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9421
Maltreatment-Associated Psychiatric Problems: An Example of Environmentally Triggered ESSENCE?
Published 2013-01-01“…Individual disorders associated with maltreatment are discussed as well as the overlap between these disorders and their shared environmental and genetic predisposing factors. Because of the complex and overlapping nature of MAPP, with symptoms emerging in early life, I argue that it should be considered an example of ESSENCE. …”
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9422
Lentiviral-Mediated shRNA Silencing of PDE4D Gene Inhibits Platelet-Derived Growth Factor-Induced Proliferation and Migration of Rat Aortic Smooth Muscle Cells
Published 2011-01-01“…Our results implicate that PDE4D has an important role in VSMC proliferation and migration which may explain its genetic susceptibility to ischemic stroke.…”
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9423
Florida Cow-Calf and Stocker Beef Safety and Quality Assurance Handbook: Quality Control Points
Published 2006-10-01“…It describes management approaches for five areas of quality concern: breeding and genetic selection, utilization of animal health products and practices, processing/cattle handling, nutrition, and culling management. …”
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9424
Brugada syndrome update
Published 2025-01-01“…Brugada syndrome (BrS), a genetic disorder affecting cardiac ion channels, predominantly manifests due to mutations that impair the function of the Nav1.5 sodium channel’s α-subunit. …”
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9425
Rubinstein-Taybi Syndrome: A Case Report
Published 2012-01-01“…Rubinstein-Taybi syndrome or Broad Thumb-Hallux syndrome is a genetic disorder characterized by facial dysmorphism, growth retardation, and mental deficiency. …”
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9426
The Role of Social Determinants of Health in Childhood Epilepsy
Published 2025-01-01“…Despite notable advancements in understanding the genetic and molecular underpinnings of pediatric epilepsies, there remains a relative lack of knowledge about the nature and impact of SDHs on these disorders. …”
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9427
Multiple Approaches to Investigate the Transport and Activity-Dependent Release of BDNF and Their Application in Neurogenetic Disorders
Published 2012-01-01“…Studies utilizing genetic and pharmacological manipulations in rodent models and neuronal cultures have revealed myriad roles of brain-derived neurotrophic factor (BDNF). …”
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9428
Circadian Rhythm Disturbances in Mood Disorders: Insights into the Role of the Suprachiasmatic Nucleus
Published 2017-01-01“…In turn, through synaptic and hormonal mechanisms, the SCN can drive and synchronize circadian rhythms in extra-SCN brain regions and peripheral tissues. Thus, genetic or environmental perturbations of SCN rhythms could disrupt brain regions more closely related to mood regulation and cause mood disturbances. …”
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9429
DYNAMIC ANALYSIS AND OPTIMIZATION OF IMPACT MECHANISM FOR IMPACTING AND BREAKING ROCK ROADEADER
Published 2017-01-01“…In order to improve the impact mechanism of the impacting and breaking rock roadheader dynamic characteristics under the cycle impact load,the first six natural frequency and mode shape as well as the displacement-frequency curves were obtained by using stress wave synthesis theory and finite element method in the paper,the modal and harmonic response of the mechanism were analyzed,the main deformation portion and main vibration direction and three axial weakest points of the mechanism were confirmed,structure size optimization of the rocker arm were adopted with multiple objective genetic algorithm,The maximum displacement response of the mechanism was reduced,and the dynamic characteristics of the mechanism were improved,which provides a method and basis for researching and improving the dynamic performance of the mechanism.…”
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9430
The first complete mitochondrial genome sequence of the common Baya weaverbird (Ploceus philippinus) from southern India
Published 2025-03-01“…The mitochondrial genome sequence would benefit future genetic studies in weaverbirds.…”
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9431
L’auteur dramatique plaidera coupable
Published 2013-02-01“…Four authors think this theme through and depict it: Cocteau, Aymé, Genet and Sartre. They choose a mode of expression that seems to be necessary to evoke it: the theater, which addresses easily that subject because its structure and its operation are similar to those of a court. …”
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9432
Infantile undifferentiated sarcomas: a diagnostic and therapeutic challenge – two case reports and literature review
Published 2025-02-01“…Background: Soft tissue undifferentiated sarcomas (STUS) are an ultra-rare and heterogenous group of mesenchymal neoplasms often lacking known genetic abnormalities with a marked vulnerability towards intensive therapy such as invasive surgery and high dose chemotherapy. …”
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9433
A Novel Antifragility Measure Based on Satisfaction and Its Application to Random and Biological Boolean Networks
Published 2019-01-01“…Our measure and results can be used in various applications of Boolean networks (BNs) including creating antifragile engineering systems, identifying the genetic mechanism of antifragile biological systems, and developing new treatment strategies for various diseases.…”
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9434
Research on Gear Modification Optimization Design of Dual Power Drive Gearbox
Published 2022-07-01“…Based on this,through genetic algorithm, the gear comprehensive modification optimization design combining tooth profile modification and helical modification is carried out, and the gear pair before and after modification is compared and analyzed. …”
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9435
Congenital Lipoid Adrenal Hyperplasia, as a Poorly Understood Cause of 46 XY Sexual Differentiation Disorder
Published 2024-01-01“…We present the case of a woman who, during the neonatal period, presented salt-losing adrenal insufficiency associated with 46 XY gonadal dysgenesis. The genetic study found a steroidogenic acute regulatory protein (StAR) mutation. …”
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9436
Optimal coalition structure generation strategy in multi-task concurrent edge computing environment
Published 2023-02-01“…A discrete recent past-position updating strategy based m-ary discrete particle swarm optimization (MDPSO-DRPPUS) algorithm was proposed for the problem of large search space and low efficiency when solving the optimal coalition structure.First, the coalition structure with index-based was coded.Then, the multi-objective optimization problem was transformed into an eigenvalue function of the coalition structure.Finally, the optimal coalition structure was searched by using the MDPSO-DRPPUS algorithm.Experiments show that compared with the m-ary discrete particle swarm optimization (MDPSO) algorithm and genetic algorithm (GA), the proposed algorithm dramatically reduces the average running time, and improves the efficiency and equilibrium of the coalition structure and task completion efficiency of edge nodes.…”
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9437
Chronic Granulomatous Disease Presenting as Aseptic Ascites in a 2-Year-Old Child
Published 2013-01-01“…Cultures were negative for infection throughout his course, and CGD was suspected after identification of granulomas on peritoneal biopsy. Genetic testing revealed a novel mutation in the CYBB gene underlying his condition. …”
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9438
The Structure of Bit-String Similarity Networks
Published 2025-01-01“…We study the structural properties of networks formed by random sets of bit strings—namely the ordered arrays of binary variables representing, for instance, genetic information or cultural profiles. Two bit strings are connected by a network link when they are sufficiently similar to each other, i.e., when their Hamming distance is below a certain threshold. …”
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9439
Research on the Rate of Penetration Prediction Method Based on Stacking Ensemble Learning
Published 2023-01-01“…This model integrates the K-nearest neighbor algorithm and support vector machine algorithm by stacking ensemble strategy and uses genetic algorithm to optimize model parameters, forming a new method of ROP prediction suitable for this oilfield. …”
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9440
Evolutionary Game Algorithm for Image Segmentation
Published 2017-01-01“…Experimental results show that the method proposed in this paper makes the detail of segmentation image syllabify and has better antijamming capability; the improved genetic algorithm which used searching optimal solution has faster convergence speed and better global search capability.…”
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