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981
Enhancing detection of STEC in the meat industry: insights into virulence of priority STEC
Published 2025-02-01“…Screening food enrichment broths with classical genetic markers (stx, eae) can overestimate the presence of highly virulent STEC, causing needless disruption and costs for food producers. …”
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982
Advances in personalized gastroenterology and hepatology 2016
Published 2016-08-01“…Based on modern molecular, genetic, epigenetic microbiologic and biochemical analyses it is, on the one hand, possible to identify disease-related point mutations and single nucleotide polymorphisms in the context of genomewide association analyses (GWAS). …”
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983
Research on civil aircraft cockpit display interface availability considering multidimensional indicators clustering and reduction
Published 2024-12-01“…Secondly, to tackle the problem of filtering multidimensional indicator datasets supported by small samples, an indicator clustering reduction algorithm is proposed based on hierarchical clustering-rough set information entropy(HC-CEBARKNC) which compared to K-means clustering and genetic algorithm. Finally, the support vector machine(SVM) classification model was employed to verify performance and reliability of both algorithms. …”
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984
PROBLEMS OF STATE AND LEGAL ADMINISTRATION IN THE SPHERE OF FOREST SEED PRODUCTION
Published 2024-12-01“…The process of formation and development of the unified genetic and selection complex (UGSC) of forestry in Russia and the reasons for its subsequent degradation are covered. …”
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985
Clinical presentation, diagnosis and treatment of intrahepatic cholestasis of pregnancy
Published 2018-08-01“…The etiology and pathogenesis of ICP are related to disorders of bile acid metabolism caused by hormonal factors (elevation of estrogen and progesterone levels) and genetic predisposition. The leading clinical signs of ICP include pruritus and jaundice that develop most commonly in the third trimester of pregnancy, and characteristic changes of laboratory scores: increase in bile acid level (over 10 mcmol/l) and moderate elevation of transaminase activity. …”
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986
Ultrasound Radiogenomics-based Prediction Models for Gene Mutation Status in Breast Cancer
Published 2025-03-01“…These features, including shape, texture, and intensity variations, are correlated with specific genetic mutations such as TP53 and PIK3CA, critical for cancer progression and treatment response. …”
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987
Densely vascularized thick 3D tissue shows enhanced protein secretion constructed with intermittent positive pressure
Published 2025-02-01“…Furthermore, in vivo experiments showed that IPP-cultured cell sheets enhanced the secretion of Gaussian luciferase by genetically modified mesenchymal stem cells. These findings highlight the IPP method as a technique that simultaneously enables the thickening of planar tissues and the construction of vascular networks. …”
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988
Probing the potential of InDel polymorphisms on the molecular identification of cetaceans
Published 2023-04-01“… Studies with cetaceans using degraded samples have faced challenges for molecular identification based on the barcoding methodology and other sequencing techniques due to the fragmented nature of the genetic material found on these samples. In this article, we evaluated the use of insertion–deletion regions for the molecular identification of cetaceans. …”
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989
Natural selection and evolution: evolving concepts
Published 2024-05-01“…Current evolutionary models incorporate different adaptive and non-adaptive processes based on molecular genetic changes and how DNA is modified over time in unicellular species, or in germline versus somatic cells in metazoan species. …”
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990
Cancer stem cells in head and neck squamous cell carcinoma and its associated markers: A review
Published 2024-04-01“…Most theories evolve either intrinsic (genetic) or extrinsic factors like tobacco and alcoholism as the major cause of oral cancer in India. …”
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991
The mcpC mutant of Salmonella enteritidis exhibits attenuation and confers both immunogenicity and protective efficacy in mice
Published 2025-02-01“…The ΔmcpC offers strong immune protection in mice, providing a solid foundation for the development of genetically engineered attenuated live vaccines against SE.…”
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992
Identification of HOXA9 methylation as an epigenetic biomarker predicting prognosis and guiding treatment choice in acute myeloid leukemia
Published 2025-02-01“…HOXA overexpression caused by genetic alterations, such as KMT2A rearrangements, NUP98- fusions and FLT3-ITD mutations, is frequently identified in AML. …”
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993
First detection and molecular characterization of porcine epidemic diarrhea virus (PEDV) in India: evidence of a new variant in Karnataka
Published 2025-02-01“…This study reports the first clinical outbreak of PED in India, followed by the detection and genetic characterization of PED virus (PEDV) during 2022-23. …”
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994
Risk factors for ocular biological parameters in Chinese preschool children: a cohort study from the Beijing whole childhood eye study
Published 2025-02-01“…However, the influence of genetic, growth and development, and environmental factors on these metrics in Chinese preschool children remains unclear. …”
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995
Vehicle-routing problem for low-carbon cold chain logistics based on the idea of cost–benefit
Published 2025-01-01“…Then, a hybrid algorithm called local search genetic algorithm (LSGA) is proposed, which amalgamates the destroy-repair operator with GA algorithm. …”
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996
Non-canonical lysosomal lipolysis drives mobilization of adipose tissue energy stores with fasting
Published 2025-02-01“…We functionally tested lysosomal lipolysis with pharmacological and genetic approaches in mice and in murine and human adipocyte and adipose tissue explant culture, establishing dependency on lysosomal acid lipase (LIPA/LAL) and the microphthalmia/transcription factor E (MiT/TFE) family. …”
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997
Virus-inspired biogenic delivery system for advancing cancer therapy
Published 2025-03-01“…VLPs lack viral virulence, resulting from a viral genetic material deficiency. In vaccine research, Virus-mimic nanovesicles have been effectively verified against cancer via the immunogenicity and the pharmacological effect of drug molecules delivered to mediate an immune response in the body. …”
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998
Mechanisms of bacterial-to-host interaction and their disorders at inflammatory bowel diseases
Published 2014-11-01“…At IBD, all mechanisms providing interaction of bacterial cells with the host body are malfunc tioning to some extent, that, in combination to genetic predisposition to this disease, results in development of clinical symptoms and morphological changes.…”
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999
INTESTINAL MICROBIOME - A LEADING FACTOR IN HUMAN HEALTH AND DISEASES
Published 2018-08-01“…Based on modern molecular, genetic, epigenetic microbiologic and biochemical studies it is, on the one hand, possible to identify disease-related point mutations and single nucleotide polymorphisms within genome-wide association analyses (GWAS). …”
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1000
Autism common variants associated with white matter alterations at birth: cross-sectional fixel-based analyses of 221 European term-born neonates from the developing human connecto...
Published 2025-02-01“…Despite the condition having high heritability, the relationship between autism common genetic variants and WM changes during this period remains unclear. …”
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