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10201
The Role of the Enterohepatic Circulation of Bile Salts and Nuclear Hormone Receptors in the Regulation of Cholesterol Homeostasis: Bile Salts as Ligands for Nuclear Hormone Recept...
Published 2003-01-01“…The coordinated effect of lipid activated nuclear hormone receptors; liver X receptor (LXR), bound by oxysterol ligands and farnesoid X receptor (FXR), bound by bile acid ligands, act as genetic transcription factors to cause feed-forward cholesterol catabolism to bile acids and feedback repression of bile acid synthesis, respectively. …”
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10202
Two decades of occurrence of non-pathogenic rabbit lagoviruses in Italy and their genomic characterization
Published 2024-11-01“…This study aimed firstly to indirectly show through a seroepidemiological survey from 1998 to 2008 the circulation of RCVs strains in rabbit farms and then to genetically characterise RCV strains diagnosed in Italy in faecal and intestinal samples of wild and farmed rabbits collected in various regions in the following years (2000–2022). …”
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10203
Enhancing Campus Mobility: Simulated Multi-Objective Optimization of Electric Vehicle Sharing Systems Within an Intelligent Transportation System Frameworks
Published 2025-01-01“…A simulation model was developed in MATLAB, utilizing the Non-dominated Sorting Genetic Algorithm (NSGA-II), a powerful multi-objective optimization technique that balances conflicting objectives to achieve the best trade-offs for operational efficiency. …”
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10204
Arbuscular Mycorrhizal Fungi Associated with Myrciaria dubia in the Amazonia Region, Peru
Published 2024-01-01“…Likewise, the molecular analysis detected the presence of genetic material (rDNA) corresponding to AMF in the roots of both accessions. …”
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10205
Studies on the Association of GCK and GCKR Polymorphisms with Susceptibility to Gestational Diabetes Mellitus: A Meta-Analysis
Published 2025-01-01“…Results: We included 20 studies, comprising 9745 GDM women and 15,830 controls. All genetic models showed a strong correlation between the GCK rs1799884 polymorphism and GDM, with carriers of the A allele exhibiting an increased risk. …”
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10206
Occurrence and Multi-Locus Genotyping of <i>Giardia duodenalis</i> in Black Goats from Fujian Province, China
Published 2025-01-01“…To evaluate the prevalence and genetic diversity of <i>G. duodenalis</i> in black goats, we collected 539 fecal samples from nine districts in Fujian Province, China. …”
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10207
Muscle parameters in men and oxidative stress markers
Published 2025-01-01“…Factors like lifestyle, diet, and genetic predisposition, which were not controlled in this study, could also influence the observed outcomes and should be included in future research.…”
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10208
A Case-Control Association Study of RANTES (-28C>G) Polymorphism as a Risk Factor for Parkinson’s Disease in Isparta, Turkey
Published 2016-01-01“…We have examined whether genetic polymorphisms at the genes encoding chemokines IL-8 (-251A>T), MCP-1 (-2518A/G), and RANTES (-28C>G) and chemokine receptors CCR2 (V64I) and CCR5 (-Δ32) were associated with sporadic PD risk in Isparta, Turkey. …”
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10209
Challenges Faced by Nurses in Transitioning Pediatric Sickle Cell Disease Patients to Adult Care
Published 2025-02-01“…Background Sickle-cell disease is a common genetic red blood cell disorder with global concern. …”
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10210
Identification of Candidate Genes Associated with Meat Production of Aberdeen Angus Cattle
Published 2025-01-01“…Blood samples from Aberdeen Angus bulls (n = 260) were used as material for SNP genotyping. Genetic architecture for the kill yield trait showed the presence of 31 SNPs. …”
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10211
Sprawność fizyczna dzieci wiejskich i miejskich z niskiej grupy społeczno-ekonomicznej na Jukatanie (Meksyk)
Published 2003-12-01“…However, differences in stature are observed between ethnic as well as between rural and urban groups. This may have the genetic origin (Creoles and Mayas), and in the case of different localities, it may also be caused by more various nutrition in towns than in villages.…”
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10212
Biomarker discovery and phytochemical interventions in Alzheimer's disease: A path to therapeutic advances
Published 2025-02-01“…There is an urgent need to identify novel molecular markers for the diagnosis and treatment of AD. Genetic biomarkers hold promising potential in this regard. …”
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10213
Food hardness preference reveals multisensory contributions of fly larval gustatory organs in behaviour and physiology.
Published 2025-01-01“…Here, we identified that larvae ingest and navigate towards specific food substrate hardnesses and probed the role of gustatory organs in this behaviour. By developing a genetic tool targeting specifically gustatory organs, we show that these organs are major contributors for evaluation of food hardness and ingestion decision-making. …”
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10214
Utility of Integrated Analysis of Pharmacogenomics and Pharmacometabolomics in Early Phase Clinical Trial: A Case Study of a New Molecular Entity
Published 2018-09-01“…The pharmacogenomics screening was performed from whole blood samples using the Affymetrix DMET (Drug-Metabolizing Enzymes and Transporters) Plus microarray, and confirmation of genetic variants was performed using real-time polymerase chain reaction. …”
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10215
A comprehensive analysis of the epidemiological and genomic characteristics of global Serratia Marcescens
Published 2025-01-01“…Phylogenetic analysis highlighted significant genetic diversity and distinct evolutionary lineages. …”
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10216
Melanin-like nanoparticles slow cyst growth in ADPKD by dual inhibition of oxidative stress and CREB
Published 2024-11-01“…Autosomal dominant polycystic kidney disease (ADPKD) is a chronic genetic disorder closely associated with increased oxidative stress and featured by the progressive enlargement of cysts originating from various segments of the renal tubules. …”
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10217
Tracking the correlation of mineral intakes among family pairs over nine years: a longitudinal study
Published 2025-01-01“…Methods FCOR command of the Statistical Analysis for Genetic Epidemiology software was used to determine the correlation coefficients of minerals in relative pairs. …”
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10218
Waterlogging Effect on Growth, Yield and Physiological Responses of Blackgram (Vigna Mungo L.) Genotypes
Published 2025-02-01“…In the future, waterlogging stress tolerant varieties with more suitable genetic base of blackgram plants needed to identify and utilize the novel traits of donors are now required in breeding programs.…”
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10219
GNA15 predicts poor outcomes as a novel biomarker related to M2 macrophage infiltration in ovarian cancer
Published 2025-02-01“…BackgroundThe exploration of genetic signatures within the ovarian cancer (OC) tumor microenvironment (TME) remains limited. …”
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10220
Betula pendula Roth. survival and growth in treeline is affected by genotype and environment
Published 2025-01-01“…These results demonstrate that the acclimation capacity of B. pendula allows its distribution to expand north from the present range; however, local abiotic environmental conditions (soil fertility and winter temperatures) and other selection pressures (herbivory) are likely to affect the genetic structure and growth of B. pendula populations.…”
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