Multidisciplinary approach to functional somatic syndromes: study protocol for a population-based prospective cohort study by Hamidreza Roohafza, Harold Snieder, Fatemeh Hadizadeh, Peyman Adibi, Alireza Ani, Ahmad Vaez

“…Introduction Isfahan functional disorders (ISFUN) cohort study aims to describe the interplay of genetic and environmental factors in shaping the characteristics of functional somatic syndromes (FSS). …”
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Case report: A novel 11-bp deletion in exon 11 causing a frameshift in the C-terminal of the ALAS2 gene leading to X-linked sideroblastic anemia—a family study by Salam Al kindi, Salam Al kindi, Altaf Al-Mamari, Shoaib Al-Zadjali, Mohamed Al-Rawahi, Ali Al Madhani, Anil V. Pathare

“…X-linked sideroblastic anemia (XLSA) (MIM 300752) is the most common genetic form of sideroblastic anemia, a heterogeneous group of disorders characterized by iron deposits in the mitochondria of erythroid precursors. …”
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Biodiversity futures: digital approaches to knowledge and conservation of biological diversity by H. Freitas, H. Freitas, A. C. Gouveia, A. C. Gouveia

“…<p>Biodiversity, encompassing species diversity, genetic resources, and ecosystems, is essential for human well-being and quality of life. …”
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Trichostatin A suppresses hearing loss by reducing oxidative stress and inflammation in an Alport syndrome model. by Yoon Seok Nam, Eun-Ji Gi, Yoo-Seung Ko, Sungsu Lee, Hyong-Ho Cho

“…Alport syndrome (AS) is a genetic disorder marked by mutations in type IV collagen, leading to kidney glomerular dysfunction. …”
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Association of ANKRD55 Gene Polymorphism with HT: A Protective Factor for Disease Susceptibility by Yu-die Fang, Jing Zhao, Xin-juan Zhuang, Jian-bin Xu, Tian-tian Cai, Xiao-rong Yang, Kai-da Mu, Jin-an Zhang

“…The results showed that the allele frequencies of rs7731626 and rs159572 loci in HT patients were lower than those in normal controls (P=0.048 and P=0.03, respectively). In different genetic model analyses, rs7731626 and rs159572 were also significantly correlated with HT in allele, dominant and additive models before and after age and sex adjustment. …”
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Case report: A panorama gene profile of ovarian cancer metastasized to axillary lymph node by Yu Xia, Yu Huang, Zheng Liu, Siyuan Song, Yi Wang, Yi Wang, Jing Luo

“…This study unraveled the potential mechanism of genetic mutation for tumor metabolism, drug resistance, and metastasis.…”
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Geographical distribution of eight neuromuscular disorders in the Netherlands based on a nationwide registry by Johanna C.W. Deenen, André L.M. Verbeek, Pieter A. van Doorn, Catharina G. Faber, Anneke J. van der Kooi, Nicolette C. Notermans, Jan J.G.M. Verschuuren, Baziel G.M. van Engelen, Nicol C. Voermans

“…Geographical mapping of the specific disorders is expected to provide valuable insights into clustering of the conditions, which points to possible environmental and genetical determinants. So far, mostly geographical maps of motor neuron diseases have been reported. …”
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Proteome-wide mendelian randomization identifies causal plasma proteins in interstitial lung disease by Kunrong Yu, Wanying Li, Wenjie Long, Yijia Li, Yanting Li, Huili Liao, Jianhong Liu

“…Our study identified eight plasma proteins genetically associated with ILD or its subtypes. Among these, three proteins—CDH15 (Cadherin-15), LTBR (Lymphotoxin-beta receptor), and ADAM15 (A disintegrin and metalloproteinase 15)—emerged as priority biomarkers and potential therapeutic targets, demonstrating more reliable associations by passing a series of sensitivity analyses compared to the others. …”
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Production of all-triploid derived from gynogenetic homologous diploid crucian carp (♀) × diploid red crucian carp (♂) by Chongqing Wang, Yan Tang, Xiang Luo, Yuxin Zhang, Yue Zhou, Qingwen Xiao, Zhengkun Liu, Xinyi Deng, Xu Huang, Xidan Xu, Xiaowei Xu, Kun Zhang, Qinbo Qin, Shaojun Liu

“…All 3nRR possessed 150 chromosomes and were triploid hybrids. The genetic characteristics of 5S rDNA in 3nRR individuals and their parental counterparts, as well as the measurable and countable traits, were explored. …”
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Complete genome sequence of Pseudarthrobacter sp. NIBRBAC000502770 from coal mine of Hongcheon on Republic of Korea by Min-Kyu Park, Yeong-Jun Park, Myung-Suk Kang, Min-Ha Kim, Soo-Young Kim, Jae-Ho Shin

“…The objective was to explore the strain's genetic potential for plant growth promotion and heavy metal resistance, particularly arsenate and copper. …”
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Security protection method based on mimic defense and Paillier encryption for smart IoT terminals by GU Tiansheng, ZENG Fukang, SHAO Sisi, NIE Yijun, JI Zongkai, ZHENG Yulu, SHI Yuchen, LIU Shangdong, JI Yimu

“…First, a security architecture was constructed based on the mimic defense theory to ensure the reliability and robustness of the system even when the edge domain smart terminal had its own security genetic defects. Then, a secure blind signature with Paillier encryption (SBSPE) algorithm was designed in this architecture to safeguard the data and privacy of the edge-area smart terminals throughout the data processing lifecycle of edge-area smart terminals. …”
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Drug repurposing screen for the rare disease ataxia-telangiectasia by Namrata Jayanth, Gurvan Mahé, Matthew Campbell, Mike Lipkin, Shushant Jain, Rhea van de Bospoort, Jennifer Thornton, Brad Margus, David F. Fischer

“…Ataxia Telangiectasia (A-T) is a rare, autosomal recessive genetic disorder characterized by a variety of symptoms, including progressive neurodegeneration, telangiectasia, immunodeficiency, and an increased susceptibility to cancer. …”
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An epigenetic memory at the CYP1A gene in cancer-resistant, pollution-adapted killifish by Samantha Carrothers, Rafael Trevisan, Nishad Jayasundara, Nicole Pelletier, Emma Weeks, Joel N. Meyer, Richard Di Giulio, Caren Weinhouse

“…However, PAH-tolerant fish reared in clean water recover CYP1A inducibility, indicating a non-genetic effect. We observed epigenetic control of this reversible memory of generational PAH stress in F1 PAH-tolerant embryos. …”
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The Most Important Risk Factors Among Angina Patients in Thi-Qar Governorate in Iraq by Amel Mustafa Kamil, Mohammed Munis Dakheel, Tehsen Ali Kadhem

“…However, no significant impacts of the genetic, smoking, alcohol and obesity were found as risk factors. …”
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Anther transcriptomes in cold-tolerant rice cultivars tend to show insensitive responses by Koichi Yamamori, Seiya Ishiguro, Kei Ogasawara, Kayyis Muayadah Lubba, Kaien Fujino, Kazumitsu Onishi, Yutaka Sato, Yuji Kishima

“…From the few cloned genes, it is difficult to genetically interpret intermediate tolerance or susceptibility levels and explain the complexity of stress responses and tolerance. …”
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Healthcare-associated infections caused by Candida spp. in critical infants: a look at environmental surfaces by Priscila Guerino Vilela, Isadora Caixeta da Silveira Ferreira, Ralciane de Paula Menezes, Mário Paulo Amante Penatti, Reginaldo dos Santos Pedroso, Denise Von Dolinger de Brito Röder

“…All isolates produced biofilm. A notable genetic similarity was observed between some environmental and clinical isolates, suggesting the environment as a possible source of infection.…”
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46,XY Disorder of Sex Development Caused by 17α-Hydroxylase/17,20-Lyase Deficiency due to Homozygous Mutation of CYP17A1 Gene: Consequences of Late Diagnosis by Giampaolo Papi, Rosa Maria Paragliola, Paola Concolino, Carlo Di Donato, Alfredo Pontecorvi, Salvatore Maria Corsello

“…Laboratory, imaging, and genetic features are herein reported and discussed.…”
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Paracrine Mechanisms of Mesenchymal Stromal Cells in Angiogenesis by Selma Maacha, Heba Sidahmed, Shana Jacob, Giusy Gentilcore, Rita Calzone, Jean-Charles Grivel, Chiara Cugno

“…The secretome is a composite product secreted by MSC in vitro (in conditioned medium) and in vivo (in the extracellular milieu), consisting of a protein soluble fraction (mostly growth factors and cytokines) and a vesicular component, extracellular vesicles (EVs), which transfer proteins, lipids, and genetic material. MSC-derived secretome differs based on the tissue from which the MSCs are isolated and under specific conditions (e.g., preconditioning or priming) suggesting that clinical applications should be tailored by choosing the tissue of origin and a priming regimen to specifically correct a given pathology. …”
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Microscopical and molecular investigation of Ichthyophthirius multifiliis from fish in Mosul city, Iraq by Esraa A. Altaie, Nadia N. Alhayali

“…Molecular phylogenetic analysis conducted with 18S rRNA gene confirming species identification of one positive isolate out of 13 belonging to the ectoparasite I. multifiliis under the accession number PQ012981 and according to the genetic tree analysis of I. multifiliis showed 100% match with each of the United States isolates for the same species and under the accession numbers KJ690571, KJ690572, KJ690570, KJ690568, KJ690567, KJ690566 and KJ690565 and isolates OM865867 in India and OM302501 in China. …”
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Management of Major Seed-Borne Fungi of Cowpea (Vigna unguiculata (L.) Walp) with Four Selected Botanical Extracts by Eric Gyasi, Daniel A. Kotey, Barnabas A. Adongo, Fuleratu K. Adams, Edmund O. Owusu, Abdul Mohammed

“…This study aimed to identify seed-borne fungi on 200 accessions of cowpea under cold storage at CSIR-Plant Genetic Resources Research Institute (PGRRI), Ghana. …”
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