Loss of Lkb1 cooperates with BrafV600E and ultraviolet radiation, increasing melanoma multiplicity and neural‐like dedifferentiation by Kimberley McGrail, Elena González‐Sánchez, Paula Granado‐Martínez, Roberto Orsenigo, Yuxin Ding, Berta Ferrer, Javier Hernández‐Losa, Iván Ortega, Juan Martín‐Caballero, Eva Muñoz‐Couselo, Vicente García‐Patos, Juan A. Recio

“…Histologically, tumors lacking Lkb1 were enriched in neural‐like tumor morphology. Genetic profiling and gene set enrichment analyses of tumor sample mutated genes indicated that loss of Lkb1 promoted the selection of altered genes associated with neural differentiation processes. …”
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Microarray Gene Expression Analysis of Murine Tumor Heterogeneity Defined by Dynamic Contrast-Enhanced MRI by Nick G. Costouros, Dominique Lorang, Yantian Zhang, Marshall S. Miller, Felix E. Diehn, Stephen M. Hewitt, Michael V. Knopp, King C. P. Li, Peter L. Choyke, H. Richard Alexander, Steven K. Libutti

“…Using DCE-MRI in a murine subcutaneous tumor model, we were able to perform pharmacokinetic functional analysis of a tumor, coregistration of MRI images with histological cross-sections, immunohistochemistry, laser capture microdissection, and genetic profiling of tumor heterogeneity based on pharmacokinetic parameters. …”
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Vitamin K and Bone Health: A Review on the Effects of Vitamin K Deficiency and Supplementation and the Effect of Non-Vitamin K Antagonist Oral Anticoagulants on Different Bone Para... by Celia Rodríguez-Olleros Rodríguez, Manuel Díaz Curiel

“…It is an essential vitamin for bone health, taking part in the carboxylation of many bone-related proteins, regulating genetic transcription of osteoblastic markers, and regulating bone reabsorption. …”
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Single-cell transcriptomics of bronchoalveolar lavage during PRRSV infection with different virulence by Byeonghwi Lim, Seung-Chai Kim, Hwan-Ju Kim, Jae-Hwan Kim, Young-Jun Seo, Chiwoong Lim, Yejee Park, Sunirmal Sheet, Dahye Kim, Do-Hwan Lim, Kyeongsoon Park, Kyung-Tai Lee, Won-Il Kim, Jun-Mo Kim

“…Abstract Porcine reproductive and respiratory syndrome virus (PRRSV) causes significant economic losses in the global swine industry due to its high genetic diversity and different virulence levels, which complicate disease management and vaccine development. …”
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Cancer-Associated Immune Resistance and Evasion of Immune Surveillance in Colorectal Cancer by Pietro Parcesepe, Guido Giordano, Carmelo Laudanna, Antonio Febbraro, Massimo Pancione

“…The development of cancer-specific “immune resistance” can be orchestrated either by cooperation with tumor microenvironment or by successive rounds of genetic/epigenetic changes. Recognition of the applicability of this model may provide effective therapeutic avenues for complete elimination of immune-resistant metastatic cells and for enhanced antitumor immunity as part of a combinatorial strategy.…”
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Causal associations between circulating protein ratios and drug resistance in papillary thyroid cancer: a Mendelian randomization study by Jiaqin Deng, Ming Yu, Yihua Gu, Yeqian Lai, Lihong Qiu

“…This study aims to investigate the causal associations between CPLRs and papillary thyroid cancer (PTC), focusing on their potential implications in drug resistance mechanisms. Methods Genetic data for 2821 CPLRs were obtained from the GWAS and FinnGen databases. …”
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Analysis of thermal characteristics of machine tool spindle based on lion swarm optimization algorithm by ZHANG ZhuangZhuang, WANG HongJun, WANG ZengXin

“…Compared with other optimization algorithms such as genetic algorithm, the LSO algorithm has faster convergence speed, higher accuracy, and better global optimal solution. …”
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Diversity and Selection of Cotton Germplasm Based on Morpho-Agronomic Character Performance by Taufiq Hidayat Rahman Side, Mayasari Yamin, Sri Mulyani, Sri Nur Qadri, Luthfi Ayunawati, Agung Pangestu Aji

“…The purpose of this study was to determine the diversity of morpho-agronomic characters and obtain secondary characters and cotton accessions that support the development of a new superior cotton variety. The genetic material used was 266 cotton accessions from the ISFCRI germplasm collection. …”
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Bilateral inverse canine impaction: a case report by Tzu-Yuan Weng, Shiuan-Hui Wang, Chih-Cheng Chen, Lih-Jyh Fuh, Ke-Hung Liu, Jui-Ting Hsu

“…Potential causes of this condition include genetic, systemic, and localized factors. We analyzed this condition in the skeletal remains of a Taiwanese girl aged 11–14 years. …”
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Discovery of a novel Mediterranean Haemaphysalis (Ornithophysalis) doenitzi group tick species infesting Falco eleonorae on Antikythira Island, Greece by Lidia Chitimia-Dobler, Christos Barboutis, Anastasios Bounas, Christina Kassara, Ben J. Mans, Anastasios Saratsis, Ala Tabor

“…Following comprehensive morphological assessment and genetic analysis of the mitochondrial genome by means of next-generation sequencing of both adult and nymphal stages of the ticks, our empirical findings substantiate the delineation of a previously unclassified species. …”
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Mitochondrial Cytochrome c Oxidase Subunit 1 Sequence Variation in Prostate Cancer by Takara A. Scott, Rebecca S. Arnold, John A. Petros

“…Further evaluation of this gene and these mutations may allow for the identification of genetically at-risk populations. The high rate of COI mutations in African-Americans may account for some of the racial disparity observed in prostate cancer.…”
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Blastocystis and Giardia duodenalis infection in a male prison in Spain by Carla Muñoz-Antoli, Jacklyn Comas, María José Irisarri-Gutiérrez, Lucrecia Acosta, José Guillermo Esteban, Rafael Toledo

“…Conclusions: The predominance of ST3 within the prison inmates, together with its low intra-ST genetic variability, reflected inter-human transmission with spatial stability. …”
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In vitro efficacy of plant growth-promoting rhizobacteria isolated from ginger (Zingiber officinale) rhizosphere for biological control of plant pathogens by Ruth Meike Jayanti, Sabrina Ayu Kristianingrum, Andree Wijaya Setiawan

“…Research on the isolation of PGPR from ginger (Zingiber officinale) rhizosphere in Indonesia remains limited, highlighting the need for further exploration to support genetic resource conservation and sustainable agricultural practices. …”
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Evaluation on Filter Performance of Variational Mode Decomposition and Its Application in Separating Closely Spaced Modes by Wenjing Gu, Li Zhou

“…The initial center frequencies could be simply determined by prior estimated modal frequencies of the analyzed signal, while the constraint parameter is optimized utilizing a genetic algorithm (GA). A two-degree-of-freedom parametric system is considered to evaluate the capability of VMD in the separation of closely spaced modes. …”
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Genomic Landscape Reveals Chromosomally-Mediated Antimicrobial Resistome and Virulome of a High-Risk International Clone II Acinetobacter baumannii AB073 from Thailand by Rattiya Cheewapat, Jadsadaporn Redkimned, Sirikran Lekuthai, Thawatchai Kitti, Kannipa Tasanapak, Aunchalee Thanwisai, Sutthirat Sitthisak, Thanet Sornda, Hathaichanok Impheng, Sudarat Onsurathum, Udomluk Leungtongkam, Supaporn Lamlertthon, Siriwat Kucharoenphaibul, Jintana Wongwigkarn, Pantira Singkum, Pattrarat Chanchaithong, Rapee Thummeepak

“…Likewise, mobilome analysis found that AB073 did not carry genetic determinants involving horizontal gene transfer. …”
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Specific features of African swine fever control activities in China by M. D. Lozovoy, S. V. Shcherbinin, A. K. Karaulov

“…The country with the largest swine population in the world achieved rather moderate spread rates if compared to Europe.In addition, the virus strains, which circulated in the Chinese territory, were genetically diverse and different in virulence, leading to a wide range of clinical signs manifested by diseased animals. …”
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Hyperparathyroidism Jaw Tumor Syndrome Presenting as Recurrent Femur Fractures in a Young Woman; a Rare Presentation of a Rare Disease by Piyumi S. A. Wijewickrama, Noel P. Somasundaram

“…Based on the associated clinical manifestations, hyperparathyroidism jaw tumor syndrome was suspected, and genetic studies reported a positive CDC73 mutation with a whole-gene deletion of exon 1–17. …”
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Corneal scarring after epithelium-off collagen cross-linking by Radhika Natarajan, Divya Giridhar

“…Individual patient factors such as variations in healing response and genetic predispositions, associated ocular allergy, and chronic contact lens wear can also impact scar development post-CXL. …”
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Systematic and Cell Type-Specific Telomere Length Changes in Subsets of Lymphocytes by Jue Lin, Joshua Cheon, Rashida Brown, Michael Coccia, Eli Puterman, Kirstin Aschbacher, Elizabeth Sinclair, Elissa Epel, Elizabeth H. Blackburn

“…Leukocyte or peripheral blood mononuclear cell (PBMC) telomere length is a potential biomarker for human aging that integrates genetic, environmental, and lifestyle factors and is associated with mortality and risks for major diseases. …”
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Th1 and Th2 cytokine profile in patients with early onset periodontitis and their healthy siblings by Jiřina Bártová, Zuzana Krátká-Opatrná, Jarmila Procházková, Otakar Krejsa, Jana Dušková, Lubor Mrklas, Helena Tlaskalová, Božena Cukrowská

“…Early onset periodontitis (EOP) is a chronic inflammatory periodontal disease with a strong genetic link affecting individuals aged 17 to 25. …”
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