Association of Major Histocompatibility Complex Polymorphism With Acute Phase Response in Broiler Chicken by Afra Vatankhah, Gholamreza Nikbakht Brujeni, Atefeh Esmailnejad

“…ABSTRACT Background Stress associated with changes in host immunity occurs in response to altered environmental conditions, endogenous imbalances, infectious agents and harmful stimuli. The importance of genetic diversity in chickens has increased due to individual immune differences towards resistance and susceptibility to various stimuli. …”
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A Case Report of Aicardi-Goutières Syndrome Type 7 Caused by IFIH1 Gene Mutation and a Literature Review by ZHAO Min, SHU Zhou, HAN Tongxin, FU Yanhua, GAO Tianji, MAO Huawei

“…ObjectiveTo explore the clinical and genetic features of Aicardi-Goutières syndrome (AGS) caused by IFIH1 gene mutation.MethodsWe analyzed the clinical features and genetic mutation results of a boy with AGS type 7 and conducted a retrospective review of the literature of the characteristics and clinical features of IFIH1 gene mutations in AGS type 7.ResultsIn the case of this report, the patient, 13-year-old boy, exhibited gait abnormalities at age 3. …”
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Case report: an unusual long-term evolution of a diffuse midline glioma, H3K27 altered by Michael Griessmair, Michael Griessmair, Claire Delbridge, Claus Zimmer, Eva Mayr, Arthur Wagner, Julian Canisius, Marie-Christin Metz, Benedikt Wiestler, Benedikt Wiestler

“…BackgroundAs diffuse midline glioma, H3K27 altered, is a rare tumor entity with poor prognosis and few therapeutic options, only little is known so far about the genetic factors that influence tumorigenesis and the course of tumor development.PresentationWe present the case of a 38-year-old female patient who suffered from nausea, fatigue, and intermittent walking impairment, which developed over the course of four weeks. …”
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A cross-tissue transcriptome-wide association study identifies new susceptibility genes for benign prostatic hyperplasia by Li Wang, Si-yu Chen, Jian-wei Yang, Kang-yu Wang, Kun-peng Li, Shun Wan, Xiao-ran Li, Li Yang

“…Despite evidence of a significant genetic component from previous studies, the specific pathogenic genes and biological mechanisms are still largely unknown. …”
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Innovations in bioethanol production: A comprehensive review of feedstock generations and technology advances by Abeer Kazmi, Tahira Sultana, Amir Ali, Aneela Nijabat, Gaojie Li, Hongwei Hou

“…Batch, fed-batch, and continuous fermentation techniques are used, with advances such as immobilized cell reactors and genetic engineering improving output and efficiency. …”
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Clinical characteristics of and growth hormone treatment effects on short stature with type 1 insulin-like growth factor receptor (IGF1R) gene alteration by Yuki Kawashima-Sonoyama, Keisuke Wada, Kei Yamamoto, Masanobu Fujimoto, Noriyuki Namba, Takeshi Taketani

“…Owing to the lack of distinctive features, there was a possibility of undiagnosed cases of this condition. Promoting genetic testing and clinical trials on GH administration for this condition is recommended.…”
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New insights into interspecies relationships, chromosomal evolution, and hybrid identification in the Lycoris Herb. by Yue Zhang, Shujun Zhou, Yu Chen, Pengchong Zhang, Yongchun Zhang, Junhuo Cai, Zixuan Nie, Lu Zhang

“…Abstract Background Frequent interspecific hybridization, unclear genetic backgrounds, and ambiguous evolutionary relationships within the genus Lycoris pose significant challenges to the identification and classification of hybrids, thereby impacting the application and development of Lycoris. …”
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Generation of Inducible CRISPRi and CRISPRa Human Stromal/Stem Cell Lines for Controlled Target Gene Transcription during Lineage Differentiation by Li Chen, Kaikai Shi, Weimin Qiu, Lars Aagaard, Moustapha Kassem

“…However, mechanistic studies employing hMSC have been hampered by the difficulty of deriving genetically modified cell lines due to the low and unstable transfection efficiency. …”
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Prevalence of GCKR rs1260326 Variant in Subjects with Obesity Associated NAFLD and T2DM: A Case-Control Study in South Punjab, Pakistan by Tayyaba Nisar, Kashan Arshad, Zahid Abbas, Maira Ali Khan, Sohail Safdar, Rehan Sadiq Shaikh, Ali Saeed

“…This study was conducted to investigate the genetic association of the GCKR rs1260326 in NAFLD and T2DM in our population. …”
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IITA’s genebank, cowpea diversity on farms, and farmers’ welfare in Nigeria by Abel-Gautier Kouakou, Ademola Ogundapo, Melinda Smale, Nelissa Jamora, Julius Manda, Michael Abberton

“…Policymakers and practitioners should consider these findings when analyzing the benefits of conserving crop genetic diversity in genebanks and on farms.…”
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Effect of Sodium Azide on Quantitative and Qualitative Stem Traits in the M2 Generation of Ethiopian Sesame (Sesamum indicum L.) Genotypes by Micheale Yifter Weldemichael, Yemane Tsehaye Baryatsion, Desta Berhe Sbhatu, Girmay Gebresamuel Abraha, Hagos Mohammedseid Juhar, Abraha Birhan Kassa, Fiseha Baraki Sibhatu, Hailay Mehari Gebremedhn, Tesfakiros Semere Gebrelibanos, Mohammed Mebrahtu Mossa, Mullubrhan Mekonen Gebru, Birhanu Kahsay Meresa, Medhin Teklay, Birhanu Debesay Berhe, Haftay Abadi Gebru

“…Hence, this report would create more genetic diversity for further sesame genetic research improvements.…”
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Role of plasma metabolome in mediating the effect of plasma lipidome on NAFLD: a Mendelian randomization study by Zhuyuan Zheng, Shaojie Yang, Wanlin Dai, Yang Sun, Jingnan Wang, Xiaolin Zhang, Yiming Zheng, Jing Kong

“…No compelling proof was found that genetically predicted NAFLD influenced the risk of the five plasma lipidomes mentioned earlier. …”
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Peripheral nerve injury induces dystonia-like movements and dysregulation in the energy metabolism: A multi-omics descriptive study in Thap1+/− mice by Colette Reinhold, Susanne Knorr, Rhonda L. McFleder, Lisa Harder-Rauschenberger, Tom Gräfenhan, Andreas Schlosser, Michael Sendtner, Jens Volkmann, Chi Wang Ip

“…The incomplete penetrance of DYT-THAP1 dystonia, estimated at 40 to 60 %, suggests that an environmental trigger may be required for the manifestation of the disease in genetically predisposed individuals. To investigate the gene-environment interaction in the development of dystonic features, we performed a sciatic nerve crush injury in a genetically predisposed DYT-THAP1 heterozygous knockout mouse model (Thap1+/−). …”
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The relationship between histamine receptor type 4 gene polymorphism (rs11662595) and response to H1 antihistamine drugs in patients with chronic idiopathic urticaria by Ebrahim Mohammadi, Fakhredin Karimpour, Ramin Lotfi, Fatemeh Zamani, Abbas Aghaei, Rasoul Nasiri Kalmarzi

“…This study aimed to investigate the genetic frequency of the histamine receptor 4 gene polymorphism at SNP rs11662595 in individuals with chronic urticaria and their response to antihistamine treatment and side effects. …”
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S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasis by Panpan Lian, Li Li, Renwei Lu, Bin Zhang, Junaid Wazir, Chaode Gu, Bojie Ma, Wenyuan Pu, Wangsen Cao, Zhiqiang Huang, Zhonglan Su, Hongwei Wang

“…S1PR3 expression is markedly elevated in psoriatic lesions and correlates with disease severity. Using genetic and pharmacological approaches, we reveal a novel S1PR3–Src–STAT3 signaling axis that drives both early and prolonged STAT3 activation in keratinocytes. …”
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Novel primers drive accurate SYBR Green PCR detection of Listeria monocytogenes and Listeria innocua in cultures and mushrooms by Bo-eun Kim, Ravi Jothi, Da woon Kim, Dong Suk Park

“…Abstract The close genetic resemblance between Listeria monocytogenes and Listeria innocua, combined with their presence in similar environments, poses challenges for species-specific detection in food products. …”
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Loss of BRCA1 Spontaneously Induces the Tumorigenesis in Lacrimal Gland by Sun Eui Kim, Hye Jung Baek, Eun Jung Park, Sung Chul Lim, Sang Soo Kim

“…Environmental and genetic factors exert important influences on lifespan and neoplastic transformation. …”
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Associations and potential epigenetic changes between air pollution and osteoarthritis risk and survival: Insights from a prospective cohort study by Jing Qian, Jiahao Zhu, Yifan Wang, Ruoqi Dai, Jingyou Miao, Ye Yang, Wenxia Zhao, Jing Wang, Lilu Ding, Dan Zhou, Min Yu, Yingjun Li

“…Gene-environment interaction analyses were conducted to explore the potential modification effect of DNA methylation-related genetic variants on the impact of air pollution on OA risk. …”
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Genomic analysis and replication kinetics of the closely related EHV-1 neuropathogenic 21P40 and abortigenic 97P70 strains by Eslam Mohamed, Ines Zarak, Nick Vereecke, Sebastiaan Theuns, Kathlyn Laval, Hans Nauwynck

“…Both strains exhibited a nucleotide identity of 99.96%, with only seven genetic mutations in ORFs 13, 24, 30, 32, 40, 65, and 71. …”
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Detection of human noroviruses in sewage by next generation sequencing in Shandong Province, 2019–2021 by Suting Wang, Mingyi Xu, Xiaojuan Lin, Ping Xiong, Yao Liu, Aiqiang Xu, Meng Chen, Shengxiang Ji, Zexin Tao

“…Partial VP1 region was amplified and subjected to NGS analysis to assess the abundance and genetic characterization of various norovirus genotypes across different samples. …”
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