yifei Zhong, Wangyi Liu, Ling Xiang, Yueyi Deng

“…The etiology of DKD is very complicated and many factors are involved, such as genetic factors, hyperglycemia, hypertension, hyperlipidemia, abnormalities of renal hemodynamics, and metabolism of vasoactive substances. …”
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The protoplast two-way fusions and fusant characteristics of Antrodia cinnamomea and Cordyceps militaris by Wei-Kuang Lai, Yang-Chang Wu, Tai-Sheng Yeh, Chun-Ren Hsieh, Yi-Hong Tsai, Chien-Kei Wei, Chi-Ying Li, Ying-Chen Lu, Fang-Rong Chang

“…We selected each of two best-growing fused colonies Ac-Cm-1, Ac-Cm-2, Cm-Ac-1, and Cm-Ac-2, together with parental A. cinnamomea and C. militaris, and studied their morphology, growth antagonism tests, and genetic relationships by 18S rRNA sequencing. In comparison with the initial cultures of 4 fusants, the yields of adenosine, biomass, cordycepic acid, cordycepin, total polysaccharide, and total triterpenoids were increased up 1.305−50.1563 times in the optimal medium conditions. …”
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A Novel Association of Polymorphism in the ITGA4 Gene Encoding the VLA-4 α4 Subunit with Increased Risk of Alzheimer’s Disease by Vladimira Durmanova, Zuzana Parnicka, Juraj Javor, Gabriel Minarik, Lubomir Vrazda, Barbora Vaseckova, Karin Gmitterova, Maria Kralova, Jan Pecenak, Peter Filipcik, Ivana Shawkatova

“…The same study cohorts were also genotyped for the APOE-ε4, which is a known genetic factor associated with increased risk of AD developing. …”
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Cytokines and Myelination in the Central Nervous System by Thomas Schmitz, Li-Jin Chew

“…Experimental models that mimic human disease have been developed in order to study pathogenic and therapeutic mechanisms, but have shown mixed success in clinical application. However, genetically altered animals, and models of CNS inflammation and demyelination, have offered great insight into the complexities of neuroimmune interactions that impact oligodendrocyte function. …”
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Emission prediction and optimization of methanol/diesel dual-fuel engines based on ITransformer-BiGRU and NSGA-III by Mingzhang Pan, Xinxin Cao, Changcheng Fu, Shengyou Liao, Xiaorong Zhou, Wei Guan

“…Finally, based on the obtained mathematical model, the 3rd Non-dominated Sorting Genetic Algorithm (NGSA-III) is used to adjust and optimize the control parameters. …”
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Molecular Characterization of ESBL-Producing Enterobacteriaceae in Northern Portugal by Rúben Fernandes, Paula Amador, Carla Oliveira, Cristina Prudêncio

“…This study reports a high diversity of genetic patterns. Ten clusters were found for E. coli isolates and five clusters for K. pneumoniae strains by means of ERIC analysis. …”
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Asymmetric distribution of G-quadruplex forming sequences in genomes of retroviruses by Filip Kledus, Michaela Dobrovolná, Jean-Louis Mergny, Václav Brázda

“…These include the integration of endogenous retroviruses (ERVs) into host genomes, a process widely utilized in genetic engineering, and the ongoing search for HIV/AIDS treatment. …”
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