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11641
Bacterial Cellulose: From Biofabrication to Applications in Sustainable Fashion and Vegan Leather
Published 2025-01-01“…Furthermore, recent innovations in synthetic biology and genetic engineering have opened new avenues for improving BC biosynthesis, making it a viable solution for the sustainable fashion industry. …”
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11642
A Unique Source for Innovative Longitudinal Research: The POPLINK Database
Published 2016-03-01“…POPLINK has been built to allow linkage to modern registries, clinical data and medical biobanks, which enables the study of transgenerational effects, heredity and genetic transfers in disease incidence of the population today. …”
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11643
Toward Enhancing the Energy Efficiency and Minimizing the SLA Violations in Cloud Data Centers
Published 2021-01-01“…VMPMOPSO was compared with a simple single-objective algorithm, called First-Fit-Decreasing (FFD), and two multiobjective ant colony and genetic algorithms. Two simulation experiments were conducted to verify the effectiveness and efficiency of the proposed VMPMOPSO. …”
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11644
Metabolomic characterisation of the glioblastoma invasive margin reveals a region-specific signature
Published 2025-01-01“…Isocitrate dehydrogenase wild-type glioblastoma (GBM) is characterised by a heterogeneous genetic landscape resulting from dynamic competition between tumour subclones to survive selective pressures. …”
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11645
Depression and Anxiety Disorders among Patients with Psoriasis: A Hospital-Based Case-Control Study
Published 2012-01-01“…Psoriasis is a common, genetically determined inflammatory and proliferative disease of the skin. …”
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11646
Immunopathogenesis of inflammatory bowel diseases
Published 2013-09-01“…To present analysis of data on immunopathogenesis of inflammatory bowel diseases.Key points. At genetically sensitive animals inflammatory bowel diseases (IBD) develop at various effects on innate and adaptive systems of immune defense (knock-out and transgenic mice), causing changes of expression of significant immunologic factors with distortion of pro- and anti-inflammatory cells and molecules ratio at their contact to microbiota structures. …”
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11647
Tumor-initiating and metastasis-initiating cells of clear-cell renal cell carcinoma
Published 2025-02-01“…MICs result from various genetic changes during subclonal evolution, while TICs reside in the stem of the ccRCC phylogenetic tree of clonal development. …”
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11648
Fuzzy Sliding Mode Control with Moving Sliding Surface of Rotary Inverted Pendulum
Published 2022-09-01“…The boundary values of the membership functions in the fuzzy logic structure have been optimized using genetic algorithm codes in Matlab program. The sum of the squares of the errors is preferred as the objective function. …”
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11649
Cytochrome P450 Metabolism of Betel Quid-Derived Compounds: Implications for the Development of Prevention Strategies for Oral and Pharyngeal Cancers
Published 2013-01-01“…In this review, we summarize the current knowledge base regarding CYP genetic variants and related oral disorders. In clinical applications, we focus on cancers of the oral cavity and pharynx and OPMDs associated with CYP gene polymorphisms, including CYP1A1, CYP2A6, CYP2E1, and CYP26B1. …”
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11650
Formulation and Determination of Tannin and Flavonoid Levels of Anti-Acne Gel Formulation from Red Betel Leaf Extract (Piper crocatum)
Published 2024-04-01“…Acne can be triggered by several factors, genetic, psychological, weather, stress, cosmetics, and bacterial infections. …”
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11651
Active Suspension Based on a Motor-Driving Compacted Double-Gas-Chamber Hydro-Pneumatic Strut
Published 2025-01-01“…The controller is built based on the quarter-car model with the MDHPS model and the optimal values are identified through the Ziegler-Nichols method and Genetic Algorithm (GA). Finally, to investigate the attitude control effect of MDHPS, the full-car model is established based on the co-simulation of Carsim and Matlab/Simulink. …”
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11652
Copy number amplification of FLAD1 promotes the progression of triple-negative breast cancer through lipid metabolism
Published 2025-02-01“…Through an integrated analysis of our TNBC multiomic dataset (n = 465) and subsequent experimental validation, we identify copy number amplification of the metabolic gene flavin-adenine dinucleotide synthetase 1 (FLAD1) as a crucial genetic event that drives TNBC progression. Mechanistically, FLAD1, but not its enzymatically inactive mutant, upregulates the enzymatic activity of FAD-dependent lysine-specific demethylase 1 (LSD1). …”
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11653
Coronary Artery Spasm: New Insights
Published 2020-01-01“…Coronary artery spasm (CAS) defined by a severe reversible diffuse or focal vasoconstriction is the most common diagnosis among INOCA (ischemia with no obstructive coronary artery disease) patients irrespective to racial, genetic, and geographic variations. However, the prevalence of CAS tends to decrease in correlation with the increasing use of medicines such as calcium channel blockers, angiotensin converting enzyme inhibitor, and statins, the controlling management of atherosclerotic risk factors, and the decreased habitude to perform a functional reactivity test in highly active cardiac catheterization centers. …”
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11654
Phylogeny-based comparative analysis of gene expression modulation upon drought stress across three cotton diploids
Published 2025-01-01“…Conclusions This study reveals the diversity of drought response mechanisms among individual cotton species, identifies valuable targets for genetically enhancing drought tolerance, and provides a strategic framework for identifying candidate genes for breeding programs.…”
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11655
Pan-cancer analysis of SOX2: Prognostic implications and potential as a therapeutic target in immune checkpoint modulation
Published 2025-02-01“…This study investigates SOX2 genetic, transcriptomic, and epigenetic alterations across over 30 cancer types. …”
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11656
Asthma in Sickle Cell Disease
Published 2011-01-01“…Hemolysis-driven acute-on-chronic inflammation and dysregulated arginines–nitric oxide metabolism are potential mechanisms by which pulmonary dysfunction could occur in patients with SCD. In patients with a genetic predisposition of atopic asthma, these changes are probably more severe and result in increased susceptibility to sickle cell complications. …”
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11657
The History of a Genuine Fake Philosophical Treatise (Ḥatatā Zar’a Yā‘eqob and Ḥatatā Walda Ḥeywat). Episode 2: The Time of Debunking, The Time in the Wilderness (from 1916 to the...
Published 2021-10-01“…Above all, it provides a new interpretation of the texts based on genetic criticism, and as such, tries to envisage the author, Giusto d’Urbino, at work on the Hatatā Zar’a Yā‘eqob. …”
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11658
Renal affection among type 2 diabetic patients and their families
Published 2023-04-01“…Background and Aim It was believed that both environmental and genetic factors are involved in the pathogenesis of tyrje 2 diabetes mellitus (T2DM). …”
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11659
Low-dose oral minoxidil in a case of short anagen syndrome
Published 2025-12-01“…The findings may also offer insights into the genetic basis of SAS and its overlap with other hair loss conditions, suggesting possible shared therapeutic approaches.…”
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11660
Cellular therapies in rheumatic and musculoskeletal diseases
Published 2025-06-01“…The persistence of these autoreactive B cells within lymphatic organs and inflamed tissues impairs the effectiveness of B-cell-depleting monoclonal antibodies like rituximab.A promising therapeutic approach involves using T cells genetically engineered to express chimeric antigen receptors (CARs) that target specific antigens. …”
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