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9501
Cytoskeletal Vimentin Directs Cell‐Cell Transmission of Hepatitis C Virus
Published 2025-01-01“…Here, we demonstrated that vimentin, a host intermediate filaments protein, is dispensable for HCV infection in cell models but essential for simulated in vivo infection in differentiated hepatocytes. Genetic removal of vimentin markedly and specifically disrupts HCV cell–cell transmission without influencing cell‐free infection. …”
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9502
Evolutionary Computation with Spatial Receding Horizon Control to Minimize Network Coding Resources
Published 2014-01-01“…The minimization of network coding resources, such as coding nodes and links, is a challenging task, not only because it is a NP-hard problem, but also because the problem scale is huge; for example, networks in real world may have thousands or even millions of nodes and links. Genetic algorithms (GAs) have a good potential of resolving NP-hard problems like the network coding problem (NCP), but as a population-based algorithm, serious scalability and applicability problems are often confronted when GAs are applied to large- or huge-scale systems. …”
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9503
Selective Herbicides for Cultivation of Eucalyptus urograndis Clones
Published 2015-01-01“…Five herbicides, flumioxazin, imazamox, imazapic, oxyfluorfen, and sulfometuron methyl, were evaluated for selective weed control in the establishment of genetically modified frost tolerant Eucalyptus urograndis clones. …”
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9504
Atherosclerosis and Rheumatoid Arthritis: More Than a Simple Association
Published 2012-01-01“…On the other hand, also the increase of oxidative processes, frequently observed in RA, induces atherosclerosis. Interestingly, some genetic polymorphisms associated with RA occurrence enhance atherosclerosis, however, other polymorphisms associated with RA susceptibility do not increase CVD risk. …”
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9505
Challenges in Emerging Vaccines and Future Promising Candidates against SARS-CoV-2 Variants
Published 2024-01-01“…Therefore, understanding the amount and characteristics of coronavirus genetic diversity in historical and contemporary strains can help researchers get an edge over upcoming variants.…”
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9506
Understanding the complex function of gut microbiota: its impact on the pathogenesis of obesity and beyond: a comprehensive review
Published 2024-12-01“…Abstract Obesity is a multifactorial condition influenced by genetic, environmental, and microbiome-related factors. …”
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9507
Neurosurgical aspects of marble bone disease: treatment modalities and outcome
Published 2025-02-01“…Osteopetrosis has 3 types of genetic inheritance either malignant autosomal recessive (ARO) which occur in childhood, intermediate ARO which occur in adolescence, and benign autosomal dominant osteopetrosis which occur in adults. …”
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9508
Chemical signatures of social information in Barbary macaques
Published 2025-01-01“…In particular, we related socially relevant attributes (identity, genetic relatedness, rank, sex, age, group membership) to chemical profiles of body odor. …”
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9509
DNA metabarcoding technology for the identification of the fecal microbiome in patients with chronic stress
Published 2024-06-01“…Next Generation Illumina genetic sequencing targeting the 16S rDNA gene was then performed, followed by bioinformatic analysis using QUIME II software. …”
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9510
Toll-like receptors in atopic dermatitis: pathogenesis and therapeutic implications
Published 2025-02-01“…The dysregulation of proinflammatory and immunomodulatory effects of TLRs can be attributed to their ligand structures, receptor heterodimerization, the relative frequency of each TLR, interactions with other receptors/signalling pathways, cytokine milieu, and genetic polymorphisms. Current AD treatments like vitamin-D analogs, tacrolimus, and cyclosporine partially work through TLR modulation. …”
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9511
Female urethral diverticular carcinoma: a case report and review of the literature
Published 2025-01-01“…For patients with distant metastasis, a combination of surgery, chemotherapy, and radiotherapy may be considered.Genetic testing and targeted immunotherapy offer new approaches for future treatment.…”
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9512
Evaluation of acitretin side effects on Iraqi psoriatic patients
Published 2010-12-01“…There is other important factors should be consider before evaluation the physiological changes may be caused by acitretin like smoking , alcohol intake , obesity and genetic association between psoriasis and other physiological change. …”
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9513
Pathogenic PDE12 variants impair mitochondrial RNA processing causing neonatal mitochondrial disease
Published 2024-11-01“…Within this group, an increasing number of families have been identified, where Mendelian genetic disorders implicate defective mitochondrial RNA biology. …”
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9514
Short-Term Prediction of Traffic State for a Rural Road Applying Ensemble Learning Process
Published 2021-01-01“…As there are many influential features on traffic state, the genetic algorithm (GA) has been used to identify 25 of 32 features, which are the most influential on models’ fitness. …”
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9515
A multi-objective mathematical model for optimization design of humanitarian logistics network using meta-heuristic algorithm: a model to enhance actors’ coordination
Published 2024-06-01“…The proposed model has been solved using two metaheuristic algorithms named multi-objective genetic algorithm and multi-objective particle swarm optimization.Findings: The implementation of this study will lead to a reduction in the costs of locating, routing and reconstruction in the humanitarian supply chain, as well as reducing the time of providing aid to the affected people and increasing their satisfaction. …”
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9516
Molecular pathways in reproductive cancers: a focus on prostate and ovarian cancer
Published 2025-02-01“…This review aims to provide an overview of the molecular pathways implicated in prostate and ovarian cancers, highlighting key genetic alterations, signaling cascades, and epigenetic modifications. …”
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9517
Expression of cell-wall related genes is highly variable and correlates with sepal morphology
Published 2023-09-01“…We produced a dataset composed of morphological parameters and genome-wide transcriptome obtained from 27 individual sepals from wild-type plants with nearly identical genetic backgrounds, environment, and developmental stage. …”
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9518
Data analysis of high-throughput sequencing and microarray to identify key signatures of microribonucleic acids in glioblastoma
Published 2021-09-01“…This research was devoted to study of mRNA and miRNA expression patterns in glioglastomas using The Cancer Genome Atlas (TCGA) data, to search for genetic determinants that determine the prognosis of patient survival and to create of interaction networks for glioblastomas.Materials and methods. …”
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9519
Case Study of Somaclonal Variation in Resistance Genes Mlo and Pme3 in Flaxseed (Linum usitatissimum L.) Induced by Nanoparticles
Published 2017-01-01“…Gene region specific primers were developed for resistance genes such as Mlo and Pme3 to define the genetic variability in tissue culture of L. usitatissimum. …”
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9520
How energy determines spatial localisation and copy number of molecules in neurons
Published 2025-02-01“…Abstract In neurons, the quantities of mRNAs and proteins are traditionally assumed to be determined by functional, electrical or genetic factors. Yet, there may also be global, currently unknown computational rules that are valid across different molecular species inside a cell. …”
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