AKR1D1*36 C>T (rs1872930) allelic variant is associated with variability of the CYP2C9 genotype predicted pharmacokinetics of ibuprofen enantiomers – a pilot study in healthy volun... by Kapedanovska Nestorovska Aleksandra, Jakjovski Krume, Naumovska Zorica, Sterjev Zoran, Geskovska Nadica Matevska, Mladenovska Kristina, Suturkova Ljubica, Dimovski Aleksandar

“…The correlation between CYP2C9 and AKR1D1 genetic profile and the PK parameters for S-(+) and R-(−)-IBP was evaluated. …”
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Dynamics of Salmonella Dublin infection and antimicrobial resistance in a dairy herd endemic to salmonellosis. by Victor Santos do Amarante, Joelma Kellen de Castro Pereira, Matheus Ferreira Serafini, Carolina Pantuzza Ramos, Isabela Pádua Zanon, Thayanne Gabryelle Viana de Souza, Tiago Facury Moreira, Antônio Ultimo de Carvalho, Rodrigo Melo Meneses, Flavia Figueira Aburjaile, Vasco Azevedo, Elias Jorge Facury Filho, Rodrigo Otávio Silveira Silva

“…Dublin on a farm with a history of outbreaks, to understand the dynamics of the infection, characterize the antimicrobial resistance of the isolates, and evaluate their genetic similarity. Multiparous cows in the postpartum phase are nearly five times more likely to shed Salmonella sp. …”
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Study on Global Parameters Optimization of Dual-Drive Powertrain System of Pure Electric Vehicle Based on Multiple Condition Computer Simulation by Yong Wang, Hongguo Cai, Yinghua Liao, Jun Gao

“…As for such differences, this paper adopts intelligent algorithm to design the parameters of the transmission system and introduces the genetic algorithm into the optimization design of parameters to obtain the optimal vital parameters of the power transmission system based on computer simulation. …”
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Research on the Prediction of the Water Demand of Construction Engineering Based on the BP Neural Network by Hao Peng, Han Wu, Junwu Wang

“…However, the errors of the BP neural network model, the BP neural network improved by genetic algorithm, and the pluralistic return were larger. …”
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Arrhythmogenic right ventricular cardiomyopathy - What Is New since 2023 European Society of Cardiology Guidelines? Current Knowledge, Literature Review by Magdalena Balwierz

“… Introduction: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetically conditioned disease, characterized by gradual fibro-fatty replacement of myocardium and tendency to ventricular arrhythmias and heart failure. …”
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Impact of heat stress on growth and physiological parameters of soybean varieties at the seedling stage by Bashir Hassan, Samanhudi, Parjanto, Setyawati Andriyana, Komariah, Senge Masateru, Rahayu Muji, Salma Fathin Tilmiidzah

“…This study provides valuable insights into soybean heat stress tolerance mechanisms and identifies promising genetic resources for breeding heat-resilient cultivars in Indonesia. …”
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Structural Predictive Model of Presenilin-2 Protein and Analysis of Structural Effects of Familial Alzheimer’s Disease Mutations by Alejandro Soto-Ospina, Pedronel Araque Marín, Gabriel de Jesús Bedoya, Andrés Villegas Lanau

“…Alzheimer’s disease manifests itself in brain tissue by neuronal death, due to aggregation of β-amyloid, produced by senile plaques, and hyperphosphorylation of the tau protein, which produces neurofibrillary tangles. One of the genetic markers of the disease is the gene that translates the presenilin-2 protein, which has mutations that favor the appearance of the disease and has no reported crystallographic structure. …”
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Appearance of L90I and N205S Mutations in Effector Domain of NS1 Gene of pdm (09) H1N1 Virus from India during 2009–2013 by Sachin Kumar, Shashi Khare, Bano Saidullah, Inderjeet Gandhoke, Hanu Ram, Supriya Singh, L. S. Chauhan, Arvind Rai

“…Phylogenetic analysis of available NS1 sequences from India has grouped all the sequences into four clusters with mean genetic distance ranging from 12% to 24% between the clusters. …”
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Nidoviruses associated with aquatic animals by L. P. Buchatsky, V. V. Makarov

“…Nidoviruses comprise the most complex grouping among other viruses with respect to their multiplicity, phylogeny, systematics, species identification, genetic relationships within a taxon, progressive variability. …”
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Biosemiotic Foundations of a Darwinian Approach to Cultural Evolution by Herrmann-Pillath Carsten

“…First, they employ an inflationary generic concept of culture that covers all information that is stored and transmitted non-genetically; this differs from the narrower uses in the humanities that focus on the diversity of cultures and their interactions. …”
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Recombinant AAV batch profiling by nanopore sequencing elucidates product-related DNA impurities and vector genome length distribution by Florian Dunker-Seidler, Kathrin Breunig, Magdalena Haubner, Florian Sonntag, Markus Hörer, Rebecca C. Feiner

“…During production, recombinant adeno-associated virus (rAAV) capsids are equipped with heterogeneous genetic payloads including undesired DNA impurities as well as truncated vector genomes. …”
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Differences in Transcriptional Activation by the Two Allelic (L162V Polymorphic) Variants of PPARα after Omega-3 Fatty Acids Treatment by Iwona Rudkowska, Mélanie Verreault, Olivier Barbier, Marie-Claude Vohl

“…Omega-3 fatty acids (FAs) have the potential to regulate gene expression via the peroxisome proliferator-activated receptor α (PPARα); therefore, genetic variations in this gene may impact its transcriptional activity on target genes. …”
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Coping with the Forced Swim Stressor: Towards Understanding an Adaptive Mechanism by E. R. de Kloet, M. L. Molendijk

“…In the past decade however the switch from active to passive “coping” was used increasingly to describe the phenotype of an animal that has been exposed to a stressful history and/or genetic modification. A PubMed analysis revealed that in a rapidly increasing number of papers (currently more than 2,000) stress-related immobility in the FST is labeled as a depression-like phenotype. …”
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Molecular Diversity of Arbuscular Mycorrhizal Fungi (AMF) Associated with Carissa edulis, an Endangered Plant Species along Lake Victoria Basin of Kenya by Benard O. Ogoma, Stephen F. Omondi, Jane Ngaira, Josephine W. Kimani

“…This study evaluated the genetic diversity of AMF associated with the roots of C. edulis within Lake Victoria basin ecosystem of Kenya. …”
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Altered microbiome and metabolome profiling in fearful companion dogs: An exploratory study. by Luigi Sacchettino, Michele Costanzo, Iolanda Veneruso, Valeria D'Argenio, Maria Mayer, Francesco Napolitano, Danila d'Angelo

“…Such a dysfunctional behavior can be associated with genetic susceptibility, environmental factors, traumatic experiences, and medical conditions. …”
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The Constitution as an Object of Political Analysis by Vasily K. Belozerov

“…The possibility of discovering evidence of the nation’s identity in the constitution, as well as a solid genetic relationship between the present and the past and future, is critical to comprehending its political relevance. …”
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Comparative Transcriptome Analysis Reveals Molecular Defensive Mechanism of Arachis hypogaea in Response to Salt Stress by Hao Zhang, Xiaobo Zhao, Quanxi Sun, Caixia Yan, Juan Wang, Cuiling Yuan, Chunjuan Li, Shihua Shan, Fengzhen Liu

“…Taken together, the identification of DEGs’ response to salt tolerance of cultivated peanut will provide a solid foundation for improving salt-tolerant peanut genetic manipulation in the future.…”
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Situational analysis on porcine diseases of priority to pig industry: methods for biosecurity improvement in the Russian Federation holdings by A. S. Oganesyan, M. A. Shibayev, O. N. Petrova, N. Ye. Baskakova, A. K. Karaulov

“…Based on the discussion results, automation and digitalization of all processes in pig industry, generation of genetically modified pigs not susceptible to the most significant pathogens such as African swine fever, classical swine fever, porcine reproductive and respiratory syndrome viruses and their use for production purposes, further research and implementation of integrated technological solutions for feed sanitation have been concluded to be the evolutionarily significant ways for effective pig farming intensification in the Russian Federation.…”
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Toward Pleomorphic Reconfigurable Robots for Optimum Coverage by S. M. Bhagya P. Samarakoon, M. A. Viraj J. Muthugala, Mohan R. Elara, Selva kumaran

“…The optimum size for reconfiguration is determined by the genetic algorithm based on the arrangement of the environment. …”
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Serum Transthyretin Level as a Plausible Marker for Diagnosis of Child Acute Malnutrition by Behailu Tsegaye, Amha Mekasha, Solomon Genet

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