The Possible Crystallization Process in the Origin of Bacteria, Archaea, Viruses, and Mobile Elements by Akari Yoshimura, Masayuki Seki

“…The emergence process can be considered analogous to crystallization, where genetic and biochemical systems stabilize as organisms evolve from their common ancestor, the LUCA, which was a non-free-living pool of single operon type genomes including double-stranded (ds) DNA at an ancient submarine alkaline vent. …”
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Research on Non-Probabilistic Reliability Partitioning Methods for Large Workspace Robots by Jianping Sun, Weian Yang, Xin Meng, Jun Peng, Zhaoping Tang

“…The method considers the differences in non-probabilistic reliability of robot end positions in different workspace ranges and uses KLFCM clustering combined with a genetic algorithm to perform a two-stage hierarchical partitioning optimization. …”
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Autoimmune and Neoplastic Thyroid Diseases Associated with Hepatitis C Chronic Infection by Poupak Fallahi, Silvia Martina Ferrari, Ugo Politti, Dilia Giuggioli, Clodoveo Ferri, Alessandro Antonelli

“…These cytokines might induce a further CXCL10 secretion by thyrocytes, thus perpetuating the immune cascade, which may lead to the appearance of autoimmune thyroid disorders in genetically predisposed subjects. A careful monitoring of thyroid function, particularly where nodules occur, is recommended in HCV patients.…”
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DAB2IP Downregulation Enhances the Proliferation and Metastasis of Human Gastric Cancer Cells by Derepressing the ERK1/2 Pathway by Liang Sun, Yizhou Yao, Ting Lu, Zengfu Shang, Shenghua Zhan, Weiqiang Shi, Guofeng Pan, Xinguo Zhu, Songbing He

“…Potential roles of DAB2IP in regulating gastric cancer cell growth and metastasis were examined by genetic manipulation in vitro. The molecular signaling was determined to understand the mechanisms of observed DAB2IP effects. …”
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Fluoroquinolone-specific resistance trajectories in E. coli and their dependence on the SOS-response by Lisa Teichmann, Sam Luitwieler, Johan Bengtsson-Palme, Benno ter Kuile

“…Whole genome analysis indicated distinct genetic changes associated with each fluoroquinolone, highlighting potential different pathways and mechanisms involved in resistance. …”
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Investigating causal relationship among inflammatory cytokines and oropharyngeal cancer: Mendelian randomization by Sibo Xu, Yiguo Li, Wei Chen, Ke Wang

“…Methods This study investigated genetic variants that have been associated with oral and oropharyngeal cancer using data from a large GWAS. …”
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Residential Building Duration Prediction Based on Mean Clustering and Neural Network by Fanrong Ji, Yunquan Nan, Aifang Wei, Peiyan Fan, Zhaoyuan Luo, Xiaoqing Song

“…The duration of a residential building project will directly influence its successful implementation; hence, it is essential to estimate a reasonable timeframe. In this study, a genetic algorithm (GA) was employed to optimize and refine the weights and thresholds of a back propagation (BP) neural network, thereby creating a GA-BP neural network model. …”
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Rimegepant for the treatment of migraine by Amnon A. Berger, Ariel Winnick, Austin H. Carroll, Alexandra Welschmeyer, Nathan Li, Marc Colon, Antonella Paladini, Giovanni F. Ramírez, Jamal Hasoon, Elyse M. Cornett, Jaehong Song, Giustino Varrassi, Adam M. Kaye, Alan D. Kaye, Latha Ganti

“…The pathophysiology is an intricate interplay of genetic factors and environmental influence and is still being elucidated in ongoing studies. …”
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Genomic and phylogenetic analysis of a NDM-1 producing ST152 Klebsiella pneumoniae isolated from a bloodstream infection in China by Renchi Fang, Lingfang Di, Xuebin Tian, Yongfeng Bai

“…Our findings provide insights into the current status of resistance in new lineages within the region and enhance comprehension of K. pneumoniae carbapenem resistance transmission from a genetic structure perspective.…”
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Mendelian randomization analysis does not support a causal influence between lipoprotein(A) and immune-mediated inflammatory diseases by Yun Ti, Dan Xu, Xiaoning Qin, Yang Hu, Yuru Xu, Qingzhao Zhao, Peili Bu, Jingyuan Li

“…We didn’t observe a causal association between Lp(a) and the risk of IMIDs in univariable and multivariable MR analysis, challenging previous observational studies. However, genetically predicted lipid traits HDL-C was associated with increased risk of Type 1 diabetes (T1D). …”
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Recapitulation of Candidate Systemic Lupus Erythematosus-Associated Variants in Koreans by Ki-Sung Kwon, Hye-Young Cho, Yeun-Jun Chung

“…Although the etiology of SLE remains unclear, it is widely accepted that genetic factors could be involved in its pathogenesis. …”
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Structural Weight and Stiffness Optimization of a Midibus Using the Reinforcement and Response Surface Optimization (RSO) Method in Static Condition by Hailemichael Solomon Addisu, Ermias Gebrekidan Koricho

“…Response surface optimization with the multiobjective genetic algorithm (MOGA) method in ANSYS DesignXplorer was performed on the reinforced structure to maximize the bending and torsional stiffness with reduced weight. …”
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Chlorogenic Acids Inhibit Adipogenesis: Implications of Wnt/β-Catenin Signaling Pathway by Mengting Liu, Jian Qin, Jing Cong, Yubin Yang

“…In our previous in vitro study, we found that chlorogenic acid (CGA) inhibited adipocyte differentiation and triglyceride (TG) accumulation, but the underlying mechanism is still unclear. Accumulative genetic evidence supports that canonical Wnt signaling is a key modulator on adipogenesis. …”
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Pathogenic Process-Associated Transcriptome Analysis of Stemphylium lycopersici from Tomato by Dezhen Zhang, Wenjuan Chi, Cuicui Wang, Huijie Dai, Jintang Li, Chunlei Li, Fajun Li

“…In this study, a comparative transcriptomic analysis was performed and more genetic information on the pathogenicity determinants of S. lycopersici during the infection process in tomato were obtained. …”
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Predicting and synthesizing terahertz spoof surface plasmon polariton devices with a convolutional neural network model by Vahid Najafy, Bijan Abbasi-Arand, Maryam Hesari-Shermeh

“…Three examples are provided for inversely designing several sensor devices and absorbers in the terahertz band using the proposed CNN and the genetic optimization algorithm.…”
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Fifty years after the discovery of the association of HLA B27 with ankylosing spondylitis by Joachim Sieper, Juergen Braun

“…HLA B27 explains less than 30% of the total genetic load. About 60%–90% of axSpA patients worldwide carry HLA B27. …”
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Insights into the origin, hybridisation and adaptation of Candida metapsilosis hybrid pathogens. by Valentina Del Olmo, Álvaro Redondo-Río, Alicia Benavente García, Savitree Limtong, Ester Saus, Toni Gabaldón

“…Hybridisation is a source of genetic diversity, can drive adaptation to new niches and has been found to be a frequent event in lineages harbouring pathogenic fungi. …”
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METTL16 is Required for Meiotic Sex Chromosome Inactivation and DSB Formation and Recombination during Male Meiosis by Lisha Yin, Nan Jiang, Wenjing Xiong, Shiyu Yang, Jin Zhang, Mengneng Xiong, Kuan Liu, Yuting Zhang, Xinxin Xiong, Yiqian Gui, Huihui Gao, Tao Li, Yi Li, Xiaoli Wang, Youzhi Zhang, Fengli Wang, Shuiqiao Yuan

“…Abstract Meiosis in males is a critical process that ensures complete spermatogenesis and genetic diversity. However, the key regulators involved in this process and the underlying molecular mechanisms remain unclear. …”
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Assessment of energy management and power quality improvement of hydrogen based microgrid system through novel PSO-MWWO technique by Hafiz Ghulam Murtza Qamar, Xiaoqiang Guo, Ehab Seif Ghith, Mehdi Tlija, Abubakar Siddique

“…The achieved results and numerical analysis affirm the superiority of the proposed technique compared to other traditional methods like mixed integer linear programming (MILP), HOMER, Variable mesh optimization (VMO), and Cataclysmic genetic algorithm in optimizing component sizing, renewable production, hydrogen production, reliability, cost effective, and overall efficacy. …”
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Mathematical Modelling of Acetaminophen Release in HPC/PAAm Hydrogel: Synthesis and Application by Abigail M. Díaz-Guerrero, Claudia A. Castillo-Miranda, Carlos F. Castro-Guerrero, Hernán Peraza-Vázquez, Ana B. Morales-Cepeda, Adrián F. Peña-Delgado

“…In order to describe the release of acetaminophen in HPC/PAAm gel, a genetic programming algorithm was used to accomplish Multigene Symbolic Regression (MSR). …”
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