FHL1 as a prognostic biomarker and therapeutic target in acute promyelocytic leukaemia by Bo Luo, Wei Li, Jingyuan Zeng, Yingyu Mao, Shuang He, Nan Hu, Qulian Guo, Xiaoli Zheng

“…Most cases of leukemias are caused by environmental factors interacting with the cell’s genetic material, but treatment is still dominated by cell cycle drugs. …”
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Autonomous sortie scheduling for carrier aircraft fleet under towing mode by Zhilong Deng, Xuanbo Liu, Yuqi Dou, Xichao Su, Haixu Li, Lei Wang, Xinwei Wang

“…To efficiently solve the formulated HFSP, which is essentially a combinatorial problem with tightly coupled constraints, a chaos-initialized genetic algorithm is developed. The solution framework is validated by the simulation environment referring to the Fort-class carrier, exhibiting higher sortie efficiency when compared to existing strategies. …”
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Diversity, Distribution, and Evolution of Bioluminescent Fungi by Brian A. Perry, Dennis E. Desjardin, Cassius V. Stevani

“…Recent studies have elucidated the biochemical and genetic pathways of fungal bioluminescence and suggest the phenomenon originated a single time early in the evolution of the Agaricales. …”
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CRISPR/cas9 Allows for the Quick Improvement of Tomato Firmness Breeding by Qihong Yang, Liangyu Cai, Mila Wang, Guiyun Gan, Weiliu Li, Wenjia Li, Yaqin Jiang, Qi Yuan, Chunchun Qin, Chuying Yu, Yikui Wang

“…We generated single and double gene knockout mutants utilizing the tomato genetic transformation system. The fruit firmness of all knockout mutants exhibited a significant enhancement, with the most pronounced improvement observed in the double mutant. …”
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Rotavirus in Calves and Its Zoonotic Importance by Umer Seid Geletu, Munera Ahmednur Usmael, Fufa Dawo Bari

“…Reassortment is one of the important mechanisms for generating genetic diversity of rotaviruses and eventually for viral evolution. …”
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<i>Thermithiobacillus plumbiphilus</i> AAFK—Arsenic-Resistant Bacteria Isolated from Arsenopyrite Material by Artem Shaikin, Anton Zvonarev, Mikhail Vainshtein, Tatiana Abashina

“…Experiments on the arsenopyrite bioleaching showed that <i>T. plumbiphilus</i> AAFK can be used as an auxiliary bacterial culture capable of oxidizing reduced / intermediate sulfur compounds. The genetic basis of the <i>T. plumbiphilus</i> AAFK resistance to the arsenic compounds is discussed; the mechanisms are similar with the ones known for acidophilic thiobacilli. …”
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Association of Cytotoxic T Lymphocyte Antigen-4 Gene Polymorphisms with Psoriasis Vulgaris: A Case-Control Study in Turkish Population by Hatice Gül Dursun, Hüseyin Osman Yılmaz, Recep Dursun, Sevsen Kulaksızoğlu

“…No statistically significant associations were detected in any of the investigated genetic models for the −318C>T polymorphism. The genotype distributions of +49A>G and CT60A>G were associated with Pv development. …”
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Detection and Validation of A2 Milk Suitable for Consumers Having Milk Intolerance by ELISA Method by Mediha Esra Yayla

“…Casein proteins, which make up 80% of the total proteins in cow's milk, consist of mainly A1 and A2 genetic types which differ by a mutation that causes conversion from proline to histidine. …”
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A cross-tissue transcriptome-wide association study identified susceptibility genes for age-related macular degeneration by Hongfan Yang, Haofei Huang, Kunlin Pu

“…Abstract Age-related macular degeneration (AMD) is a complex multifactorial disease with a significant genetic component. Despite extensive research efforts, the underlying molecular mechanisms remain elusive, necessitating innovative approaches to identify specific genes involved in the pathogenesis of AMD and to elucidate their functional mechanisms. …”
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Cicer arietinum abscisic acid receptor PYL1 and glycine-rich RNA-binding, abscisic acid-inducible protein-like differential expression under induced draught conditions by Slishchuk Heorhii, Volkova Nataliia, Dilafruz Kholmurodova

“…These results highlight the importance of the abscisic acid receptor PYL1 in adaptation to drought stress and provide insight into the molecular response of chickpea to drought, laying the foundation for further genetic improvement of drought tolerance in this crop.…”
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A Car-Following Model Based on Safety Margin considering ADAS and Driving Experience by Yugang Wang, Nengchao Lyu

“…Other four parameters (SMDL, SMDH, α1, and α2) were calibrated using a classical genetic algorithm, and the effects of ADAS and driving experience in these four parameters were analyzed using T-test. …”
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Human Development X: Explanation of Macroevolution Top-Down Evolution Materializes Consciousness. The Origin of Metamorphosis by Tyge Dahl Hermansen, Søren Ventegodt, Joav Merrick

“…We propose the most important genetic and biochemical process that we think is behind the evolutionary shift as a complicated symbiosis of mechanisms leading to metamorphosis in all biological individuals, from bacteria to humans. …”
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Comparative Analysis of the Full-Length Genome Sequence of a Clinical Isolate of Human Parainfluenza Virus 4B by John A. Lednicky, Thomas B. Waltzek, Micah D. Halpern, Sara B. Hamilton

“…Here, we compare and contrast the genetic features of the three completely sequenced hPIV-4B genomes currently present in GenBank.…”
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Response of Sorghum to Cold Stress at Early Developmental Stage by Amandin Rutayisire, Geoffrey Lubadde, Alice Mukayiranga, Richard Edema

“…Native and adapted to the semiarid tropical regions of Africa, sorghum (Sorghum bicolor) is generally sensitive to cold temperatures, especially during the early developmental stages. However, there is genetic variability within the existing germplasm in terms of tolerance to low temperatures. …”
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Analysis of Fractional Order Mathematical Model of Hematopoietic Stem Cell Gene-Based Therapy by Mohammad Imam Utoyo, Windarto, Aminatus Sa’adah

“…This therapy protects target cells from infections or specifying technic and immune responses to face virus by using genetically modified HSCs. A mathematical model approach could be used to predict the dynamics of HSC gene-based therapy of viral infections. …”
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A Decision-Making Model for Autonomous Vehicles at Urban Intersections Based on Conflict Resolution by Zi-jia Wang, Xue-mei Chen, Pin Wang, Meng-xi Li, Yang-jia-xin Ou, Han Zhang

“…After that, a nondominated sorting genetic algorithm (NSGA-II) and deep deterministic policy gradient (DDPG) are employed to select the optimal motions in comparison with each other. …”
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Occurrence of antibiotics and antibiotic resistance genes at various stages of different aquaculture modes surrounding Tai Lake, China by Congcong Wu, Congcong Wu, Haitao Ye, Mingzhu Xu, Xuan Zhao, Xuejie Zhao, Lina Li, Mingzhi Li, Yanfei Wei, Yuru Li, Baolan Hu, Baolan Hu

“…However, the occurrence of antibiotics and ARGs under different modes and stages of aquaculture has rarely been systematically studied.MethodsThis paper uses qPCR, LC-MS, and High-Throughput sequencing across different culture modes and stages to investigate antibiotics, resistance genes, and microbial communities in the water bodies, and analyze contamination differences between these modes.ResultsThe quinolone and chloramphenicol were the main antibiotics, and the highest absolute abundance genes were quinolone resistance genes (qnrB) and quinolone resistance genes (sul1), with the mobile genetic element (MGE) intI1, both of which exhibited a gradual seasonal increase. …”
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An Estimation Model on Electricity Consumption of New Metro Stations by Zhao Yu, Yun Bai, Qian Fu, Yao Chen, Baohua Mao

“…., passenger volume, air temperature and relative humidity). A genetic algorithm with five-fold cross-validation is used to optimize the hyper-parameters of the SVR model in order to improve its accuracy in estimating the electricity consumption of a metro station (ECMS). …”
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Epidemiology of sickle cell disease in tribal population of Southern Rajasthan, India by Anil Purohit, Ramesh K. Huda, Suman S. Mohanty, Bontha V. Babu

“…Abstract Background & objectives Sickle Cell Disease (SCD), a genetic condition, carries significant public health implications due to its impact on mortality, morbidity and quality of life. …”
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The Borrachudos Granitic Suite: Paleo- to Mesoproterozoic A-type Magmatism in the Southeastern São Francisco Craton (SE Brazil) by IVO ANTONIO DUSSIN, MARIO LUIZ S.C. CHAVES, TANIA MARA DUSSIN, PHILLIPPE ROSSI, JACQUES CHARVET

“…To investigate the nature of this magmatism, mineralogical, geochemical, Nd-Sr isotopic studies in the BGS and genetically related metarhyolites inside the fold belt were carried out. …”
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