The PI4K2A gene positively regulates lipid synthesis in bovine mammary epithelial cells and attenuates the inhibitory effect of t10,c12-CLA on lipid synthesis by Tong Mu, Honghong Hu, Xiaofang Feng, Chuanchuan Wang, Juan Zhang, Zhihong Sun, Yaling Gu

“…Our findings have deepened the understanding of the regulatory mechanisms of milk fat synthesis and provide potential genetic targets for the improvement of lactation traits in dairy cows.…”
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Sintesis Dimensi Manipulator Paralel Bidang Dua Derajat Kebebasan Dengan Rantai Kinematik Paralelogram Simetris by Adriyan Adriyan

“…An optimization process using non-sorted dominated genetic algorithm II (NSGA-II) was carried out for maximization of (<em>i</em>) <em>r</em>_MIC (the radius of the maximum inscribed circle) and GCI (global conditioning index), and (ii) <em>r</em>_MIC and GTI (global transmission index). …”
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A novel case of glial transdifferentiation in renal medullary carcinoma brain metastasis by Maria A. Gubbiotti, Ian E. McCutcheon, Priya Rao, Giannicola Genovese, Linghua Wang, Artem Tarasov, Vladislav Putintsev, Amber Berlinski, Danil Stupichev, Kirill Kriukov, Suren Davitavyan, Basim Salem, Alexander Sarachakov, Dmitry Lebedev, Michael Hensley, Alexander Bagaev, Francesca Paradiso, Vladimir Kushnarev, Gleb Khegai, Nizar M. Tannir, Pavlos Msaouel

“…Therefore, given the common genetic signatures in the brain metastasis and the patient’s prior tumor, this case represents a rare event of glial transdifferentiation in a brain metastasis of renal medullary carcinoma following the use of an epigenetic modulator. …”
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Travelogs of Journeys to Lithuania in Early 15th–19th Century: The Problem of Egodocumentality and Typology by Arvydas Pacevičius

“…The attempt at a typology of travel egodocumentation revealed a gap between a genetic taxonomy based on the notion of the personal archive as a treasure trove of memory and a literary classification based on contemporary genres of travel writing. …”
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An Empirical Analysis of the Role of Piano Performance in Alleviating Psychological Trauma in People with Psychological Isolation Disorder by Xia Cao

“…Finally, the support vector machine with optimized parameters of the genetic algorithm was used to classify the positive, neutral, and negative samples with 89.23% accuracy. …”
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Shallow Foundation Settlement Quantification: Application of Hybridized Adaptive Neuro-Fuzzy Inference System Model by Mariamme Mohammed, Ahmad Sharafati, Nadhir Al-Ansari, Zaher Mundher Yaseen

“…This research emphasis on the implementation of newly developed machine learning models called hybridized Adaptive Neuro-Fuzzy Inference System (ANFIS) with Particle Swarm Optimization (PSO) algorithm, Ant Colony optimizer (ACO), Differential Evolution (DE), and Genetic Algorithm (GA) as efficient approaches to predict settlement of shallow foundation over cohesion soil properties. …”
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Neuroinflammation in Autism: Plausible Role of Maternal Inflammation, Dietary Omega 3, and Microbiota by Charlotte Madore, Quentin Leyrolle, Chloé Lacabanne, Anouk Benmamar-Badel, Corinne Joffre, Agnes Nadjar, Sophie Layé

“…Several genetic causes of autism spectrum disorder (ASD) have been identified. …”
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Complete chloroplast genome of Sagina maxima A. Gray (Caryophyllaceae) from Ulleung-do Island, Korea by Asif S. Tamboli, Suhas K. Kadam, Jin-Suk Youn, JiYoung Yang, Young Seok Sim, Jae Hong Pak, Yeon-Sik Choo

“…This study provides the first brief characterization report of the cp. genome from the genus Sagina, which will be useful in future investigations into the genetic resources, species identification, and phylogeny of Sagina.…”
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Molecular Mechanisms of Breast Cancer Drug Resistance and CRISPR/Cas9 Strategies to Overcome by Bashdar Mahmud Hussen, Bnar Saleh Ismael, Saman S. Abdulla, Noor Haval Jamal, Suhad Asad Mustafa, Zana Baqi Najmalddin, Mohammed Fatih Rasul

“…CRISPR/Cas9 gene editing can overcome BC treatment resistance by identifying crucial genetic variables and revealing new therapeutic targets Despite the advantages, there are limitations in the study on CRISPR/Cas9-based gene editing for BC treatment resistance, for example, off-target effects and the improvement of delivery techniques are still major issues. …”
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Individual‐based simulations of genome evolution with ancestry: The GenomeAdmixR R package by Thijs Janzen, Fernando Diaz

“…This and other types of genome admixture have received increasing attention for their implications in speciation, human evolution, Evolve and Resequence (E&R) and genetic mapping. However, a thorough understanding of how local ancestry changes after admixture and how selection affects patterns of local ancestry remains elusive. …”
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Optimal Coordination of TCSC and PSS2B Controllers in Electric Power Systems Using MOPSO Multiobjective Algorithm by Mehrdad Ahmadi Kamarposhti, Hassan Shokouhandeh, Yahya Gholami Omali, Ilhami Colak, Phatiphat Thounthong, William Holderbaum

“…The MOPSO algorithm optimization results are compared with nondominated sorting genetic algorithm (NSGAII) and multiobjective differential evolution (MODE) algorithms. …”
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Finding the Correct Partner: The Meiotic Courtship by Tomás Naranjo

“…In addition, mismatch correction plays a relevant role, especially in polyploids, which evolved genetic systems that suppress pairing between non-homologous related (homoeologus) chromosomes.…”
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Anti-Factor H Antibodies in Egyptian Children with Hemolytic Uremic Syndrome by Shereen Shawky, Hesham Safouh, Mona Gamal, Mohammed M. Abbas, Azza Aboul-Enein, Toshihiro Sawai, Yosra Fahmy, Heba Selim

“…It is primarily caused by dysregulation of the complement alternative pathway due to genetic mutations, mainly in complement factor H genes, or due to anti-factor H autoantibodies (anti-FH), leading to uncontrolled overactivation of the complement system. …”
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Chromosome 15q13.1q13.2 microdeletion in a foetus with severe congenital heart defects: A case report by Thi Ha Vu, Thi Hai Hoang, Thi Sim Nguyen, Khanh Dung Ho, Thi Kim Phuong Doan

“…The use of aCGH in foetuses with abnormal cardiac development diagnosed by routine cardiac colour Doppler ultrasound imaging is recommended for the early detection of congenital genetic abnormalities. This information can provide valuable insight for prenatal diagnostic consultation and decisions regarding pregnancy termination. …”
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Comparative Genomic Analysis of Lactobacillus plantarum: An Overview by Eliane Evanovich, Patricia Jeanne de Souza Mendonça Mattos, João Farias Guerreiro

“…Our results suggest that there is a high rate of transfer of genetic material between the strains. We did not identify any virulence factors and antibiotic resistance genes on the genomes. …”
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Unity of tradition and innovation as a sustainable development factor of digital society by Yu. A. Chernavin

“…The mechanism of unity of tradition and innovation is revealed by relying on the structure of spiritual culture, which has a level character and has behavioral, ideological and genetic formations. The realization of their potential is presented as considering the requirements that have developed over thousands of years, and in the form of meanings and archetypes, often inexplicable, but encouraging certain choices and actions. …”
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CD56-Negative Aggressive NK Cell Leukemia Relapsing as Multiple Cranial Nerve Palsies: Case Report and Literature Review by M. Guerreiro, F. Príncipe, M. J. Teles, S. Fonseca, A. H. Santos, E. Fonseca, P. Gomes, C. Marques, M. Lima

“…The neoplastic natural killer (NK) cells usually harbor the Epstein-Barr virus (EBV) with a latent viral infection pattern type II; they often have a cytoplasmic CD3ε+ and surface CD3−, CD2+, and CD56+ immunophenotype, and they show complex genetic abnormalities affecting multiple tumor suppressor genes and oncogenes. …”
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Design optimization of the podded propulsor considering pod housing drag and propulsion motor performance by Yuhang Zhou, Chengjiang Liu, Yao Yan, Quan Chen, Wenliang Ke

“…Sensitivity analysis revealed that the stator outer diameter and fore taper angle are key factors influencing motor performance and drag, respectively. A genetic algorithm was used to optimize the POD with bi-objective and tri-objective focuses on minimizing drag, maximizing motor efficiency and power density. …”
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East Asian Gene flow bridged by northern coastal populations over past 6000 years by Juncen Liu, Yichen Liu, Yongsheng Zhao, Chao Zhu, Tianyi Wang, Wen Zeng, Bo Sun, Fen Wang, Hui Han, Zhenguang Li, Xiaotian Feng, Peng Cao, Fengshi Luan, Feng Liu, Qingyan Dai, Junfeng Guo, Zimeng Wang, Chengmin Wei, Qiaowei Wei, Ruowei Yang, Weihong Hou, Wanjing Ping, Fan Bai, Bo Miao, Wenjun Wang, Melinda A. Yang, Qiaomei Fu

“…In the ShanDong region, we observed gene flow from populations to the north and south of this region by at least ~7700 BP, and two waves of gene flow associated with the inland Yellow River populations into the ShanDong region during the DaWenKou cultural period (6000-4600 BP) and in the early dynastic period (3500-1500 BP). Reconstructing the genetic history of the Neolithic, Bronze, and Iron Age populations of coastal northern East Asia shows gene flow on both a north-south and an east-west (inland-coastal-island) scale.…”
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Enhancing Akt Imaging through Targeted Reporter Expression by Limin Zhang, Mahaveer S. Bhojani, Brian D. Ross, Alnawaz Rehemtulla

“…The use of molecular imaging technologies has contributed significantly to drug discovery research with an emphasis on drug efficacy, the mechanism of action, and target validation studies. We constructed a genetically engineered hybrid bioluminescent Akt reporter (BAR) molecule that reports on Akt serine/threonine kinase activity. …”
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