A New Metaheuristic-Based Hierarchical Clustering Algorithm for Software Modularization by Masoud Aghdasifam, Habib Izadkhah, Ayaz Isazadeh

“…Due to the NP hardness of the clustering problem, evolutionary approaches such as the genetic algorithm have been used to solve this problem. …”
Get full text

Three decades of research efforts on the uses, conservation, and management of Cola nitida (Vent.): State of knowledge and prospects in Africa by Tokannou Isabelle E.T., Sanogo Souleymane, Houndonougbo Juliano S.H., Salako Kolawolé Valère, Fandohan Adandé Belarmain

“…Several studies were focused on the socio-economic importance of the species (n = 139 ~ 50%), nutritional and chemical properties of its organs (n = 48 ~ 17%), improvement of its propagation methods (n = 30 ~ 11%), pest and pesticide control (n = 39 ~ 14%), morphological and genetic diversity (n = 21 ~ 7.5%), its botanical description and ecology (n = 2 ~ 0.7%), and climate change threats on the species (n = 1 ~ 0.3%). …”
Get full text

Prognostic factors in hereditary breast cancer: A review by Ziske Maritska, Sarmoko

“…The response to chemotherapy, especially platinum-based drugs, is influenced by genetic mutations such as TP53 and PTEN, which are common in TNBC. …”
Get full text

Comparative analysis of selected methods of carbapenemase determination among clinical Klebsiella pneumoniae. by Agata Pruss, Alicja Skierska, Paweł Kwiatkowski, Helena Masiuk, Joanna Jursa-Kulesza, Stefania Giedrys-Kalemba, Iwona Bilska, Monika Sienkiewicz, Maria V Melnyk, Barbara Dołęgowska

“…The production of carbapenemases was assessed using phenotypic and genetic methods. The strains tested showed complete resistance to most beta-lactams and varying sensitivity to drugs from the quinolone carbapenem group and aminoglycosides. …”
Get full text

A Case of Noncompaction at All Segments of Both Right and Left Ventricles by Ali Pourmoghaddas, Reihaneh Zavar, Mohaddeseh Behjati

“…Extensive sinusoid formation and trabeculation of RV and nearby all LV segments and its association with mental retardation suggest presence of strong genetic background.…”
Get full text

Single Nucleotide Polymorphisms in IFN-γ Signaling Pathway Associated with Risk of Hepatitis B Virus Infection in Chinese Children by Yang Zhuo, Yalan Yang, Mingjun Zhang, Ying Xu, Zhongping Chen, Lihong Mu, Xiaojun Tang, Zhaohui Zhong, Juan Chen, Li Zhou

“…Our study confirmed that genetic variants in IFN-γ signaling pathway have significant associations with HBV infection, especially with HBV breakthrough in children. …”
Get full text

DNA Methylation Profiles of Blood Cells Are Distinct between Early-Onset Obese and Control Individuals by Je-Keun Rhee, Jin-Hee Lee, Hae Kyung Yang, Tae-Min Kim, Kun-Ho Yoon

“…Obesity is a highly prevalent, chronic disorder that has been increasing in incidence in young patients. Both epigenetic and genetic aberrations may play a role in the pathogenesis of obesity. …”
Get full text

Serum Matrix Metalloproteinase-3 in Comparison with Acute Phase Proteins as a Marker of Disease Activity and Radiographic Damage in Early Rheumatoid Arthritis by Mahmood M. T. M. Ally, Bridget Hodkinson, Pieter W. A. Meyer, Eustasius Musenge, Mohammed Tikly, Ronald Anderson

“…Matrix metalloproteinase-3 (MMP-3) is involved in the immunopathogenesis of rheumatoid arthritis (RA), but little is known about its relationship to genetic susceptibility and biomarkers of disease activity, especially acute phase reactants in early RA. …”
Get full text

Deep imaging of LepR+ stromal cells in optically cleared murine bone hemisections by Yuehan Ni, Jiamiao Wu, Fengqi Liu, Yating Yi, Xiangjiao Meng, Xiang Gao, Luyi Xiao, Weiwei Zhou, Zexi Chen, Peng Chu, Dan Xing, Ye Yuan, Donghui Ding, Ge Shen, Min Yang, Ronjie Wu, Ling Wang, Luiza Martins Nascentes Melo, Sien Lin, Xiaoguang Cheng, Gang Li, Alpaslan Tasdogan, Jessalyn M. Ubellacker, Hu Zhao, Shentong Fang, Bo Shen

“…Completed within approximately 12 days, this process yields highly transparent tissues that maintain genetically encoded or antibody-stained fluorescent signals. …”
Get full text

Bacterial Toxin Fusion Proteins Elicit Mucosal Immunity against a Foot-and-Mouth Disease Virus Antigen When Administered Intranasally to Guinea Pigs by Sreerupa Challa, Steven M. Szczepanek, Debra Rood, Roger W. Barrette, Lawrence K. Silbart

“…In the current study, two different carrier/adjuvant approaches were used to augment mucosal immunity to the FMDV O1 BFS G-H loop epitope, in which the G-H loop was genetically coupled to the E. coli LT-B subunit and coexpressed with the LTA2 fragment (LTA2B-GH), or the nontoxic pseudomonas exotoxin A (ntPE) was fused to LTA2B-GH at LT-A2 to enhance receptor targeting. …”
Get full text

The Prognostic Implication of the BRAF V600E Mutation in Papillary Thyroid Cancer in a Chinese Population by Ziheng Ye, Xiaotian Xia, Peipei Xu, Wenfei Liu, Shoufei Wang, Youben Fan, Minggao Guo

“…The BRAF V600E mutation is an important genetic event in papillary thyroid cancer (PTC). This study aimed to provide additional information regarding the association of the BRAF V600E mutation with PTC prognosis. …”
Get full text

Mendelian randomization study of serum uric acid levels and urate-lowering drugs on pulmonary arterial hypertension outcomes by Xiaoling Yao, Xin Cai, Shaoqin Zhang, Yuzheng Yang, Xiangyan Yang, Wukai Ma, Zong Jiang

“…This study establishes a genetic basis for a causal link between serum uric acid levels and PAH. …”
Get full text

An interval Type-2 fuzzy Fractional-Order PD-PI controller for frequency stabilization of islanded microgrids optimized with CO algorithm by Siavash Shirali, Saeed Zolfaghari Moghaddam, Mortaza Aliasghary

“…Additionally, optimizing the controller parameters in dynamic systems is another critical issue, where traditional algorithms such as genetic algorithm (GA), particle swarm optimization (PSO), and sine cosine algorithm (SCA) often struggle with premature convergence and suboptimal solutions. …”
Get full text

Platelet Responses in Cardiovascular Disease: Sex-Related Differences in Nutritional and Pharmacological Interventions by Valeria Gasperi, M. Valeria Catani, Isabella Savini

“…Cardiovascular diseases (CVD) represent one of the biggest causes of death globally, and their prevalence, aetiology, and outcome are related to genetic, metabolic, and environmental factors, among which sex- and age-dependent differences may play a key role. …”
Get full text

Automation-aided construction and characterization of Bacillus subtilis PrsA strains for the secretion of amylases by Felix Hamburger, Niels Schlichting, Michael Eichenlaub, Paul Igor Costea, Christopher Sauer, Stefan Jenewein, Johannes Kabisch, Johannes Kabisch

“…In addition to providing the key learnings from the workflow, it was revealed that no single PrsA molecule consistently improved amylase production, but genetic constructs combining different elements showed up to a 10-fold variation in yield. …”
Get full text

Familial Pulmonary Capillary Hemangiomatosis Early in Life by Johannes Wirbelauer, Helge Hebestreit, Alexander Marx, Eugene J. Mark, Christian P. Speer

“…Despite the differences in clinical course, the trias of PCH, PDA, and pulmonary hypertension in the two life born girls suggests a genetic background.…”
Get full text

PENANGANAN JERAWAT SINDROM AKUMULASI DAHAK MENGGUNAKAN AKUPUNTUR DAN HERBAL JIANGHUANG by Dyah Agesti, Suryani Dyah Astuti, Arifa Mustika

“…Acne is clinically affected by an increase in sebum, Propionibacterium bacteria acne, hormones, genetic, stress, diet and the environment. In Chinese Medicine, acne vulgaris belongs to categories of Feng Ci, it is caused by wind-heat pathogens that attack the lungs and excessive consumption of spicy and oily foods resulting in accumulation of heat in the stomach and intestines. …”
Get full text

Complete Genome Sequence of the Plant Growth-Promoting Bacterium Hartmannibacter diazotrophicus Strain E19T by Christian Suarez, Stefan Ratering, Torsten Hain, Moritz Fritzenwanker, Alexander Goesmann, Jochen Blom, Trinad Chakraborty, Boyke Bunk, Cathrin Spröer, Jörg Overmann, Sylvia Schnell

“…To gain insights into the genetic bases of plant growth promotion and its lifestyle at the rhizosphere under salty conditions, we determined the complete genome sequence using two complementary sequencing platforms (Ilumina MiSeq and PacBio RSII). …”
Get full text

Effects of Single Nucleotide Polymorphism Marker Density on Haplotype Block Partition by Sun Ah Kim, Yun Joo Yoo

“…The location and distribution of haplotype blocks can be seen as a population property influenced by population genetic events such as selection, mutation, recombination and population structure. …”
Get full text

A 150 kDa Protein Derived from Bull Seminal Plasma Extended the Survival Time of Kacang Goat Sperm Stored at 5°C by Suherni Susilowati, Imam Mustofa, Wurlina Wurlina, Indah Norma Triana, Suzanita Utama, Budi Utomo

“…Artificial insemination has proven to be an effective method for increasing population size and genetic quality of Kacang goats. However, innovation is required to maintain the quality of Kacang goat semen in storage. …”
Get full text