A cross-tissue transcriptome-wide association study identified susceptibility genes for age-related macular degeneration by Hongfan Yang, Haofei Huang, Kunlin Pu

“…Abstract Age-related macular degeneration (AMD) is a complex multifactorial disease with a significant genetic component. Despite extensive research efforts, the underlying molecular mechanisms remain elusive, necessitating innovative approaches to identify specific genes involved in the pathogenesis of AMD and to elucidate their functional mechanisms. …”
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Cicer arietinum abscisic acid receptor PYL1 and glycine-rich RNA-binding, abscisic acid-inducible protein-like differential expression under induced draught conditions by Slishchuk Heorhii, Volkova Nataliia, Dilafruz Kholmurodova

“…These results highlight the importance of the abscisic acid receptor PYL1 in adaptation to drought stress and provide insight into the molecular response of chickpea to drought, laying the foundation for further genetic improvement of drought tolerance in this crop.…”
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A Car-Following Model Based on Safety Margin considering ADAS and Driving Experience by Yugang Wang, Nengchao Lyu

“…Other four parameters (SMDL, SMDH, α1, and α2) were calibrated using a classical genetic algorithm, and the effects of ADAS and driving experience in these four parameters were analyzed using T-test. …”
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Human Development X: Explanation of Macroevolution Top-Down Evolution Materializes Consciousness. The Origin of Metamorphosis by Tyge Dahl Hermansen, Søren Ventegodt, Joav Merrick

“…We propose the most important genetic and biochemical process that we think is behind the evolutionary shift as a complicated symbiosis of mechanisms leading to metamorphosis in all biological individuals, from bacteria to humans. …”
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Comparative Analysis of the Full-Length Genome Sequence of a Clinical Isolate of Human Parainfluenza Virus 4B by John A. Lednicky, Thomas B. Waltzek, Micah D. Halpern, Sara B. Hamilton

“…Here, we compare and contrast the genetic features of the three completely sequenced hPIV-4B genomes currently present in GenBank.…”
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Response of Sorghum to Cold Stress at Early Developmental Stage by Amandin Rutayisire, Geoffrey Lubadde, Alice Mukayiranga, Richard Edema

“…Native and adapted to the semiarid tropical regions of Africa, sorghum (Sorghum bicolor) is generally sensitive to cold temperatures, especially during the early developmental stages. However, there is genetic variability within the existing germplasm in terms of tolerance to low temperatures. …”
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Analysis of Fractional Order Mathematical Model of Hematopoietic Stem Cell Gene-Based Therapy by Mohammad Imam Utoyo, Windarto, Aminatus Sa’adah

“…This therapy protects target cells from infections or specifying technic and immune responses to face virus by using genetically modified HSCs. A mathematical model approach could be used to predict the dynamics of HSC gene-based therapy of viral infections. …”
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A Decision-Making Model for Autonomous Vehicles at Urban Intersections Based on Conflict Resolution by Zi-jia Wang, Xue-mei Chen, Pin Wang, Meng-xi Li, Yang-jia-xin Ou, Han Zhang

“…After that, a nondominated sorting genetic algorithm (NSGA-II) and deep deterministic policy gradient (DDPG) are employed to select the optimal motions in comparison with each other. …”
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Occurrence of antibiotics and antibiotic resistance genes at various stages of different aquaculture modes surrounding Tai Lake, China by Congcong Wu, Congcong Wu, Haitao Ye, Mingzhu Xu, Xuan Zhao, Xuejie Zhao, Lina Li, Mingzhi Li, Yanfei Wei, Yuru Li, Baolan Hu, Baolan Hu

“…However, the occurrence of antibiotics and ARGs under different modes and stages of aquaculture has rarely been systematically studied.MethodsThis paper uses qPCR, LC-MS, and High-Throughput sequencing across different culture modes and stages to investigate antibiotics, resistance genes, and microbial communities in the water bodies, and analyze contamination differences between these modes.ResultsThe quinolone and chloramphenicol were the main antibiotics, and the highest absolute abundance genes were quinolone resistance genes (qnrB) and quinolone resistance genes (sul1), with the mobile genetic element (MGE) intI1, both of which exhibited a gradual seasonal increase. …”
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An Estimation Model on Electricity Consumption of New Metro Stations by Zhao Yu, Yun Bai, Qian Fu, Yao Chen, Baohua Mao

“…., passenger volume, air temperature and relative humidity). A genetic algorithm with five-fold cross-validation is used to optimize the hyper-parameters of the SVR model in order to improve its accuracy in estimating the electricity consumption of a metro station (ECMS). …”
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Epidemiology of sickle cell disease in tribal population of Southern Rajasthan, India by Anil Purohit, Ramesh K. Huda, Suman S. Mohanty, Bontha V. Babu

“…Abstract Background & objectives Sickle Cell Disease (SCD), a genetic condition, carries significant public health implications due to its impact on mortality, morbidity and quality of life. …”
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The Borrachudos Granitic Suite: Paleo- to Mesoproterozoic A-type Magmatism in the Southeastern São Francisco Craton (SE Brazil) by IVO ANTONIO DUSSIN, MARIO LUIZ S.C. CHAVES, TANIA MARA DUSSIN, PHILLIPPE ROSSI, JACQUES CHARVET

“…To investigate the nature of this magmatism, mineralogical, geochemical, Nd-Sr isotopic studies in the BGS and genetically related metarhyolites inside the fold belt were carried out. …”
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When to cryopreserve and when to let it go? A systematic review of priorities in wild animal cryobanking by James Edward Brereton, Sarah Louise Spooner, Susan L. Walker, Andrew Mooney, Philippe Wilson, Gabriela F. Mastromonaco, Elena Hunter, Samuel White

“…For wildlife, the most frequently cited priority was to select based on threat level, with convenience sampling and genetic diversity featuring as the second and third most common priorities. …”
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Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice by José Belizário, Luiz Vieira-Cordeiro, Sylvia Enns

“…Here we outline the recent discoveries into how the necrotic cell death execution pathway is engaged in many physiological and pathological outcome based on genetic analysis of knockout mice.…”
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Interaction Effects of Lipoprotein Lipase Polymorphisms with Lifestyle on Lipid Levels in a Korean Population: A Cross-sectional Study by Jung-A Pyun, Sunshin Kim, KyungChae Park, Inkyung Baik, Nam H Cho, InSong Koh, Jong-Young Lee, Yoon Shin Cho, Young Jin Kim, Min Jin Go, Eugene Shim, KyuBum Kwack, Chol Shin

“…Lipoprotein lipase (LPL) plays an essential role in the regulation of high-density lipoprotein cholesterol (HDLC) and triglyceride levels, which have been closely associated with cardiovascular diseases. Genetic studies in European have shown that LPL single-nucleotide polymorphisms (SNPs) are strongly associated with lipid levels. …”
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Research on Equivalent Method of Bench Fatigue Tests for Main Reducers by Zou Xihong, Zhou Qing, Yuan Dongmei, Xiao Yukai, Zhou Yuting, He Ping

“…By collecting the actual driving load spectrum of users and the test site, the road condition and road load spectrum of the test site are reconstructed by using rain-flow counting and elite strategy non-dominated sorting genetic algorithm. In order to verify the effectiveness of the equivalent method, the finite element model of the main reducer is established and the static strength analysis is carried out to verify the mesh independence and model validity. …”
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Subgenome asymmetry of gibberellins-related genes plays important roles in regulating rapid growth of bamboos by Ling Mao, Cen Guo, Liang-Zhong Niu, Yu-Jiao Wang, Guihua Jin, Yi-Zhou Yang, Ke-Cheng Qian, Yang Yang, Xuemei Zhang, Peng-Fei Ma, De-Zhu Li, Zhen-Hua Guo

“…Rapid growth is an innovative trait of woody bamboos that has been widely studied. However, the genetic basis and evolution of this trait are poorly understood. …”
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Replication of the Association of the 6q22.31c Locus near with Pulse Rate in the Korean Population by Nam Hee Kim, Young Jin Kim, Ji Hee Oh, Yoon Shin Cho

“…We have reported two genomewide significant genetic loci responsible for the variation in pulse rate as a part of the Korea Association Resource (KARE) project, the genomewide association study (GWAS) that was conducted with 352,228 single nucleoride polymorphisms typed in 8,842 subjects in the Korean population. …”
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Comparison of ox-LDL Levels in Diabetic Patients with Normo-, Micro-, and Macroalbuminuria with Their First Degree Relatives and the Healthy Control Group by Parisa Behzadi, Firouzeh Torabi, Massoud Amini, Ashraf Aminorroaya

“…In conclusion, the presence and progression of albuminuria in diabetic patients are not related to ox-LDL concentration and genetic predisposition influences the plasma OX-LDL level. …”
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Ten Candidate Genes Were Identified to Be Associated with the Great Growth Differentiation in the Three-Way Cross Hybrid Abalone by Qizhen Xiao, Shihai Gong, Zekun Huang, Wenzhu Peng, Zhaofang Han, Yang Gan, Yawei Shen, Weiwei You, Caihuan Ke, Xuan Luo

“…The three-way cross hybrid abalone ((<i>Haliotis discus hannai</i>♀ × <i>H. fulgens</i>♂)♀ × <i>H. gigantea</i>♂, DF × SS) demonstrated notable diversity in growth traits across the population with genetic differentiation, offering a model for exploring the molecular mechanisms of abalone growth. …”
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