Artisanal and farmer bread making practices differently shape fungal species community composition in French sourdoughs by Michel, Elisa, Masson, Estelle, Bubbendorf, Sandrine, Lapicque, Léocadie, Nidelet, Thibault, Segond, Diego, Guézenec, Stéphane, Marlin, Thérèse, Devillers, Hugo, Rué, Olivier, Onno, Bernard, Legrand, Judith, Sicard, Delphine

“…Although industrialization led to the selection and spread of specific fermenting microbial strains, there are still ongoing artisanal processes that may allow the conservation of a wider species diversity and genetic diversity. We examined whether the diversity of artisanal practices could lead to an increased level in fungal species diversity for bread making. …”
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Variation in APOL1 Contributes to Ancestry-Level Differences in HDLc-Kidney Function Association by Amy Rebecca Bentley, Ayo P. Doumatey, Guanjie Chen, Hanxia Huang, Jie Zhou, Daniel Shriner, CongQing Jiang, Zhenjian Zhang, Guozheng Liu, Olufemi Fasanmade, Thomas Johnson, Johnnie Oli, Godfrey Okafor, Benjamin A. Eghan, Kofi Agyenim-Boateng, Jokotade Adeleye, Williams Balogun, Clement Adebamowo, Albert Amoah, Joseph Acheampong, Adebowale Adeyemo, Charles N. Rotimi

“…Given the APOL1 × HDLc interaction among AA, genetic factors may contribute to this paradoxical association. …”
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Exploration of the shared diagnostic genes and molecular mechanism between obesity and atherosclerosis via bioinformatic analysis by Wenrong An, Kegong Tang, Juan Liu, Wenfei Zheng, Guoxia Li, Yunsheng Xu

“…Abstract Obesity (OB) and atherosclerosis (AS) represent two highly prevalent and detrimental chronic diseases that are intricately linked. However, the shared genetic signatures and molecular pathways underlying these two conditions remain elusive. …”
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Retrieval of water quality parameters based on IOA-ML models and their response to short-term hydrometeorological factors by Wentong Hu, Donghao Miao, Chi Zhang, Zixian He, Wenquan Gu, Dongguo Shao

“…The best IOA-ML model for total phosphorus (TP), total nitrogen (TN), and permanganate index (CODMn) was extreme gradient boosting optimized by genetic algorithm (GA-XGB), while that for dissolved oxygen (DO) and turbidity was categorical boosting regression optimized by GA (GA-CBR). …”
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Advancing the Taxonomy of the Diatom <i>Pseudo-nitzschia</i> Through an Integrative Study Conducted in the Central and Southeastern Adriatic Sea by Tina Bonačić, Jasna Arapov, Ivana Bušelić, Ivana Lepen Pleić, Blanka Milić Roje, Tina Tomašević, Mia Bužančić, Marija Mladinić, Silvia Casabianca, Antonella Penna, Sanda Skejić, Živana Ninčević Gladan

“…Our findings underscore the value of a combined approach for reliable species identification and contribute to the development of genetic sequence databases that support the advancement of next-generation methods such as metabarcoding. …”
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Facilitation of Tumor Stroma-Targeted Therapy: Model Difficulty and Co-Culture Organoid Method by Qiu-Shi Feng, Xiao-Feng Shan, Vicky Yau, Zhi-Gang Cai, Shang Xie

“…PDTOs, derived from tumor tissues or cancer-specific stem cells, accurately mimic the tissue-specific and genetic features of primary tumors, making them valuable for drug screening. …”
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Oxidative stress-driven enhanced iron production and scavenging through Ferroportin reorientation worsens anemia in antimony-resistant Leishmania donovani infection. by Souradeepa Ghosh, Krishna Vamshi Chigicherla, Shirin Dasgupta, Yasuyuki Goto, Budhaditya Mukherjee

“…This antimony-unresponsiveness points towards a genetic adaptation that underpins LD-R's evolutionary persistence and dominance over sensitive counterparts (LD-S). …”
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Two-Stage Optimization Method for the Bearing Layout of Isolated Structure by Yu Dang, GenXiong Zhao, HongTu Tian, Guobao Li

“…The isolation devices are simplified as a kind of lead-rubber bearing. The genetic algorithm is used to find the optimal parameters of the isolated layer. …”
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Blue elixir of youth and wellness: The multicomponent-multitarget paradigm of Curcuma caesia Roxb by Sabrina Burattini, Federico Gianfanti, Francesco Onesimo, Sabrina Donati Zeppa, Barbara Canonico, Mariele Montanari, Giovanna Panza, Daniele Lopez, Giosuè Annibalini, Fabiana Fanelli, Roberta Saltarelli, Michele Mari, Michele Retini, Riham Osman, Aghna Mariam, Matteo Micucci, Giovanni Caprioli, Agnese Santanatoglia, Deborah Agostini, Michela Battistelli

“…Aging is a complex biological process influenced by genetic, environmental, and lifestyle factors, including diet and exercise. …”
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Template switching during DNA replication is a prevalent source of adaptive gene amplification by Julie N Chuong, Nadav Ben Nun, Ina Suresh, Julia Cano Matthews, Titir De, Grace Avecilla, Farah Abdul-Rahman, Nathan Brandt, Yoav Ram, David Gresham

“…Copy number variants (CNVs) are an important source of genetic variation underlying rapid adaptation and genome evolution. …”
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Evaluation of the Effectiveness of Multiple Machine Learning Methods in Remote Sensing Quantitative Retrieval of Suspended Matter Concentrations: A Case Study of Nansi Lake in Nort... by Xiuyu Liu, Zhen Zhang, Tao Jiang, Xuehua Li, Yanyi Li

“…Then, seven methods such as linear regression, BP neural network (BP), KNN, random forest (RF), and random forest based on genetic algorithm optimization (GA_RF) are used to construct the inversion model of TSM concentration. …”
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Integrating MAPK pathway inhibition into standard-of-care therapy for pediatric low-grade glioma by Erin E. Crotty, Aimee A. Sato, Aimee A. Sato, Mohamed S. Abdelbaki

“…Pediatric low-grade gliomas (pLGG) are a group of tumors largely driven by alterations in a single genetic pathway, known as the RAS-RAF-mitogen-activated protein kinase (MAPK) pathway. …”
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Rhipicephalus simus ticks: new hosts for phleboviruses by Samuel Munalula Munjita, Benjamin Mubemba, John Tembo, Mathew Bates, Sody Munsaka, Ala Tabor

“…Phylogenetic analysis positioned LSK-ZM-102022 in a distinct but lone lineage within tick phleboviruses basal to known species like brown dog tick phlebovirus and phlebovirus Antigone. Pair-wise genetic distance analysis revealed similar findings. …”
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Optimization of Irrigation and Fertilization in Maize–Soybean System Based on Coupled Water–Carbon–Nitrogen Interactions by Aizheng Yang, Shuyuan Luo, Yaowen Xu, Pingan Zhang, Zhenyi Sun, Kun Hu, Mo Li

“…A multi-objective optimization model, integrating experimental data and mechanistic insights, was constructed and refined using the NSGA-III genetic algorithm to identify the optimal water and nitrogen application ratios. …”
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Red Army Soldiers from Kalmykia in the Battles for Belarus: a Historical and Statistical Study by Sergey G. Ershov

“…When writing the article, a complex of various general scientific and special methods was used, including historical-genetic, historical-comparative, historical-typological, historical-systemic, and statistical methods. …”
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The Effect of IL-4 Gene Polymorphisms on Cytokine Production in Patients with Chronic Periodontitis and in Healthy Controls by Jirina Bartova, Petra Borilova Linhartova, Stepan Podzimek, Tatjana Janatova, Kazi Svobodova, Antonin Fassmann, Jana Duskova, Jaromir Belacek, Lydie Izakovicova Holla

“…Chronic periodontitis (CP) is an inflammatory disease of the teeth-supporting tissues in which genetic predisposition, dental plaque bacteria, and immune mechanisms all play important roles. …”
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The SERPINB4 gene mutation identified in twin patients with Crohn’s disease impaires the intestinal epithelial cell functions by Xiao-Mei Ouyang, Jun-Hui Lin, Ying Lin, Xian-Ling Zhao, Ya‐Ni Huo, Lai-Ying Liang, Yong-Dong Huang, Gui-Jing Xie, Peng Mi, Zhen-Yu Ye, Bayasi Guleng

“…To identify new targets related to the initiation of CD, we screened a pair of twins with CD, which is a rare phenomenon in the Chinese population, for genetic susceptibility factors. Whole-exome sequencing (WES) of these patients revealed a mutation in their SERPINB4 gene. …”
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NIPAL1 as a prognostic biomarker associated with pancreatic adenocarcinoma progression and immune infiltration by Youlong Zhu, Zongze Qi, Shaoqi Zu, Fangchao Yang, Yanming Wang, Lei Zhu, Xintong Li, Ruixue Li, Hong Zhu

“…Abstract Pancreatic adenocarcinoma (PAAD) is a highly malignant tumor in the digestive system, with an increasing incidence and mortality rate globally. Recent genetic studies have revealed that the abnormal expression and functional dysregulation of various genes are involved in the occurrence and progression of pancreatic cancer. …”
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A Review on Biosurfactant Applications in the Petroleum Industry by Wei Xi, Yuanye Ping, Masoome Agha Alikhani

“…Biosurfactants are synthesized by microbes; therefore, various genetic diversities of microorganisms provide the considerable capability to produce new types of biosurfactants, which can develop EOR technology. …”
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G Protein-Coupled Receptor 17 Inhibits Glucagon-like Peptide-1 Secretion via a Gi/o-Dependent Mechanism in Enteroendocrine Cells by Jason M. Conley, Alexander Jochim, Carmella Evans-Molina, Val J. Watts, Hongxia Ren

“…Here, we expressed the human GPR17 long isoform (hGPR17L) in GLUTag cells, a murine EEC line, and we used the GPR17 synthetic agonist MDL29,951 together with pharmacological probes and genetic approaches to quantitatively assess the contribution of GPR17 signaling to GLP-1 secretion. …”
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