HIF-1α Is Associated with Resistance to Hypoxia-Induced Apoptosis in Ameloblastoma by Katherine Julissa Palma Valladares, Karolyny Martins Balbinot, Antonia Taiane Lopes de Moraes, Maria Sueli da Silva Kataoka, Aline Maria Pereira Cruz Ramos, Rommel Thiago Jucá Ramos, Artur Luiz da Costa da Silva, Ricardo Alves Mesquita, David Normando, Sérgio de Melo Alves Júnior, João de Jesus Viana Pinheiro

“…To contribute to the study, an analysis of expression and genetic interaction was performed using the cell line AME-1. …”
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Optimal Sizing of a Hybrid Renewable Photovoltaic-Wind System-Based Microgrid Using Harris Hawk Optimizer by Abdullrahman A. Al-Shamma’a, Hassan M. Hussein Farh, Abdullah M. Noman, Abdullah M. Al-Shaalan, Abdulaziz Alkuhayli

“…The efficacy of HHO is investigated, and its performance was compared with seven metaheuristic techniques, grasshopper optimization algorithm (GOA), cuckoo search optimizer (CSO), genetic algorithm (GA), Big Bang–Big Crunch (BBBC), coyote optimizer, crow search, and butterfly optimization algorithm (BOA), to attain the HRE microgrid optimal sizing based on annualized system cost (ASC) reduction. …”
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The Potential Applications of Stem Cell Conditioned Medium Secretome in Knee Cartilage Regeneration: A Systematic Review by I Gusti Ngurah Wien Aryana, Febyan Febyan, Nyoman Gede Grenata Nanda Ustriyana

“…Background: Articular cartilage injuries often result from trauma, genetic predisposition, and degeneration. These injuries lack inherent regeneration mechanisms due to the absence of blood vessels and limited progenitor cell entry. …”
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Genomic epidemiology and antimicrobial resistance of Morganella clinical isolates between 2016 and 2023 by Wentao Zhu, Qian Liu, Jinlv Liu, Jinlv Liu, Yaqi Wang, Yaqi Wang, Hong Shen, Ming Wei, Ji Pu, Li Gu, Jing Yang, Jing Yang, Jing Yang

“…Together with epidemiological data, isolates of four genetic clusters could be possible nosocomial transmissions. …”
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Reduced Representation and Whole‐Genome Sequencing Approaches Highlight Beluga Whale Populations Associated to Eastern Canada Summer Aggregations by Luca Montana, Trevor T. Bringloe, Audrey Bourret, Caroline Sauvé, Arnaud Mosnier, Steven H. Ferguson, Lianne Postma, Véronique Lesage, Cortney A. Watt, Mike O. Hammill, Geneviève J. Parent

“…Beluga whales (Delphinapterus leucas) inhabit the circumpolar Arctic and form discrete summer aggregations. Previous genetic studies using mitochondrial and microsatellite loci have delineated distinct populations associated to summer aggregations but the extent of dispersal and interbreeding among these populations remains largely unknown. …”
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The correlation between the expression of androgen receptor splice variant-7 (AR-V7) protein with the time of occurrence of castration-resistant prostate cancer and overall surviva... by Indrawarman Soerohardjo, Narpati Wesa Pikatan, Andy Zulfiqqar, Irianiwati Widodo, Didik Setyo Heriyanto

“…Abstract Introduction Prostate cancer follows a natural trajectory characterized by genetic alterations that transform initially hormone-sensitive cancer cells into castration-resistant prostate cancer (CRPC), which is associated with high mortality. …”
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Promoter Methylation Precedes Chromosomal Alterations in Colorectal Cancer Development by Sarah Derks, Cindy Postma, Peter T. M. Moerkerk, Sandra M. van den Bosch, Beatriz Carvalho, Mario A. J. A. Hermsen, Walter Giaretti, James G. Herman, Matty P. Weijenberg, Adriaan P. de Bruïne, Gerrit A. Meijer, Manon van Engeland

“…Background: Colorectal cancers are characterized by genetic and epigenetic alterations. This study aimed to explore the timing of promoter methylation and relationship with mutations and chromosomal alterations in colorectal carcinogenesis. …”
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Phylogenetic Analysis and Extracellular Enzyme Profiles of Yeast Strains Isolated from Raspberry Fruits by Melih Günay, Tulay Turgut Genc

“…Yeast strains were isolated and then identified by using the analysis of ITS1-5.8S-ITS2 rDNA gene sequences. The phylo-genetic analysis of all yeast strains was carried out by using the MEGA–X phylogenetic analysis tool. …”
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Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis by Shumin Zhao, Shumin Zhao, Ranran Chen, Ranran Chen, Yi An, Yali Zhang, Yali Zhang, Cheng Ma, Ying Gao, Ying Gao, Yanchao Lu, Yanchao Lu, Fei Yang, Fei Yang, Xue Bai, Xue Bai, Jingjing Zhang, Jingjing Zhang, Jingjing Zhang

“…IntroductionAmyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the loss of motor neurons (MNs). Genetic mutations in Optineurin (OPTN) and Superoxide Dismutase 1 (SOD1) have been identified as causal factors for ALS. …”
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Sulfatase modifying factor 2 as a predictive biomarker for urothelial carcinoma by Wei-Ting Kuo, Yi-Chen Lee, Jia-Bin Liao, Ching-Jiunn Tseng, Yi-Fang Yang

“…In this study, we used an online database and immunohistochemistry to assess genetic changes and the mRNA and protein expression of SUMFs and related candidate targets in UC. …”
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Therapeutic role of isoflavones from traditional medicine in the management of polycystic ovary syndrome by Ashwini Armarkar, Prafulla Sabale, Satyendra Prasad, Vidya Sabale, Lata Potey, Dipti Masram

“…The etiology of PCOS involves a complex interplay of factors, including genetic predisposition, neuroendocrine dysregulation, contemporary lifestyle practices, and obesity. …”
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Molecular identification and phylogenetic analysis of Cysticercus tenuicollis isolated from sheep in Mosul city, Iraq by Omer K. Alhankawe, Nadia S. Alhayali, Donea A. Abdullah

“…GenBank accession numbers were registered. Genetic relatedness revealed that the local C. tenuicollis isolates were more closely related to isolates from Sulaymaniyah and Iran. …”
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XRCC5 VNTR, XRCC6 -61C>G, and XRCC7 6721G>T Gene Polymorphisms Associated with Male Infertility Risk: Evidences from Case-Control and In Silico Studies by Danial Jahantigh, Abasalt Hosseinzadeh Colagar

“…We evaluate the association between genetic polymorphisms of XRCC5 VNTR, XRCC6 -61C>G, and XRCC7 6721G>T with male infertility susceptibility. …”
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Research on Simulation and Performance Optimization of Mach 4 Civil Aircraft Propulsion Concept by Min Chen, Zihao Jia, Hailong Tang, Yi Xiao, Yonghang Yang, Feijia Yin

“…Finally, a multiobjective optimization tool made up of a response surface method and a genetic algorithm was developed to optimize the design parameters and the control law of the TBCC engine, in order to make the Mach 4 supersonic civil aircraft engine with better performance, lower noise, and lower emissions. …”
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Comparison of Blood and Tissue Eosinophil Count and Blood IgE in Patients with Chronic Sinusitis and Nasal Polyps by Masoud Asghari, Shadi Izadpanahi, Mina Heidari Esfahani

“…Chronic sinusitis is a multifactorial disease and the range of causes varies from environmental factors to genetic factors. The purpose of this study was to compare blood and tissue eosinophils and serum IgE levels in patients with chronic sinusitis with nasal polyp in Vali-e-Asr hospital in 1397. …”
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Equine Trypanosomiasis: Molecular Detection, Hematological, and Oxidative Stress Profiling by Mostafa Shoraba, Salma A. Shoulah, Faysal Arnaout, Abdelfattah Selim

“…However, there are no available data about the genetic characterization of this parasite in horses in Egypt. …”
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Crashworthiness Design and Multiobjective Optimization for Hexagon Honeycomb Structure with Functionally Graded Thickness by Ruixian Qin, Junxian Zhou, Bingzhi Chen

“…In addition, three surrogate models, including radial basis function (RBF), response surface method (RSM), and kriging (KRG), are compared in the accuracy of predicting SEA and PCF and capacity for optimization design of FGT honeycomb structure; the Nondominated Sorting Genetic Algorithm (NSGA-II) is applied to obtain the Pareto optimal solutions for the maximum thickness, minimum thickness, and thickness variation gradient exponent of a honeycomb wall. …”
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Melatonin influence on miRNA expression in sperm, hypothalamus, pre-frontal cortex and cerebellum of Wistar rats. by Mísia Helena da Silva Ferro, Ingrid Morante, Fernanda Akane Nishino, Camila Estevam, Fernanda Gaspar do Amaral, José Cipolla-Neto, Taiza Stumpp

“…Its action on sperm is of particular interest, since they transfer genetic and epigenetic information to the offspring, including microRNAs, configuring a mechanism of paternal epigenetic inheritance. …”
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Association between normal saline infusion volume in the emergency department and acute kidney injury in heat stroke patients: a multicenter retrospective study by Lan Chen, Junlu Zhao, Liyun Lu, Zhumei Gong, Shuying Xu, Xiaoling Yang, Yuping Zhang, Xiuqin Feng

“…Multivariate regression models, random forest imputation, and genetic and propensity score matching were used to explore the relationship between NS infusion and outcomes.Results The mean volume of NS infusion in the emergency department (ED) was 3.02 ± 1.45 L. …”
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Parameter Acquisition Study of Mining-Induced Surface Subsidence Probability Integral Method Based on RF-AGA-ENN Model by Jinman Zhang, Liangji Xu, Jiewei Li, Yueguan Yan, Ruirui Xu

“…To obtain more accurate PIM parameters in the absence of observational data, we propose a combined machine learning model (RF-AGA-ENN)—random forest (RF) extracts the best combination of features as the input layer of Elman neural network (ENN); ant colony algorithm (ACO) and genetic algorithm (GA) are combined (called AGA) for the weights and thresholds of ENN optimization. …”
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