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9801
A Group-Based Signal Timing Optimization Model Considering Safety for Signalized Intersections with Mixed Traffic Flows
Published 2019-01-01“…Then, the multiobjective optimization issue was formulated as a nonlinear program and solved by a Nondominated Sorting Genetic Algorithm. A numerical study was performed to demonstrate the applicability and performance of the proposed model. …”
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9802
Mycotoxic effects of entomopathogenic fungi of fall armyworm (Spodoptera frugiperda J.E. Smith) on poultry feed safety
Published 2024-02-01“…Sequenced data was analyzed and processed using Molecular Evolutionary Genetic Analysis 6.0 software. The results showed relative diversity of fall armyworm larvae with 11 species isolated belonging to Aspergillus, Penicillium, Fusarium, Trichoderma, Bipolaris and Irpex genus. …”
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9803
PARP Inhibitors in the Treatment of Ovarian Cancer
Published 2025-02-01“…Summary PARP inhibitors represent a significant advancement in ovarian cancer treatment, offering improved survival outcomes for patients with specific genetic profiles. Their integration into standard care protocols underscores their importance and efficacy, providing valuable therapeutic options in the fight against ovarian cancer. …”
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9804
Perioperative Management of a Patient with Hereditary Angioedema and Intestinal Obstruction Secondary to an Ileal Tumor: A Case Report
Published 2025-01-01“…Hereditary angioedema (HAE) is a rare genetic disorder resulting from deficiency or dysfunction of the C1-esterase inhibitor (C1-INH, C1-inhibitor) protein. …”
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9805
Human Umbilical Cord Blood-Derived Serum for Culturing the Supportive Feeder Cells of Human Pluripotent Stem Cell Lines
Published 2016-01-01“…Although human pluripotent stem cells (hPSCs) can proliferate robustly on the feeder-free culture system, genetic instability of hPSCs has been reported in such environment. …”
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9806
Fluoride-induced testicular and ovarian toxicity: evidence from animal studies
Published 2025-01-01“…In both males and females, F exerts its adverse effects by triggering apoptosis, autophagy, inflammation, mitochondrial dysfunction, reduction in ATP synthesis, and modulation of important genes involved in steroidogenesis. Furthermore, genetic susceptibility and individual variations in F metabolism may contribute to different responses to fluoride exposure.…”
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9807
Dias-Logan syndrome with a p.Leu360Profs*212 heterozygous pathogenic variant of in a Chinese patient: A case report
Published 2025-01-01“…Therefore, our case report enriches the existing literature on the clinical spectrum and genotype–phenotype correlations of BCL11A -related syndrome and provides some helpful information for diagnosis, management, and genetic counseling.…”
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9808
The Anthropocene and the biodiversity crisis: an eco-evolutionary perspective
Published 2025-01-01“…This crisis does not only affect the ecological dynamics of biodiversity, but also its evolutionary dynamics, including genetic diversity, an aspect that is generally neglected. …”
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9809
Improved production strain maintenance technique for Burkholderia mallei 5584 (Master seed) used for glander diagnostic agent production
Published 2024-03-01“…The previous strain maintenance technique involved its storage in its native state, which facilitated accumulation of genetic mutations and, ultimately modification of bacterial cell properties. …”
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9810
An IS element-driven antisense RNA attenuates the expression of serotype 2 fimbriae and the cytotoxicity of Bordetella pertussis
Published 2025-12-01“…Insertion sequences (IS) represent mobile genetic elements that have been shown to be associated with bacterial evolution and adaptation due to their effects on genome plasticity. …”
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9811
Eight Years of Norovirus Surveillance in Urban Wastewater: Insights from Next-Generation
Published 2025-01-01“…In this study, wastewater-based epidemiology (WBE) was used to monitor the circulation and genetic diversity of HNoVs in Rome over an eight-year period (2017–2024). …”
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9812
Glioblastoma with Both Oligodendroglioma and Primitive Neuroectodermal Tumor-Like Components in a Case with 9-Year Survival
Published 2018-01-01“…Young age, aggressive surgical resection, and pathologic and genetic features may have contributed to the long-term survival of the patient.…”
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9813
High Efficiency Direct Shoot Organogenesis from Leaf Segments of Aerva lanata (L.) Juss. Ex Schult by Using Thidiazuron
Published 2014-01-01“…Furthermore, this protocol may be used for a large scale production of its medicinally active compounds and genetic transformations for further improvement.…”
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9814
Targeted Regulation Of Cgrp Gene Expression
Published 2001-01-01“…This observation supports the importance of a finely tuned balance of calcium in the trigeminal neuron, which is intriguing in light of genetic evidence for calcium channel mutations in a rare form of inherited migraine. …”
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9815
Drought Tolerance in Modern and Wild Wheat
Published 2013-01-01“…Drought tolerance is crucial to stabilize and increase food production since domestication has limited the genetic diversity of crops including wild wheat, leading to cultivated species, adapted to artificial environments, and lost tolerance to drought stress. …”
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9816
Fate and long-lasting therapeutic effects of mesenchymal stromal/stem-like cells: mechanistic insights
Published 2025-02-01“…Recent studies have provided evidence that the uptake of ABs with a distinct genetic component can induce changes in gene expression through the process of epigenetic remodeling. …”
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9817
Translational regulation of PKD1 by evolutionarily conserved upstream open reading frames
Published 2025-12-01“…Mutations in PKD1 coding sequence and abnormal PKD1 expression levels contribute to the development of autosomal-dominant polycystic kidney disease, the most common genetic disorder. Regulation of PKD1 expression by factors located in the promoter and 3´ UTR have been extensively studied. …”
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9818
Influence of particle size on NIR spectroscopic characterization of sorghum biomass for the biofuel industry
Published 2025-01-01“…Grown under field conditions, a total of 113 types of genetically diverse sorghum accessions were dried, ground, and sieved (<250, 250–600, 600–850, and > 850 µm particle size) for developing partial least square regression (PLSR) prediction models for moisture, ash, extractive, glucan, xylan, acid-soluble lignin (ASL), acid-insoluble lignin (AIL), and total lignin (ASL + AIL). …”
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9819
Genomic, Evolutionary, and Pathogenic Characterization of a New <i>Polerovirus</i> in Traditional Chinese Medicine <i>Viola philippica</i>
Published 2025-01-01“…Two potential recombination events were identified within ORF2, ORF3a, and ORF3, providing insights into the genetic diversity and evolution history of this novel polerovirus. …”
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9820
Evidence that a STAT3 Mutation Causing Hyper IgE Syndrome Leads to Repression of Transcriptional Activity
Published 2019-01-01“…Th17 cell phenotyping revealed low levels of IL-17 expressing cells (0.3% of total CD4 T Cells numbers). Genetic analysis identified a missense mutation, N567D, in a conserved region of the linker domain of STAT3. …”
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