The Bipolar Depression Electrical Treatment Trial (BETTER): Design, Rationale, and Objectives of a Randomized, Sham-Controlled Trial and Data from the Pilot Study Phase by Bernardo de Sampaio Pereira Junior, Gabriel Tortella, Beny Lafer, Paula Nunes, Isabela Martins Benseñor, Paulo Andrade Lotufo, Rodrigo Machado-Vieira, André R. Brunoni

“…Biological markers such as blood neurotrophins and interleukins, genetic polymorphisms, heart rate variability, and motor cortical excitability will be assessed. …”
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Structural engineering of stabilized, expanded epitope nanoparticle vaccines for HPV by Michaela Helble, Michaela Helble, Xizhou Zhu, Pratik S. Bhojnagarwala, Kevin Liaw, Yangcheng Gao, Amber Kim, Kelly Bayruns, Madison E. McCanna, Joyce Park, Kylie M. Konrath, Kylie M. Konrath, Sam Garfinkle, Sam Garfinkle, Taylor Brysgel, David B. Weiner, David B. Weiner, Daniel W. Kulp, Daniel W. Kulp

“…We further tested nanoparticles in a genetically diverse, more translationally relevant CD-1 mouse model and demonstrated that both E6 and E7 nanoparticle designs drove a CD8+ biased T-cell response. …”
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The Role of the Pathoanatomical Diagnosis «Chronic Gastritis» in the System of Personified Cancer Prevention by A. V. Kononov

“…Biopsy diagnosis of chronic gastritis combined with the evaluation of gene structure (genetic polymorphism) and epigenomic mechanisms (microRNA) allows the risk of gastric cancer to be ranked in a particular patient even with early precancerous changes in the gastric mucosa. …”
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Dysplasia in Inflammatory Bowel Diseases: Definition and Clinical Impact by Karel Geboes, Paul Rutgeerts

“…Additional techniques to search for genetic defects associated with carcinogenesis can help to support the diagnosis. …”
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Segment Any Leaf 3D: A Zero-Shot 3D Leaf Instance Segmentation Method Based on Multi-View Images by Yunlong Wang, Zhiyong Zhang

“…Exploring the relationships between plant phenotypes and genetic information requires advanced phenotypic analysis techniques for precise characterization. …”
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Inference Attacks on Genomic Data Based on Probabilistic Graphical Models by Zaobo He, Junxiu Zhou

“…., leakage unwittingly, or after their releasing intentionally to genetic service platforms), kin-genomic data privacy is threatened. …”
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Standardization of Micropropagation for Four Hybrids of <i>Coffea arabica</i> Through Direct Somatic Embryogenesis by Marileydi Zuta-Puscan, Jegnes Benjamín Meléndez-Mori, Eyner Huaman-Huaman, Yoiner Kalin Lapiz-Culqui, Reyna Stefani Mego-Pérez, Manuel Oliva-Cruz

“…Direct somatic embryogenesis represents a fundamental tool for obtaining genetically homogeneous clones; however, its commercial scaling faces critical challenges at various stages of the process. …”
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Maximizing efficiency and performance of water distribution systems through the implementation of optimization algorithms: A comprehensive analysis of valve and chlorine booster pl... by Mohamadreza Najarzadegan, Mehrtash Eskandaripour

“…By employing advanced optimization algorithms, specifically the Genetic Algorithm (GA) and Slime Mould Algorithm (SMA), the research identifies optimal configurations across two benchmark networks, Jowitt and Xu and GoYang. …”
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Characterization of covalent inhibitors that disrupt the interaction between the tandem SH2 domains of SYK and FCER1G phospho-ITAM. by Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman

“…RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative targets to be modulated for Alzheimer's disease (AD) therapy. …”
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Endothelial STAT3 Modulates Protective Mechanisms in a Mouse Ischemia-Reperfusion Model of Acute Kidney Injury by Shataakshi Dube, Tejasvi Matam, Jessica Yen, Henry E. Mang, Pierre C. Dagher, Takashi Hato, Timothy A. Sutton

“…Consequently, we used a mouse with a genetic deletion of Stat3 restricted to the endothelium to examine the role of STAT3 signaling in the pathophysiology of ischemic AKI. …”
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The Construction of Regulatory Network for Insulin-Mediated Genes by Integrating Methods Based on Transcription Factor Binding Motifs and Gene Expression Variations by Hyeim Jung, Seonggyun Han, Sangsoo Kim

“…Type 2 diabetes mellitus is a complex metabolic disorder associated with multiple genetic, developmental and environmental factors. …”
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Psoriasis: Unraveling Disease Mechanisms and Advancing Pharmacological and Nanotechnological Treatments by Miao M, Yan J, Sun Y, Liu J, Guo S

“…The identification of age, gender, and genetic factors contributing to these complex conditions has been pivotal in developing novel pharmacological and technological treatments. …”
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An Efficient Tourism Path Approach Based on Improved Ant Colony Optimization in Hilly Areas by Mohamed A. Damos, Wenbo Xu, Jun Zhu, Ali Ahmed, Abdolraheem Khader

“…The limitations of the traditional ACO and the Genetic Algorithm (GA) are addressed by improving pheromone updating techniques and implementing new initialization parameters. …”
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Insights on the utilisation of tissue culture to aid new breeding techniques for cowpea (Vigna unguiculata L.) improvement by Malizukiswe Vincent Vacu, Promise Sifiso Nzama, Muyiwa Seyi Adegbaju

“…Conventional plant breeding techniques have produced new varieties of cowpeas, yet the limited genetic diversity within cultivated cowpeas poses challenges for future conventional breeding efforts. …”
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Gray matter volume and asymmetry in Broca's and Wernicke's area homologs in chimpanzees (Pan troglodytes) using a probabilistic region of interest approach by William D Hopkins, Muhammad A Spocter, Michele M Mulholland, Chet C Sherwood

“…Lastly, using quantitative genetic analyses, we found significant heritability in the average gray matter volume for BA44 and BA45 but not BA22. …”
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The Critical Role of Bach2 in Shaping the Balance between CD4+ T Cell Subsets in Immune-Mediated Diseases by Lingyi Yang, Shuli Chen, Qiuyu Zhao, Ying Sun, Hong Nie

“…Bach2 is also critical for the formation and function of CD4+ T cell lineages (Th1, Th2, Th9, Th17, T follicular helper (Tfh), and regulatory T (Treg) cells). Genetic variations within Bach2 locus are associated with numerous immune-mediated diseases including multiple sclerosis (MS), rheumatoid arthritis (RA), chronic pancreatitis (CP), type 2 chronic airway inflammation, inflammatory bowel disease (IBD), and type 1 diabetes. …”
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Nutritional and Phytochemical Variation of Marula (Sclerocarya birrea) (Subspecies caffra and birrea) Fruit among Nine International Provenances Tested in Malawi by Mussa Kamanula, Chimuleke Yagontha Munthali, John Finias Kamanula

“…Variations observed in nutritional and phytochemical composition could be attributed to genetic make-up and origin of the genotypes, since all genotypes were planted in the same environment. …”
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The Association between Adiponectin Single Nucleotide Polymorphisms and Side Effects of Isotretinoin in Acne Patients by Munir Garba, Omar F. Khabour, Karem H. Alzoubi, Ahmed Abu-Siniyeh, Firas Al-Qarqaz

“…In this study, the effect of genetic polymorphisms, rs2241766 and rs1501299, of the adiponectin gene was investigated in relation to the side effects of isotretinoin-treated young adult acne patients (n = 230). …”
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Systematic analysis of the pharmacogenomics landscape towards clinical implementation of precision therapeutics in Greece by George P. Patrinos, Kariofyllis Karamperis, Margarita-Ioanna Koufaki, Maria Skokou, Zoe Kordou, Eirini Sparaki, Margarita Skaraki, Christina Mitropoulou

“…Abstract Pharmacogenomics (PGx) aims to delineate a patient’s genetic profile with differences in drug efficacy and/or toxicity, particularly focusing on genes encoding for drug-metabolizing enzymes and transporters. …”
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Clinico-epidemiology and aetiopathogenesis of gallstone disease in the South Asian region: a scoping review protocol by Harshi Weerakoon, Ishari Vithanage, Oshadhi Alahakoon, Kosala Weerakoon

“…Introduction Pathogenesis of gallstones (GS) is multifactorial and is influenced by numerous environmental and genetic risk factors. As a result, clinico-epidemiology and aetiopathogenesis of GS vary in different populations. …”
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