Cannabinoid Receptor 1 Gene Polymorphisms and Nonalcoholic Fatty Liver Disease in Women with Polycystic Ovary Syndrome and in Healthy Controls by Justyna Kuliczkowska Plaksej, Lukasz Laczmanski, Andrzej Milewicz, A. Lenarcik-Kabza, Anna Trzmiel-Bira, Urszula Zaleska-Dorobisz, Felicja Lwow, Lidia Hirnle

“…To determine the role of genetic variants of CNR1 in the etiopathology of NAFLD in women with PCOS. …”
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Post-mortem and histological lesions in the European minks (Mustela lutreola) induced by spontaneous infection with coronavirus SARS-CoV-2 by I. A. Subbotina, I. N. Gromov

“…Profound and detailed studies of the virus circulation in the European mink population and the clinical manifestations of the disease, comprehensive approaches to the disease diagnosis, including epidemiological studies, clinical and post-mortem examinations, molecular genetic laboratory diagnostics (polymerase chain reaction and full-genome sequencing) contributed to better understanding of the disease features. …”
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Lamb survivability: a new approach to an old problem by Carrie S. Wilson, Natalie L. Cherry, J. Bret Taylor

“…This study provides insight into within-litter competition for use in future genetic evaluation.…”
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Positioning a Handshake Bay for Twin Stacking Cranes in an Automated Container Terminal Yard Block by Zhi-Hua Hu, Xi-Dan Tian, Yu-Qi Yin, Chen Wei

“…To solve the model, we developed a random-key genetic algorithm with a priority-based decoding scheme to optimize the task sequences and tasks assigned to the cranes. …”
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A systematic review on malaria and Tuberculosis (TB) vaccine challenges in sub-Saharan African clinical trials. by Maonezi Abas Hamisi, Nur Ain Mohd Asri, Aini Syahida Mat Yassim, Rapeah Suppian

“…<h4>Conclusion</h4>Factors such as population characteristics, pathogen genetic diversity, vaccine nature, strategy, and formulation were associated with slow progress of the malaria and TB vaccine candidates in sub-Saharan African clinical trials.…”
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Issues of the Professional Development of Investigators of Pre-Trial Investigation Agencies of the National Police of Ukraine by N. E. Miloradova

“…Among the disadvantages of psychological support for passing consistent professional-genetic steps by investigators within the stage of professional development, the author has studied issues at the stages of professional adaptation (adaptant), mastering professional activity (intern), creative self-expression (master), mentoring (mentor), dismissal and social re-adaptation. …”
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Opportunities and Challenges for Pastoral Beef Cattle Production in Ethiopia by Belete Kuraz Abebe, Mulugeta Tesfaye Alemayehu, Sharew Mekonnen Haile

“…In contrast, problems with beef cattle production systems, diseases, shortages of feed and water, lack of veterinary services, droughts, lack of market access and infrastructure, illegal animal trades, and poor genetic potential of indigenous cattle are among the limiting factors that hamper efficient beef production in the country. …”
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Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases by Ya-Min Ma, Lan Zhao

“…In neurodegenerative diseases, in addition to the complex interactions between genetic susceptibility and environmental factors, miRNAs can serve as a promising diagnostic tool for diseases. …”
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Transactive energy management for efficient scheduling and storage utilization in a grid-connected renewable energy-based microgrid by Peter Anuoluwapo Gbadega, Olufunke Abolaji Balogun

“…Comparative analysis reveals that SMA consistently outperforms conventional methods such as Particle Swarm Optimization (PSO) and Genetic Algorithm (GA) in terms of convergence speed and computational efficiency, making it particularly suitable for real-time energy management. …”
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Humatch - fast, gene-specific joint humanisation of antibody heavy and light chains by Lewis Chinery, Jeliazko R. Jeliazkov, Charlotte M. Deane

“…However, the majority of antibody therapeutics are not genetically human, with initial therapeutic designs typically obtained from animal models. …”
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Brain-Derived Neurotrophic Factor Polymorphism and Aphasia after Stroke by Nathan T. Lee, Fatimah Ahmedy, Natiara Mohamad Hashim, Khin Nyein Yin, Kai Ling Chin

“…Studies have implicated Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene as a genetic factor influencing stroke recovery. Still, the role of BDNF polymorphism in poststroke aphasia is relatively unclear. …”
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Diagnosis of Methyl Malonicaciduria from 2013 to 2018 by Alina Concepción Álvarez, Ivette Camayd Viera, Norma Elena de León Ojeda, Alina García García, Laritza Martínez Rey, Daniel Quintana Hernández

“…<strong>Foundation:</strong> methylmalonic aciduria is one of the most frequent organic acidurias and groups together a set of genetic defects, characterized by the excretion of elevated levels of urinemethyl malonic acid. …”
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Forensic evaluation of craniometric characteristics of the Kazakhstan population by Saule A. Mussabekova, Anastasiya O. Stoyan, Xeniya E. Mkhitaryan, Saule B. Zhautikova

“…Background: The human skull is the part of the skeleton most frequently used in population studies, as it was more exposed to genetic factors and less exposed to environmental factors. …”
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Systemic lupus erythematosus in a patient with 22q11.2 deletion syndrome: A case report and review of the literature by Chen Sun, Pingyang Han, Juzhen Yan

“…Thymic dysplasia, T-cell lymphopenia, and B-cell abnormalities collectively contribute to the immunodeficiency and autoimmune manifestations observed in individuals with 22q11.2DS. Genetic factors such as 22q11.2DS should be considered in the diagnosis of childhood rheumatic diseases. …”
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A Dietary Treatment Improves Cerebral Blood Flow and Brain Connectivity in Aging apoE4 Mice by Maximilian Wiesmann, Valerio Zerbi, Diane Jansen, Roy Haast, Dieter Lütjohann, Laus M. Broersen, Arend Heerschap, Amanda J. Kiliaan

“…APOE ε4 (apoE4) polymorphism is the main genetic determinant of sporadic Alzheimer’s disease (AD). …”
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MicroRNA Deregulation in Anaplastic Thyroid Cancer Biology by Cesar Seigi Fuziwara, Edna Teruko Kimura

“…Anaplastic thyroid cancer (ATC) is among the most lethal types of cancers, characterized as a fast-growing and highly invasive thyroid tumor that is unresponsive to surgery and radioiodine, blunting therapeutic efficacy. Classically, genetic alterations in tumor suppressor TP53 are frequent, and cumulative alterations in different signaling pathways, such as MAPK and PI3K, are detected in ATC. …”
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A Novel on Energy Management Strategy with Maximum Exploitation of Renewables and EV Storage in Distribution Networks by K. Ramakrishna Reddy, C. H. Hussaian Basha, V. Prashanth, C. Dhanamjayulu, Sujata Shivashimpiger, R. Likhitha

“…The water filling algorithm (WFA) is utilized to distribute the storage of EVs in each energy zone in an optimal manner, thereby achieving load flattening, minimizing energy costs, and reducing grid reliance. A multiobjective genetic algorithm (MOGA) is employed to solve a formulated multiobjective optimization problem for load flattening and voltage regulation, with optimal power transaction (OPT) serving as the decision variable. …”
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Brazilian Thoracic Association recommendations for the management of lymphangioleiomyomatosis by Bruno Guedes Baldi, Paulo Henrique Ramos Feitosa, Adalberto Sperb Rubin, Alexandre Franco Amaral, Carolina Salim Gonçalves Freitas, Cláudia Henrique da Costa, Eliane Viana Mancuzo, Ellen Caroline Toledo do Nascimento, Mariana Sponholz Araujo, Marcelo Jorge Jacó Rocha, Martina Rodrigues de Oliveira, Tatiana Senna Galvão, Pedro Paulo Teixeira e Silva Torres, Carlos Roberto Ribeiro Carvalho

“…In recent decades, a number of advances have been made in the understanding of the pathophysiology and management of LAM, leading to improvements in its prognosis: identification of the main genetic aspects and the role of the mechanistic target of rapamycin (mTOR) pathway; relationship with hormonal factors, mainly estrogen; characterization of pulmonary and extrapulmonary manifestations in imaging studies; identification and importance in the diagnosis of VEGF-D; a systematic diagnostic approach, often without the need for lung biopsy; use of and indications for the use of mTOR inhibitors, mainly sirolimus, for pulmonary and extrapulmonary manifestations; pulmonary rehabilitation and the management of complications such as pneumothorax and chylothorax; and the role of and indications for lung transplantation. …”
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A Real-Time Timetable Rescheduling Method for Metro System Energy Optimization under Dwell-Time Disturbances by Guang Yang, Junjie Wang, Feng Zhang, Shiwen Zhang, Cheng Gong

“…The real-time feature and self-adaptability of the method are attributed to the combinational use of Genetic Algorithm (GA) and Deep Neural Network (DNN). …”
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Characterization of tumor evolution by functional clonality and phylogenetics in hepatocellular carcinoma by Zeynep Kacar, Eric Slud, Doron Levy, Julián Candia, Anuradha Budhu, Marshonna Forgues, Xiaolin Wu, Arati Raziuddin, Bao Tran, Jyoti Shetty, Yotsawat Pomyen, Jittiporn Chaisaingmongkol, Siritida Rabibhadana, Benjarath Pupacdi, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Chirayu Auewarakul, Suleeporn Sangrajrang, Chulabhorn Mahidol, Mathuros Ruchirawat, Xin Wei Wang

“…GTF2IRD2B mutations are enriched in HCC with linear evolution, while TP53 mutations are the most frequent genetic alterations in HCC with non-linear models. …”
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