In Vivo Tracking of Chemokine Receptor CXCR4-Engineered Mesenchymal Stem Cell Migration by Optical Molecular Imaging by Senthilkumar Kalimuthu, Ji Min Oh, Prakash Gangadaran, Liya Zhu, Ho Won Lee, Ramya Lakshmi Rajendran, Se hwan Baek, Yong Hyun Jeon, Shin Young Jeong, Sang-Woo Lee, Jaetae Lee, Byeong-Cheol Ahn

“…Intravenous delivery of genetically modified MSCs overexpressing CXCR4 with a Fluc2 reporter gene may be a useful, noninvasive BLI imaging tool for tracking cell fate.…”
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A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new β-arrestin inhibitor by Rebecca L. Brouillette, Christine E. Mona, Michael Desgagné, Malihe Hassanzedeh, Émile Breault, Frédérique Lussier, Karine Belleville, Jean-Michel Longpré, Michel Grandbois, Pierre-Luc Boudreault, Élie Besserer-Offroy, Philippe Sarret

“…To study their functional role in regulating specific receptor systems, current research relies mainly on genetic tools, as few pharmacological options are available. …”
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High throughput phenotyping in soybean breeding using RGB image vegetation indices based on drone by Andressa K. S. Alves, Maurício S. Araújo, Saulo F. S. Chaves, Luiz Antônio S. Dias, Lucas P. Corrêdo, Gabriel G. F. A. Pessoa, André R. G. Bezerra

“…Significant genetic differences were identified among genotypes for all agronomic traits evaluated (p< 0.001), with high accuracy and heritability for plant height, maturity at R8, and 100-seed weight. …”
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Association of Maternal Diabetes Mellitus and Polymorphisms of the NKX2.5 Gene in Children with Congenital Heart Disease: A Single Centre-Based Case-Control Study by Mingyi Zhao, Jingyi Diao, Peng Huang, Jinqi Li, Yihuan Li, Yang Yang, Liu Luo, Senmao Zhang, Letao Chen, Tingting Wang, Ping Zhu, Jiabi Qin

“…These results suggest that maternal DM, NKX2.5 genetic variants, and their interactions are significantly associated with the risk of CHD in offspring.…”
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Characterization of subcutaneous and visceral de-differentiated fat cells by Yan Li, Houyu Zhang, Carlos F. Ibáñez, Meng Xie

“…Methods: Here, we used in vitro ''ceiling culture'', single cell/nucleus RNA sequencing, epigenetic anaysis and genetic lineage tracing to address these unknowns. …”
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Oil Content and Fatty Acid Composition of Safflower (<i>Carthamus tinctorius</i> L.) Germplasm by Cemal Kurt, Muhammad Tanveer Altaf, Waqas Liaqat, Muhammad Azhar Nadeem, Ayşe Nuran Çil, Faheem Shehzad Baloch

“…The protein percentage showed a high heritability but a low genetic advance, while palmitic acid, oil percentage, stearic acid, linoleic acid, palmitoleic acid, and oleic acid showed a high heritability and a moderate genetic advance as a percentage of the mean. …”
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CRISPR/Cas9-editing of PRNP in Alpine goats by Aurélie Allais-Bonnet, Christophe Richard, Marjolaine André, Valérie Gelin, Marie-Christine Deloche, Aurore Lamadon, Gwendoline Morin, Béatrice Mandon-Pépin, Eugénie Canon, Dominique Thépot, Johann Laubier, Katayoun Moazami-Goudarzi, Ludivine Laffont, Olivier Dubois, Thierry Fassier, Patrice Congar, Olivier Lasserre, Tiphaine Aguirre-Lavin, Jean-Luc Vilotte, Eric Pailhoux

“…In addition to KO alleles, a PRNP del6 genetic variant has been identified in one-third of founder animals. …”
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p53 dosage can impede KrasG12D- and KrasQ61R-mediated tumorigenesis. by Özgün Le Roux, Jeffery I Everitt, Christopher M Counter

“…Loss of the Trp53 gene encoding the tumor suppressor p53 enhances the ability of oncogenic Kras to initiate tumorigenesis in carcinogen and genetic models of lung cancer. Conversley, an extra copy of Trp53 (Super p53) was recently shown to suppress Kras-induced tumorigenesis in a genetic model of this disease. …”
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Single‐cell dissection reveals immunosuppressive F13A1+ macrophage as a hallmark for multiple primary lung cancers by Chenglin Yang, Jiahao Qu, Jingting Wu, Songhua Cai, Wenyi Liu, Youjun Deng, Yiran Meng, Liuqing Zheng, Lishen Zhang, Li Wang, Xiaotong Guo

“…Key points Comparative scRNA‐seq analysis reveals significant similarities in genetic, transcriptomicand immune profiles between MPLCs and SPLCs. …”
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Production of a new variant of soluble trimer Env of HIV-1 CRF63_02A6 SOSIP.664 by Nadezhda B. Rudometova, Andrey P. Rudometov, Anastasia A. Fando, Danil I. Vahitov, Alexander A. Ilyichev, Alexander P. Agafonov, Larisa I. Karpenko

“…The aim of the study was to obtain and characterize the stabilized trimer Env of HIV-1 SOSIP.664 based on the circulating genetic variant of the recombinant form CRF63_02A6. …”
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Optimizing in vitro introduction of wild common hop (Humulus lupulus L.) specimens using plant hormones by Olga V. Bychkova, Olga N. Mironenko, Elena P. Myakisheva, Inga Yu. Ivanova, Dmitry A. Dementiev

“…The ANOVA results confirmed that the genetic characteristics of the samples had the greatest impact on the reproduction rate and height of hop plants in vitro culture. …”
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Otsu’s Image Segmentation Algorithm with Memory-Based Fruit Fly Optimization Algorithm by Ruishuai Chai

“…However, the traditional genetic algorithm will fall into the local optimal solution in different degrees when finding the optimal threshold. …”
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The Usefulness of Genotyping of Celiac Disease-Specific HLA among Children with Type 1 Diabetes in Various Clinical Situations by Grazyna Deja, Dominika Sikora, Aleksandra Pyziak-Skupien, Karolina Klenczar, Rafał Deja, Przemysława Jarosz-Chobot

“…Results. The results of genetic tests confirmed the presence of DQ2/DQ8 in 94% of children with diabetes (group I) and in 100% of children with diabetes and CD (groups II and III, respectively). …”
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Allelic variation in an expansin, MdEXP-A1, contributes to flesh firmness at harvest in apples by Qiufang Su, Yifeng Feng, Xianglu Li, Zidun Wang, Yuanwen Zhong, Zhengyang Zhao, Huijuan Yang

“…These findings provide novel insight into the genetic control of flesh firmness by MdEXP-A1.…”
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Invasive Salmonella Typhimurium ST313 with naturally attenuated flagellin elicits reduced inflammation and replicates within macrophages. by Girish Ramachandran, Darren J Perkins, Patrick J Schmidlein, Mohan E Tulapurkar, Sharon M Tennant

“…Typhimurium ST313 strains have acquired pseudogenes and genetic deletions and appear to be evolving to become more like the typhoidal serovars S. …”
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The frequency of mutations in advanced thyroid cancer in Japan: a single-center study by Soji Toda, Hiroyuki Iwasaki, Yoichiro Okubo, Hiroyuki Hayashi, Mei Kadoya, Hiroyuki Takahashi, Tomoyuki Yokose, Yukihiko Hiroshima, Katsuhiko Masudo

“…We analyzed the outcomes of genetic testing to study the frequency of mutations in advanced thyroid cancer in Japan. …”
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Clinical Manifestation and Phylogenetic Analysis of Peste des Petits Ruminants in Local Iraqi Breed Sheep in Al-Diwaniyah Province by Khalefa A. Mansour, Muthanna H. Hussain, Saad H. Al-Husseiny, Asaad J. Abid, Qassim H. Kshash

“…This study found the Peste des Petits Ruminants (PPR) virus in sheep flocks in Al-Diwaniyah Governorate, Iraq, which is genetically similar to neighboring countries. PPR virus strains must be monitored and genetically characterized since N gene alterations can affect infection and propagation.…”
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In-silico screening and analysis of missense SNPs in human CYP3A4/5 affecting drug-enzyme interactions of FDA-approved COVID-19 antiviral drugs by Amro A. Abdelazim, Mohamad Maged, Ahmed I. Abdelmaksoud, Sameh E. Hassanein

“…Abstract Single nucleotide polymorphisms (SNPs) represent the prevailing form of genetic variations observed in the human population. …”
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Application of GA-BP Neural Network Optimized by Grey Verhulst Model around Settlement Prediction of Foundation Pit by C. Y. Liu, Y. Wang, X. M. Hu, Y. L. Han, X. P. Zhang, L. Z. Du

“…Due to the limitation in the prediction of the foundation pit settlement, this paper proposed a new methodology which takes advantage of the grey Verhulst model and a genetic algorithm. In the previous study, excavation times are often the only factor to predict the settlement, which is mainly because the correspondence between real-time excavation depth and the excavation time is hard to determine. …”
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Clinical Epidemiological Look at Patients with Congenital Heart Disease: a Study that has Become a Priority by Jan O´neil González Ramos, Nancy González Vales, Eida María Mena Albernal, Elsy Roxana Geroy Moya, Nicolás Ramón Cruz Pérez, Annia Quintana Marrero

“…Surgery was the predominant form of resolution, genetic diseases were the most frequent fetal risks. …”
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