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9481
An Evolutionary Video Assignment Optimization Technique for VOD System in Heterogeneous Environment
Published 2010-01-01“…In order to find a near-optimal solution for such a complex video assignment problem, an evolutionary approach based on genetic algorithm (GA) is proposed. From the results, it is shown that the system performance can be significantly enhanced by efficiently coupling the various techniques.…”
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9482
Application of Bat Algorithm for Transport Network Design Problem
Published 2019-01-01“…Soft computing techniques like Genetic Algorithms, Ant Colony Optimization, and many other biologically inspired techniques prove to give good results for bilevel problems. …”
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9483
Plasmid Gene Therapy for Monogenic Disorders: Challenges and Perspectives
Published 2025-01-01“…In recent years, gene therapy has appeared as a promising approach for addressing genetic disorders. However, despite advancements in gene manipulation tools and delivery systems, several challenges remain unresolved, including inefficient delivery, lack of sustained expression, immunogenicity, toxicity, capacity limitations, genomic integration risks, and limited tissue specificity. …”
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9484
Hypertrophic Cardiomyopathy Mimicking Acute Anterior Myocardial Infarction Associated with Sudden Cardiac Death
Published 2012-01-01“…Hypertrophic cardiomyopathy is the most common genetic disease of the heart. We report a rare case of hypertrophic obstructive cardiomyopathy mimicking an acute anterior myocardial infarction associated with sudden cardiac death. …”
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9485
Case report: Basal cell carcinoma arising within the nevus sebaceous: report of 4 cases and literature review
Published 2025-01-01“…The etiology of NS may be linked to genetic mutations or ultraviolet exposure. Treatment options vary, with surgical resection likely being the most common method of eradication.…”
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9486
A Pediatric Case of Systemic Lupus Erythematosus Developed 10 Years after Cord Blood Transplantation for Juvenile Myelomonocytic Leukemia
Published 2012-01-01“…Bone marrow examination showed complete remission without monosomy 7. Genetic analysis of peripheral blood revealed mixed chimera with recipient cells consisting of <5% of T cells, 50–60% of B cells, 60–75% of NK cells, 70–80% of macrophages, and 50–60% of granulocytes. …”
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9487
Cryo-electron tomography pipeline for plasma membranes
Published 2025-01-01“…The pipeline allows for angstrom-scale structure determination with subtomogram averaging and employs a genetically encodable rapid chemically-induced electron microscopy visible tag for marking specific proteins within the complex cellular environment. …”
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9488
A Primer on the Role of TP53 Mutation and Targeted Therapy in Endometrial Cancer
Published 2025-01-01“…The occurrence and development of EC is closely associated with genetic mutations. TP53 mutation, in particular, can lead to the dysfunction of numerous regulatory factors and alteration of the tumor microenvironment (TME). …”
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9489
Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction
Published 2025-01-01“…Here, RNA sequencing identifies Forkhead Box1 (FoxO1) signaling as abnormal in male HFpEF hearts. Genetic suppression of FoxO1 alters the intercellular communication between cardiomyocytes and fibroblasts, alleviates abnormal diastolic relaxation, and reduces arrhythmias. …”
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9490
The treatment of irritable bowel syndrome from the modern views on the disease pathogenesis
Published 2013-03-01“…The data received in the recent years provide evidence about the fact that in the development of IBS the genetic factors, the inflammatory changes of the intestinal mucosa and the violation of the balance of the gut microflora play the important role. …”
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9491
Whole-genome sequence of bioactive streptomycete derived from mangrove forest in Malaysia, Streptomyces sp. MUSC 14
Published 2021-04-01“…This information serves as an important foundation for subsequent studies, particularly the purification and isolation of bioactive compounds by genetic manipulation techniques. …”
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9492
Effects of Calcium Ion, Calpains, and Calcium Channel Blockers on Retinitis Pigmentosa
Published 2011-01-01“…Recent advances in molecular genetic studies have revealed many of the causative genes of retinitis pigmentosa (RP). …”
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9493
A relação entre ciência e ideologia em tempos de hegemonia financeira: a biotecnociência e o mercado de promessas
Published 2019-01-01“…From the need to understand the systematic presence, in the most different media of scientific dissemination, of the figuration of the human being as being ontologically equal to other animals, mainly because of their molecular biological characteristics, such as genetic ones. This work seeks to put on the scene a critical theoretical approach about how the social construction of biotechnologies and the scientific discourses that underpin them are biased by subordination to the financial market, making in contemporary society the social relations between science and ideology are resignification. …”
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9494
Ketamine Therapy in Complex Cases: A Cautionary Tale of Exacerbated Personality Traits and the Crucial Role of Comprehensive Follow-Up and Psychosocial Interventions
Published 2024-01-01“…The report delves into the patient’s complex background, including psychosocial stressors, genetic predisposition to depression, and a history of personality traits that may have influenced her response to ketamine. …”
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9495
Costello Syndrome. A case report
Published 2014-06-01“…Early diagnosis allows early stimulation and intervention, active screening for tumor lesions, as well as provision of genetic counselling to patients.…”
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9496
When Ribonucleases Come into Play in Pathogens: A Survey of Gram-Positive Bacteria
Published 2012-01-01“…Implications on bacterial evolution through stabilization/transfer of genetic material (phage or plasmid DNA) as a result of ribonucleases' functions will be covered. …”
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9497
Floridians’ Perceptions of GMOs: GMOs and Florida Citrus
Published 2014-10-01“…This 4-page fact sheet is intended to help Extension faculty understand public perceptions regarding the use of genetic engineering to combat citrus greening. Extension faculty can use this understanding of public perceptions as they develop and deliver programming for clientele. …”
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9498
Nanosystems for modulation of immune responses in periodontal therapy: a mini-review
Published 2025-01-01“…The current understanding of the pathogenesis of periodontitis has unraveled the importance of the inflammatory and immune reactions to combat periodontitis whose etiology is an overlap of microbial, genetic, and environmental factors in a susceptible host. …”
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9499
Optimum Design of Load Capacity of Cycloidal Pin Wheel
Published 2022-08-01“…Matlab is used to call the genetic algorithm in its optimization toolbox for solution. …”
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9500
Engineering of ovarian tissue for ovarian dysfunctions: A review
Published 2024-01-01“…This review explores tissue engineering as a potential solution for reproductive health issues in women caused by genetic or acquired diseases, such as premature ovarian failure or oophorectomy. …”
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