Investigating the correlation of hip circumference to cardiovascular disease and type‐2 diabetes using Mendelian randomization by Hongtao Liu, Zhaoyu Li, Su Yan, Shaopeng Ming

“…Design MR analysis utilized genetic variation from the MR Base in a two‐sample analysis. …”
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Influence of Endogenous Cardiac Glycosides, Digoxin, and Marinobufagenin in the Physiology of Epithelial Cells by Alejandro Ogazon del Toro, Lidia Jimenez, Lorena Hinojosa, Jacqueline Martínez-Rendón, Aida Castillo, Marcelino Cereijido, Arturo Ponce

“…These changes, induced by digoxin and marinobufagenin on GJIC and TER, were not observed on MDCK-R, a modified MDCK cell line that has a genetically induced insensitive α1 subunit, indicating that Na-K-ATPase acts as a receptor mediating the actions of both ECG. …”
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Diagnostics and treatment of cardiac achalasia and cardiospasm: guidelines of the Russian gastroenterological association by V. T. Ivashkin, A. S. Trukhmanov, E. A. Godzhello, I. V. Mayev, Yu. V. Evsyutina, T. L. Lapina, O. A. Storonova

“…Three main hypotheses of disease etiology are discussed: genetic, contagious and autoimmune. Clinical symptoms of disease: difficulty of passage of solid and liquid food through the esophagus, vomiting, in certain cases - chest pain; severe disease is accompanied by cough and weight loss. …”
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Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study by Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Cristian Papara, Katja Bieber, David A. De Luca, Jan Philipp Klein, Marlene A. Ludwig, Philip Curman, Philip Curman, Philip Curman, Philip Curman, Artem Vorobyev, Astrid Dempfle, Ralf J. Ludwig

“…CIDs develop over the span of several years, and the risk of developing CIDs has been linked to genetic and environmental factors. Thus, modification of environmental factors is a promising approach for the prevention of CIDs. …”
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Colonic Mucosal Microbiota in Colorectal Cancer: A Single-Center Metagenomic Study in Saudi Arabia by Ahmed O. Alomair, Ibrahim Masoodi, Essam J. Alyamani, Abed A. Allehibi, Adel N. Qutub, Khalid N. Alsayari, Musaad A. Altammami, Ali S. Alshanqeeti

“…Background and Aim. Because genetic and geographic variations in intestinal microbiota are known to exist, the focus of this study was to establish an estimation of microbiota in colorectal cancer (CRC) patients in Saudi Arabia by means of metagenomic studies. …”
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Understanding the educational inequalities in suicide attempts and their mediators: a Mendelian randomisation study by Jing Wang, Ye Yang, Rui Gao, Lilu Ding, Jiahao Zhu, Dan Zhou, Yingjun Li, Houpu Liu

“…We systematically evaluated 42 putative mediators within the causal pathway connecting reduced educational attainment to suicide attempts and employed two-step and multivariable MR to quantify the proportion of the mediated effect.Results In the combined analysis of iPSYCH and FinnGen, each standard deviation (SD) decrease in genetically predicted educational attainment (equating to 3.4 years of education) was associated with a 105% higher risk of suicide attempts (odds ratio (OR): 2.05; 95% confidence interval (CI): 1.81 to 2.31). …”
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Mapping C. difficile TcdB interactions with host cell-surface and intracellular factors using proximity-dependent biotinylation labeling by Jennifer S. Ward, Karl J. Schreiber, John Tam, Ji-Young Youn, Roman A. Melnyk

“…Proximity-dependent biotinylation approaches offer an orthogonal approach to complement genetic screens. Here, we evaluate the potential of this method to identify host-toxin interactions on the cell surface and in the cytosol, where the toxin modifies essential host targets. …”
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Multivariate Analysis of Phenotypic Diversity of Rice (Oryza sativa L.) Landraces from Lamjung and Tanahun Districts, Nepal by Anup Dhakal, Amrit Pokhrel, Shishir Sharma, Ankur Poudel

“…The magnitude and nature of genetic divergence play a vital role in the selection of the desirable landraces for its utilization in the breeding program. …”
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Pheochromocytoma in Congenital Cyanotic Heart Disease by Carmen Aresta, Gianfranco Butera, Antonietta Tufano, Giorgia Grassi, Livio Luzi, Stefano Benedini

“…Studies on genome-wide transcription patterns have shown that many genetic alterations implicated in pheochromocytoma-paraganglioma (P-PGL) syndromes cluster in a common cellular pathway leading to aberrant activation of molecular response to hypoxia in normoxic conditions (the pseudohypoxia hypothesis). …”
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Ultrasonic and Microwave-assisted Solid-Liquid Extraction of Ginkgo biloba Phenolics: Study about Mass Transfer and PID Control by Chi XU, Hebin XU, Rui ZHU, Jing LI, Dandan LI, Yongbin HAN, Yi ZHENG, Yang TAO

“…Furthermore, fuzzy-PID controllers optimized by genetic algorithms or particle swarm optimization (PSO) algorithms outperformed traditional PID controller and individual fuzzy-PID controller to control the extraction process, achieving faster convergence with minimal overshoot. …”
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Study of possible intrauterine infection of goat fetus with caprine arthritis-encephalitis virus by V. Yu. Koptev, N. A. Shkil, N. Yu. Balybina, T. N. Belenkova

“…The etiologic agent of caprine arthritis-encephalitis (CAE) is a virus of the Retroviridae family, which is part of the group of small ruminant lentiviruses subdivided into five genetic groups. A number of reasons prevent timely disease diagnosis, for example, lack of a legal framework regulating preventive measures, prolonged asymptomatic virus-carrier state, and absence of pathognomonic symptoms. …”
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Unlocking the Healing Potential: A Comprehensive Review of Ecology and Biology of Medical‐Grade Honey in Wound Management and Tissue Regeneration by Parmis Barazesh, Helia Hajihassani, Fatemeh Motalebi, Seyedeh Mobina Hosseini Neiresi, Romina Hajihassani, Ahmad Reza Mehrabian

“…The effectiveness of MGH in wound healing remains debated, with mixed results from trials. Genetic modification of bees to enhance MGH's properties could make it more competitive against conventional treatments. …”
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Quality of life disparities among Mexican people with systemic lupus erythematosus. by Ana Laura Hernández-Ledesma, Domingo Martínez, Elizabeth Fajardo-Brigido, Talía V Román-López, Karen J Nuñez-Reza, Andrea Y Tapia-Atilano, Sandra V Vera Del Valle, Donají Domínguez-Zúñiga, Lizbet Tinajero-Nieto, Angélica Peña-Ayala, Estefania Torres-Valdez, Gabriel Frontana-Vázquez, María Gutiérrez-Arcelus, Florencia Rosetti, Sarael Alcauter, Miguel E Rentería, Alejandra E Ruiz-Contreras, Deshiré Alpízar-Rodríguez, Alejandra Medina-Rivera

“…Higher prevalence and worst outcome have been reported among people with systemic lupus erythematosus with non-European ancestries, with both genetic and socioeconomic variables as contributing factors. …”
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Perforin-2 is dispensable for host defense against Aspergillus fumigatus and Candida albicans by Mariano A. Aufiero, Li-Yin Hung, De'Broski R. Herbert, Tobias M. Hohl

“…However, when we compared Mpeg1−/− mice with co-housed Mpeg+/+ littermate controls, these differences were no longer observed, indicating that initial findings were likely influenced by differences in the murine genetic background or the microbiota composition. …”
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Infective agents and polymyalgia rheumatica: key discussion points emerging from a narrative review of published literature by Ciro Manzo, Marco Isetta, Alberto Castagna

“…According to our review, the search for a specific infectious agent, however intriguing, appears to be stagnating. Genetic background and epigenetic regulation probably play a key role. …”
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Effects of Production System With or Without Growth-Promoting Technologies on Growth and Blood Expression of (Cyto)Chemokines and Heat Shock and Tight Junction Proteins in <i>Bos t... by Mark Branine, Ashley K. Schilling-Hazlett, Pedro H. V. Carvalho, Kim R. Stackhouse-Lawson, Edilane C. Martins, Julia T. da Silva, Laura Amundson, Chris Ashworth, Mike Socha, Sami Dridi

“…This could open new vistas for future research to identify molecular signatures for non-invasive stress monitoring and/or marker-assisted genetic selection for robustness and resilience to HS.…”
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High Serum Level of IL-17 in Patients with Chronic Obstructive Pulmonary Disease and the Alpha-1 Antitrypsin PiZ Allele by Margarita Y. Pervakova, Alexandra V. Mazing, Sergey V. Lapin, Olga Y. Tkachenko, Anna I. Budkova, Elena A. Surkova, Vladimir L. Emanuel, Olga N. Titova

“…Chronic obstructive pulmonary disease (COPD) is multifactorial disease, which is characterized by airflow limitation and can be provoked by genetic factors, including carriage of the PiZ allele of the protease inhibitor (Pi) gene, encoding alpha-1 antitrypsin (A1AT). …”
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Exploring ketogenic diet resistance in glucose transporter type 1 deficiency syndrome: A comprehensive review and critical appraisal by Raffaele Falsaperla, Vincenzo Sortino, Gerhard Josef Kluger, Thomas Herberhold, Andrea Rüegger, Pasquale Striano, Martino Ruggieri, Joerg Klepper, Georgia Ramantani

“…EEG consistently revealed 2–3.5 Hz generalized spike‐and‐wave discharges. Genetic investigations revealed point mutations and deletions in two cases each. …”
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Resolution of unilateral sensorineural hearing loss in a pediatric patient with a severe phenotype of Muckle-Wells syndrome treated with Anakinra: a case report and review of the l... by Cinzia Marchica, Faisal Zawawi, Dania Basodan, Rosie Scuccimarri, Sam J. Daniel

“…Of note, the patient’s history was significant for conductive hearing loss, speech delay, as well as recurrent acute otitis media episodes. Genetic analysis was performed and diagnosis of MWS was confirmed due to the presence of a NLRP3 gene mutation. …”
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Effect of Bovine Serum Albumin (BSA) Concentration on Cryopreservation of Booroolong Frog Sperm with Evaluation of Post-Thaw Motility in Caffeine by Zara M. Anastas, Aimee J. Silla, Phillip G. Byrne, Rebecca J. Hobbs, Michael S. McFadden, Jonathan Daly, Justine K. O’Brien

“…Reproductive technologies, including sperm cryopreservation, offer conservationists enhanced capacity to genetically manage populations and improve the outcomes of conservation breeding programs (CBPs). …”
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