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9321
The Role of the Endothelin System in the Vascular Dysregulation Involved in Retinitis Pigmentosa
Published 2015-01-01“…Retinitis pigmentosa is a clinical and genetic group of inherited retinal disorders characterized by alterations of photoreceptors and retinal pigment epithelium leading to a progressive concentric visual field restriction, which may bring about severe central vision impairment. …”
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9322
Clinical and Radiological Findings of Autosomal Dominant Osteopetrosis Type II: A Case Report
Published 2013-01-01“…Osteopetrosis is a rare inherited genetic disease characterized by sclerosis of the skeleton caused by the absence or malfunction of osteoclasts. …”
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9323
Transit Route Network Design for Low-Mobility Individuals Using a Hybrid Metaheuristic Approach
Published 2020-01-01“…Then, a hybrid metaheuristic approach based on ant colony and genetic algorithms is formulated to solve the proposed model in accordance with current conditions (i.e., existing routes that may need to undergo configuration adjustments to different degrees). …”
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9324
Replication of European hypertension associations in a case-control study of 9,534 African Americans.
Published 2021-01-01“…<h4>Conclusion</h4>These findings suggest that European-descent and AA populations share genetic loci that contribute to blood pressure traits and hypertension. …”
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9326
Illuminating the dynamic water–nitrogen relationship in rice via stable isotope techniques to improve cultivation
Published 2025-02-01“…Stable isotope analysis and modeling approaches were used to quantify the proportional contributions of various water sources to rice water uptake, considering both isotope discrimination and memory effects. Both N levels and genetic differences significantly influenced rice water uptake behavior, primarily through the functional characteristics of the root system. …”
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9327
Clinicopathological analysis of adrenal intravascular large B-cell lymphoma
Published 2024-11-01“…The clinical and histopathological features, immunophenotype, treatment and prognosis were analyzed. The molecular genetic characteristics were detected using next-generation sequencing (NGS). …”
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9328
Faktor Risiko Asma Pada Murid Sekolah Dasar Usia 6-7 Tahun di Kota Padang
Published 2012-11-01“…The occurrence of asthma is considered as a complex interaction between genetic factors and environmental factors. Genetic factors have been proved to be the risk factor for asthma, but not for the characteristic of environmental that factors that were still unclear. …”
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9329
Identification of QTL for Plant Height Traits in Single-segment Substitution Lines of Wild Rice
Published 2024-11-01“…Through fully exploring the elite genetic loci for plant height in wild rice, it would be helpful in the enrichment of dwarf genes and to provide new genetic resources for breeding rice varieties with ideal plant height.…”
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9331
University of Florida Potato Variety Trials Spotlight: ‘Peter Wilcox’
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9332
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Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients
Published 2025-01-01“…PurposeThe incidence of hemodynamic instability associated with dexmedetomidine (DEX) sedation has been reported to exceed 50%, with substantial inter-individual variability in response. Genetic factors have been suggested to contribute significantly to such variation. …”
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9336
Decreasing of heterogeneity in black tiger prawn (Penaeus monodon) and white shrimp (Litopenaeus vannamei) broodstocks and their fry produced in hatchery
Published 2009-01-01“… Domestication and genetic improvement of shrimp are required towards production of superior broodstock. …”
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9337
Familial Aggregation and Risk Factors for Prostate Cancer in Affected Individuals
Published 2024-10-01“…<strong>Foundation:</strong> prostate cancer is the second leading cause of death in men worldwide. Genetic studies indicate a link between certain genetic mutations, the aggressiveness of this neoplasia, the risk of developing the disease, and patient survival rates. …”
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9338
Identification of Novel GCK and HNF4α Gene Variants in Japanese Pediatric Patients with Onset of Diabetes before 17 Years of Age
Published 2021-01-01“…Common reasons for misdiagnosis are related to limitations in genetic testing. A precise molecular diagnosis is essential for the optimal treatment of patients and allows for early diagnosis of their asymptomatic family members. …”
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A current review on animal models of anti-asthmatic drugs screening
Published 2025-01-01“…This comprehensive review investigates the mechanisms and efficacy of anti-asthmatic drugs using both genetic and conventional animal models. Both genetic and traditional models of anti-asthmatic agents, their characteristics, and their significance are summarized as: In-Vitro Animal Models: Histamine receptor assay, Cell Culture Method, WST Assay, Spasmolytic Activity of the Lungs of Guinea Pigs, Airway and Vascular Responses to an Isolated Lung, The Isolated Perfused Guinea Pig Trachea’s Reactivity. …”
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HPK1 kinase inhibitor: a sufficient approach to target HPK1 to modulate T cell activation in cancer immunotherapy compared with degraders
Published 2025-02-01“…However, whether kinase inhibition is sufficient to eliminate the immunosuppressive function of HPK1, particularly in T cells, remains elusive.MethodsIn this study, genetic tools were used to edit the human T lymphocyte cell line Jurkat. …”
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