Inotersen to Treat Polyneuropathy Associated with Hereditary Transthyretin (hATTR) Amyloidosis by Christopher Robinson, Cynthia Pham, Alec M. Zamarripa, Chase S. Dugay, Christopher A. Lee, Amnon A. Berger, Avi Landman, Elyse M. Cornett, Hisham Kassem, Alan D. Kaye, Ivan Urits, Omar Viswanath, Latha Ganti

“…The use of RNA interference (RNAi) opens the door to the treatment of hereditary diseases by targeting them at the genetic level.…”
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Enhancing network lifetime in WSNs through coot algorithm-based energy management model by Namita Shinde, Dr. Vinod H․ Patil

“…This addresses issues such as high energy consumption, communication delays, and security.To ensure energy savings and network reliability, the fitness function evaluates cluster heads and best routes based on constraints.COOT outperforms other Metaheuristics Algorithms like Butterfly Optimization Algorithm, Genetic Algorithm, Tunicate Swarm Gray Wolf Optimization Algorithm, and Bird Swarm Algorithm in simulation with performance measurements and enhancing network functionality and protection.Key methodology points include: • Proposed a multiple constraints clustering and routing technique using COAto solve the most crucial issues that arise in WSNs. • Integrated an advanced fitness function that determines cluster head selection, and the routing path based on residual energy, delay, security, trust, distance, and link quality so that energy load is evenly distributed and credible data flow is maintained across the network and made Innovative and Effective Solution. • Proven Results Demonstrated superior network performance, achieving the lowest delay, highest network lifetime (3571 rounds) and enhanced security (0.8) and trust (0.6) compared to existing algorithms with less energy consumption, making it the most suitable solution for WSN performance improvement.…”
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Fungal chemical warfare: the role of aflatoxin and fumonisin in governing the interaction between the maize pathogens, Aspergillus flavus and Fusarium verticillioides by Timothy R. Satterlee, Jaci A. Hawkins, Trevor R. Mitchell, Qijian Wei, Jessica M. Lohmar, Anthony E. Glenn, Scott E. Gold

“…With these findings, expression of the genetic regulators of secondary metabolism was investigated for both fungi. …”
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A metagenomic catalogue of the ruminant gut archaeome by Jiandui Mi, Xiaoping Jing, Chouxian Ma, Fuyu Shi, Ze Cao, Xin Yang, Yiwen Yang, Apurva Kakade, Weiwei Wang, Ruijun Long

“…We also find that archaea potentially carry antibiotic and metal resistance genes, mobile genetic elements, virulence factors, quorum sensors, and complex archaeal viromes. …”
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Organoid development and applications in gynecological cancers: the new stage of tumor treatment by Yang Li, Meiying Qin, Ning Liu, Chunmei Zhang

“…In contrast to traditional cell lines and patient-derived xenograft (PDX) models, gynecologic cancer organoids accurately mirror the genetic mutations and specific gene expression profiles of primary tumors. …”
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Differential pathological changes in colon microenvironments in acute and chronic mouse models of inflammatory bowel disease by NaYeon Ham, Minji Park, Young-An Bae, Eui-Ju Yeo, YunJae Jung

“…RNA-sequencing revealed genetic changes in acute and chronic colitis, marked by the maintenance of genomic integrity in the acute phase and extracellular matrix dynamics in the chronic phase. …”
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The Effectiveness Of Spiritual Emotional Freedom Technique (SEFT) On The Decrease of Psychological Issues In Cancer Patients: A Systematic Review by Meliawati Putri Salsabila, Enie Novieastari

“…Basically, cancer can occur due to genetic changes (mutations), especially in the gene that regulates growth, namely oncogenes. …”
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Saturated fat in an evolutionary context by Eirik Garnås

“…It is shown that while saturated fatty acids have been consumed by human ancestors across time and space, they do not feature dominantly in the diets of hunter-gatherers or projected nutritional inputs of genetic accommodation. A higher intake of high-fat dairy and meat products produces a divergent fatty acid profile that can increase the risk of cardiovascular and inflammatory disease and decrease the overall satiating-, antioxidant-, and nutrient capacity of the diet. …”
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Unlocking the secrets of the immunopeptidome: MHC molecules, ncRNA peptides, and vesicles in immune response by Arpita Balakrishnan, Arpita Balakrishnan, Gabriela Winiarek, Olga Hołówka, Jakub Godlewski, Agnieszka Bronisz

“…We explore established and emerging insights into MHC molecule interactions with peptides, including the dynamics of peptide loading, transport, and the influence of cellular and genetic variations. The article highlights novel research on non-coding RNA (ncRNA)-derived peptides, which challenge conventional views of antigen processing and presentation and the role of EVs in transporting these peptides, thereby modulating immune responses at remote body sites. …”
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Ship-Borne Phased Array Radar Using GA Based Adaptive α-β-γ Filter for Beamforming Compensation and Air Target Tracking by J. Mar, Chen-Chih Liu, M. B. Basnet

“…In this paper, the adaptive α-β-γ filter is proposed for the ship-borne phased array radar to compensate for the beam pointing error and to track the air target. The genetic algorithm (GA) and the particle swarm optimization (PSO) methods are applied to estimate the gain parameters of adaptive α-β-γ filters, while achieving the optimum objective of minimum root mean square error (RMSE). …”
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Distribution of (1,3)(1,4)-β-D-Glucans in Grains of Polish Oat Cultivars and Lines (Avena sativa L.) – Short Report by Sykut-Domańska Emilia, Rzedzicki Zbigniew, Zarzycki Piotr, Sobota Aldona, Błaszczak Wioletta

“…It was also demonstrated that Dukat cultivar was characterised by an especially valuable triple aleurone layer, which makes this cultivar predestined for further breeding studies as an extremely valuable carrier of genetic information.…”
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The Bipolar Depression Electrical Treatment Trial (BETTER): Design, Rationale, and Objectives of a Randomized, Sham-Controlled Trial and Data from the Pilot Study Phase by Bernardo de Sampaio Pereira Junior, Gabriel Tortella, Beny Lafer, Paula Nunes, Isabela Martins Benseñor, Paulo Andrade Lotufo, Rodrigo Machado-Vieira, André R. Brunoni

“…Biological markers such as blood neurotrophins and interleukins, genetic polymorphisms, heart rate variability, and motor cortical excitability will be assessed. …”
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Structural engineering of stabilized, expanded epitope nanoparticle vaccines for HPV by Michaela Helble, Michaela Helble, Xizhou Zhu, Pratik S. Bhojnagarwala, Kevin Liaw, Yangcheng Gao, Amber Kim, Kelly Bayruns, Madison E. McCanna, Joyce Park, Kylie M. Konrath, Kylie M. Konrath, Sam Garfinkle, Sam Garfinkle, Taylor Brysgel, David B. Weiner, David B. Weiner, Daniel W. Kulp, Daniel W. Kulp

“…We further tested nanoparticles in a genetically diverse, more translationally relevant CD-1 mouse model and demonstrated that both E6 and E7 nanoparticle designs drove a CD8+ biased T-cell response. …”
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THE OPTIMIZATION OF THE PROCESS PARAMETERS IN THE COURSE OF THE ELECTRICAL DISCHARGE MACHINING OF THE MONOCRYSTALLINE SILICON WHICH IS BASED ON THE PARETO FRONTIER by ZHANG LiXin, LI YuXi, SHI WeiChao

“…Aiming at improving the material removal rate and reducing the surface roughness to establish the process parameters optimization model,it designs genetic algorithm for solving optimization problem and get the Pareto optimal solution set. …”
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The Role of the Pathoanatomical Diagnosis «Chronic Gastritis» in the System of Personified Cancer Prevention by A. V. Kononov

“…Biopsy diagnosis of chronic gastritis combined with the evaluation of gene structure (genetic polymorphism) and epigenomic mechanisms (microRNA) allows the risk of gastric cancer to be ranked in a particular patient even with early precancerous changes in the gastric mucosa. …”
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Dysplasia in Inflammatory Bowel Diseases: Definition and Clinical Impact by Karel Geboes, Paul Rutgeerts

“…Additional techniques to search for genetic defects associated with carcinogenesis can help to support the diagnosis. …”
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Segment Any Leaf 3D: A Zero-Shot 3D Leaf Instance Segmentation Method Based on Multi-View Images by Yunlong Wang, Zhiyong Zhang

“…Exploring the relationships between plant phenotypes and genetic information requires advanced phenotypic analysis techniques for precise characterization. …”
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Inference Attacks on Genomic Data Based on Probabilistic Graphical Models by Zaobo He, Junxiu Zhou

“…., leakage unwittingly, or after their releasing intentionally to genetic service platforms), kin-genomic data privacy is threatened. …”
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Standardization of Micropropagation for Four Hybrids of <i>Coffea arabica</i> Through Direct Somatic Embryogenesis by Marileydi Zuta-Puscan, Jegnes Benjamín Meléndez-Mori, Eyner Huaman-Huaman, Yoiner Kalin Lapiz-Culqui, Reyna Stefani Mego-Pérez, Manuel Oliva-Cruz

“…Direct somatic embryogenesis represents a fundamental tool for obtaining genetically homogeneous clones; however, its commercial scaling faces critical challenges at various stages of the process. …”
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Maximizing efficiency and performance of water distribution systems through the implementation of optimization algorithms: A comprehensive analysis of valve and chlorine booster pl... by Mohamadreza Najarzadegan, Mehrtash Eskandaripour

“…By employing advanced optimization algorithms, specifically the Genetic Algorithm (GA) and Slime Mould Algorithm (SMA), the research identifies optimal configurations across two benchmark networks, Jowitt and Xu and GoYang. …”
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