The emerging roles of aberrant alternative splicing in glioma by Reda Ben Mrid, Sara El Guendouzi, Marco Mineo, Rachid El Fatimy

“…Despite successful advances in understanding glioma, several genetic, epigenetic, and post-transcriptional alterations leave various targeted therapies ineffective, leading to a poor prognosis for high-grade glioma. …”
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Performance analysis of high-rate generalized space code index modulation system by BIAN Lina, ZHANG Qianyu, WU Jiayan

“…The traditional modulation symbols were replaced with the additional phase by the HR-GS-CIM system, and the genetic algorithm (GA) was used to optimize the design of the additional phase, which could acquire high energy efficiency advantage and performance advantage. …”
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Melanoma genomics – will we go beyond BRAF in clinics? by Justyna Mirek, Wiesław Bal, Magdalena Olbryt

“…Abstract In the era of next-generation sequencing, the genetic background of cancer, including melanoma, appears to be thoroughly established. …”
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Faking the News: Intentional Guided Variation Reflects Cognitive Biases in Transmission Chains Without Recall by Stubbersfield Joseph, Tehrani Jamshid, Flynn Emma

“…While copying error is directly analogous to genetic mutation, guided variation is a specifically cultural process that does not have a close parallel in biological evolution. …”
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Synergistic strategies for glioblastoma treatment: CRISPR-based multigene editing combined with immune checkpoint blockade by Xiaolin Liu, Xiao Liu, Xiaonan Luo, Maorong Zhu, Nannan Liu, Juan Li, Qi Zhang, Cheng Zou, Yuxin Wu, Zhengcong Cao, Shuangxin Ma, Weizhong Wang, Guangzhao Yang, Jintao Gu, Wei Liu, Meng Li, Anan Yin, Yalong He, Wei Lin

“…Our approach involved the use of genetic engineering to the long-lasting production of PD-1 and the brain-specific peptide angiopep-2 on the surface of EVs. …”
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Immunosuppressants in modern approaches to treatment of inflammatory bowel diseases by O. B. Schukina, A. G. Kharitonov, A. M. Kharitidis, T. E. Ivashchenko, Yu. A. Nasykhova, T. V. Gabrusskaya, A. Yu. Baranovsky

“…There is no need of study for genetic mutations before prescription of thiopurines, however application of effective methods of evaluation of prognosis of bone marrow toxicity development remains an actual issue. …”
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Genome analysis and prevalence of SARS-CoV-2 Indonesian variants and the correlation with the outbreak timeline by Maria Prevyolita Indra Muliawan, Timotius Christopher Tantokusumo, Amalda Siti Anisa, Kholis Abdurachim Audah

“…Objective: To identify the genetic mutations associated with the transmission and virulence of SARS-CoV-2 variants in Indonesia and to examine their correlation with the outbreak timeline. …”
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The ethics of theft: Reevaluating the impacts of floral larceny on plant reproductive success by Jin-Ru Zhong, Xiao-Fang Jin, Michael C. Orr, Xiao-Qing Li, Yong-Deng He, Sheng-Wei Wang, Qing-Feng Wang, Chun-Feng Yang, Zhong-Ming Ye

“…By altering pollinator behavior, floral larceny may reduce geitonogamy, potentially enhancing genetic diversity. Additionally, factors such as pollinator type, plant mating system, and pollen limitation were identified as key moderators of these effects. …”
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Challenges in Diagnosing Intrahepatic Cholangiolithiasis in a 39-Year-Old Patient by A. K. Guseva, O. N. Sergeyeva, T. P. Nekrasova, O. T. Imaraliev, A. V. Okhlobystin, Y. N. Shirokova, A. S. Ostrovskaya, M. S. Zharkova, A. S. Cherenda, V. T. Ivashkin

“…Cholangiolithiasis occurs in more than half of cases of primary sclerosing cholangitis and can be both a complication and a cause of secondary sclerosing cholangitis, maintaining inflammation in the ducts and facilitating stone formation. Genetic mutations are known to contribute to the development of gallstones in young patients, including low phospholipid-associated cholelithiasis. …”
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Vitamin D and Selenium: Review of Clinical Trials of Synergistic Effects on Thyroid Antibody Levels and Disease Progression in Hashimoto’s Thyroiditis by Agnieszka Starzyk, Piotr Charzewski

“… Introduction: Hashimoto's Thyroiditis (HT) is a common autoimmune thyroid disorder caused by genetic predispositions and environmental factors, such as iodine imbalance, selenium deficiency, and stress. …”
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Parathyroid carcinoma and pheochromocytoma in a patient with neurofibromatosis type 1: a rare association by Jardelina Brena Rocha Leite, Nicole Ramalho De Freitas, Rafaella Nelice de Holanda Cardoso, Erik Trovão Diniz, Gabriel Rodrigues de Assis Ferreira, Fernão Henrique Costa e Alvim, Camila Ribeiro Coutinho Madruga, Ana Carolina Thé Garrido, Luciano Albuquerque, Patricia Sampaio Gadelha, Ruy Lyra, Lucio Vilar

“…Surgical intervention confirmed the presence of pheochromocytoma and parathyroid carcinoma. Genetic analysis corroborated NF1 with a pathogenic variant in the NF1 gene. …”
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Optimal compensation method for centrifugal impeller considering aerodynamic performance and dimensional accuracy by Tao Zhou, Sitong Xiang, Hainan Zhang, Jianguo Yang

“…Finally, based on the mapping model, the second-generation non-dominated sorting genetic algorithm was used to optimize the control points of the mirror compensation surface, and thereby obtain the optimal compensation surface. …”
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Facultative parthenogenesis: a transient state in transitions between sex and obligate asexuality in stick insects? by Larose, Chloé, Lavanchy, Guillaume, Freitas, Susana, Parker, Darren J., Schwander, Tanja

“…These populations comprised three genetic lineages. Females from all lineages were capable of parthenogenesis (with variable efficiency) but their propensity to reproduce sexually after mating varied extensively. …”
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Characterization and phylogenetic analysis of the chloroplast genome of endangered Impatiens chishuiensis by LAN Wenxiang, MO Qing, HUANG Haiquan, HUANG Meijuan

“…[Objective] The chloroplast genome structure and phylogenetic location of Impatiens chishuiensis were studied in order to provide scientific basis for the conservation of plant germplasm resources, genetic diversity, and phylogeny of I. chishuiensis. …”
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The intestinal microbiome as a separate organ by Yu. O. Shulpekova

“…Intestinal microbiome encompasses about 1014 microorganisms, over 99% of microbiome genetic material belong to bacteria. In healthy people three basic enterotypes (according to the type of dominating species) are defined. …”
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A human pathogenic hantavirus circulates and is shed in taxonomically diverse rodent reservoirs. by Samuel M Goodfellow, Robert A Nofchissey, Chunyan Ye, Jaecy K Banther-McConnell, Thanchira Suriyamongkol, Joseph A Cook, Jonathan L Dunnum, Ivana Mali, Steven B Bradfute

“…<h4>Results</h4>We conducted an extensive survey of SNV genetic prevalence in wild-caught small mammal communities throughout New Mexico and observed that 27% of all animals were positive for SNV. …”
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Case report of familial hypercholesterolemia with internal carotid neck swelling by Sudesh Kumar, Prajna Ray, Ranita Sahana

“…This case highlights the significance of conscious and proactive genetic screening for familial hypercholesterolemia especially in consanguineous marriage, to diagnose, treat and prevent mortality with premature coronary artery disease.…”
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In-service teachers' self-efficacy to practice inclusive education at public primary schools in the Amhara region: Implications for teacher education by Tsegie Genet Zegeye, Solomon Kassie Alem, Ayetenew Abie

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Psoriasis: Unraveling Disease Mechanisms and Advancing Pharmacological and Nanotechnological Treatments by Miao M, Yan J, Sun Y, Liu J, Guo S

“…The identification of age, gender, and genetic factors contributing to these complex conditions has been pivotal in developing novel pharmacological and technological treatments. …”
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Impacts of Climate Change on the Plant Water Interactions by Turyasingura, Benson, Ayiga, Natal

“…It was also found that drought was one of the most significant biotic challenges faced by plants, with considerable genetic variation in water deficit responses. There is a need for research on climate change to ease biodiversity conservation.…”
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