A rare case of adult-onset vanishing white matter leukoencephalopathy with movement disorder, expressing homozygous EIF2B3 and PRKN pathogenic variants by Bashar Kamal Ali Douden, Yazan Mohammad Abdullah Abufara, Mahmood Fayez Ali Aldrabeeh, Naela Ramadan Mohammad Tell, Ismail Abudaya

“…The diagnosis of adult-onset VWML with movement disability was substantiated by genetic testing, which named a homozygous pathogenic missense variant, EIF2B3, and a deletion in PRKN/PARK2. …”
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Prediction of time-dependent bearing capacity of concrete pile in cohesive soil using optimized relevance vector machine and long short-term memory models by Jitendra Khatti, Mohammadreza Khanmohammadi, Yewuhalashet Fissha

“…Each SRVM model has been optimized by each genetic (GA_SRVM) and particle swarm optimization (PSO_RVM) algorithm. …”
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Germline variants of the genes involved in NF-kB activation are associated with the risk of COPD and lung cancer development by Baranasic Jurica, Niazi Yasmeen, Chattopadhyay Subhayan, Rumora Lada, Ćorak Lorna, Dugac Andrea Vukić, Jakopović Marko, Samaržija Miroslav, Försti Asta, Knežević Jelena

“…However, not all smokers develop the disease, indicating that genetic susceptibility could be important. Therefore, the aim of this study was to search for the potential overlapping genetic biomarkers, with a focus on single nucleotide polymorphisms (SNPs) located in the regulatory regions of immune-related genes. …”
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Exploring the genotypic potential of perilla (Perilla frutescens L.) for climate-resilient agriculture in the North Eastern Himalayas by Meraj Alam Ansari, Meraj Alam Ansari, Amit Kumar, T. P. Ahammed Shabeer, Alok Kumar, Subhra Saikat Roy, Subhra Saikat Roy, Majhrool Hak Ansari, Raghavendra Singh, Raghavendra Singh, Moirangthem Sangeeta, Jayanta Layek, Narendra Prakash, Vinay K. Mishra

“…To dissect the genetic basis, we evaluated 28 diverse genotypes of perilla across three growing seasons for eight agronomic traits and 16 biochemical traits, which revealed substantial phenotypic and biochemical variation. …”
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Agronomic Performance of Irrigated and Rainfed Arabica Coffee Cultivars in the Cerrado Mineiro Region by Giovani Belutti Voltolini, Gladyston Rodrigues Carvalho, Vinícius Teixeira Andrade, André Dominghetti Ferreira, Francislei Vitti Raposo, João Paulo Felicori Carvalho, Diego Junior Martins Vilela, Cleidson Alves da Silva, Jéfferson de Oliveira Costa, Guilherme Barbosa Abreu, Juliana Costa de Rezende Abrahão, César Elias Botelho, Denis Henrique Silva Nadaleti, Marcelo Ribeiro Malta, Vânia Aparecida Silva, Sônia Maria de Lima Salgado, Reginério Soares de Faria, Antônio Carlos Baião de Oliveira, Antônio Alves Pereira

“…Coffee genetic improvement programs have been evolving very quickly, with frequent launches of new cultivars. …”
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Alterations in DNA Damage Repair Genes Before and After Neoadjuvant Cisplatin-based Chemotherapy in Muscle-invasive Bladder Cancer by Ursula Lemberger, Büsra Ernhofer, Sigurd Krieger, Andreas Bruchbacher, André Oszwald, Ekaterina Laukhtina, Andrea Haitl, Melanie R. Hassler, Bernhard Englinger, Eva Compérat, Shahrokh F. Shariat

“…Background and objective: The role of genetic variants in response to systemic therapy in muscle-invasive bladder cancer (MIBC) is still elusive. …”
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The Status of Wild Grapevine (<i>Vitis vinifera</i> L. subsp. <i>sylvestris</i> (C.C. Gmel.) Hegi) Populations in Georgia (South Caucasus) by Gabriele Cola, Gabriella De Lorenzis, Osvaldo Failla, Nikoloz Kvaliashvili, Shengeli Kikilashvili, Maia Kikvadze, Londa Mamasakhlisashvili, Irma Mdinaradze, Ramaz Chipashvili, David Maghradze

“…Therefore, we believe it is urgent for Georgia to implement specific protection measures to preserve this vital genetic resource.…”
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SCN10A gene polymorphism is associated with pain sensitivity and postoperative analgesic effects in patients undergoing gynecological laparoscopy by Yang Gao, Jing Li, Lin Gan, Meng Cai, Xiaofeng Lei, Jin Yu

“…Abstract Background Postoperative pain intensity is influenced by various factors, including genetic variations. The SCN10A gene encodes the Nav1.8 sodium channel protein, which is crucial for pain signal transmission in peripheral sensory neurons. …”
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Antimicrobials profiling, biofilm formation, and clonal lineage of methicillin-resistant Staphylococcus aureus isolated from cockroaches by Yasin Saberi, Mehrdad Halaji, Mohsen Karami, Jalal Jafarzadeh, Kasra Javadi, Hoda Shirafkan, Abazar Pournajaf

“…This study aims to investigate the antibiotic resistance patterns, biofilm formation, and genetic characteristics of S. aureus isolated from cockroaches in hospital environments. …”
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Hepatitis B Virus-KMT2B Integration Drives Hepatic Oncogenic Processes in a Human Gene-edited Induced Pluripotent Stem Cells-derived ModelSummary by Jun Tsuchiya, Masato Miyoshi, Sei Kakinuma, Fukiko Kawai-Kitahata, Akihide Kamiya, Taro Shimizu, Ayako Sato, Keiya Watakabe, Tomohiro Mochida, Kento Inada, Rion Kamimae, Shun Kaneko, Miyako Murakawa, Sayuri Nitta, Mina Nakagawa, Mamoru Watanabe, Yasuhiro Asahina, Ryuichi Okamoto

“…Methods: Based on the genetic information on HBV-KMT2B integration in HCC, we determined its complete DNA sequence and transcript variants. …”
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Association of MTHFD1 G1958A (rs2236225) gene polymorphism with the risk of congenital heart disease: a systematic review and meta-analysis by Kang Yi, Shao-E He, Tao Guo, Zi-Qiang Wang, Xin Zhang, Jian-Guo Xu, Hao-Yue Zhang, Wei-Guo Liu, Tao You

“…In maternal analysis, 2 genetic models of MTHFD1-G1958A polymorphism increased the risk of CHD: the heterozygote model (GA vs. …”
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Mesenchymal stromal cells promote the formation of lung cancer organoids via Kindlin-2 by Zhilin Sui, Xianxian Wu, Jiaxin Wang, ShihJye Tan, Chao Zhao, Zhentao Yu, Chuanyue Wu, Xiaoxiao Wang, Ling Guo

“…We evaluated whether LCOs co-cultured with fibroblast retained the original genetic mutations of their source tumors based on WES. …”
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Development of Primer Panels for Whole-Genome Amplification and Sequencing of Human Seasonal Coronaviruses: hCoV-OC43, hCoV-HKU1, hCoV-229E, and hCoV-NL63 by Tamila Musaeva, Artem Fadeev, Maria Pisareva, Veronika Eder, Andrey Ksenafontov, Margarita Korzhanova, Valery Tsvetkov, Alexander Perederiy, Irina Kiseleva, Daria Danilenko, Dmitry Lioznov, Andrey Komissarov

“…While seasonal patterns and the annual variability of predominant hCoV species are well-documented, their genetic and species diversity in St. Petersburg and across Russia remains largely unexplored. …”
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First genome-scale insights into the virulence of the snow mold causal fungus Microdochium nivale by Ivan Tsers, Ekaterina Marenina, Azat Meshcherov, Olga Petrova, Olga Gogoleva, Alexander Tkachenko, Natalia Gogoleva, Yuri Gogolev, Evgenii Potapenko, Olga Muraeva, Mira Ponomareva, Viktor Korzun, Vladimir Gorshkov

“…To better understand the genetic potential of M. nivale and to obtain a convenient reference for transcriptomic studies on this species, the identified genes were annotated and split into hierarchical three-level functional categories. …”
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Causal relationships between air pollution and common autoimmune diseases: a two-sample Mendelian randomization study by Ming Zhang, Yidian Wang, Shouye Hu, Yue Wu

“…Abstract Air pollution is strongly associated with autoimmune diseases (ADs), however, the genetic causality between them remains poorly understood. …”
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Morphology, phylogeography, phylogeny, and taxonomy of Cyclorhiza (Apiaceae) by Bo-Ni Song, Xueyimu Aou, Rong-Ming Tian, Jing Cai, Wei-Yan Tan, Chang-Kun Liu, Chang-Kun Liu, Xing-Jin He, Song-Dong Zhou

“…The genus possessed high genetic diversity and significant lineage geographic structure, which may be associated with the long-term evolutionary history, complex terrain and habitat, and its sexual reproduction mode. …”
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FROST RESISTANCE OF NEW PEACH FORMS IN THE COLLECTION OF NIKITSKY BOTANICAL GARDENS by E. I. Bunchuk

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WILD RELATIVES OF CULTIVATED PLANTS IN THE TERRITORY OF THE PRYAZOVSKY STATE NATURAL RESERVE by O. V. Zelenskaya, V. V. Korunchikova

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Weal and woe of interleukin-18 in the T cell therapy of cancer by Christoph Kessel, Hinrich Abken, Claudia Rossig

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Segunda parte. Desenmascarando al imitador: neumonía por citomegalovirus que inicia como CVID se diagnostica como deficiencia de GATA2 con dos mutaciones patológicas únicas by Andrés F. Zea-Vera, Mónica Fernandes-Pineda

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