Cyclophosphamide Pharmacogenomic Variation in Cancer Treatment and Its Effect on Bioactivation and Pharmacokinetics by Ibrahim El-Serafi, Sinclair Steele

“…Previous studies have shown the effect of the enzymes’ genetic polymorphisms on Cy kinetics and its clinical outcome. …”
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ZBiotics ameliorates T2DM-induced histopathological damage in liver, kidney and adipose tissues by modulating the NOD-like receptor signaling in Wistar rats by Mohammed Esawie, Marwa Matboli, Mariam Sameh Bushra, Amany H. Hasanin, Eman Kamal Habib, Reham Hussein Mohamed, Hebatalla Said Ali

“…In silico analysis was performed to construct a genetic-epigenetic network linked to STING-NOD pathway and autophagy signaling. …”
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A Mutation in IL4RA Is Associated with the Degree of Pathology in Human TB Patients by Christoph Hölscher, Lisa Heitmann, Ellis Owusu-Dabo, Rolf D. Horstmann, Christian G. Meyer, Stefan Ehlers, Thorsten Thye

“…Together, our genetic association study in human TB patients further supports the assumption that IL-13/IL-4Rα-dependent mechanisms are involved in mediating tissue pathology of human TB.…”
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Multi-Host of Ectomycorrhizal Fungi on Dipterocarpaceae in Tropical Rain Forests by Maliyana Ulfa, Eny Faridah, Su See Lee, Sumardi Sumardi, Christine le Roux, Antoine Galiana, Patahayah Mansor, Marc Ducousso

“…The most ectomycorrhizal fungi that play a role in multi-host are those with genetic relationship to the orders of Thelephorales, Russulales, and Sebacinales. …”
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Causal relationship between affect disorders and endometrial cancer: a Mendelian randomisation study by Yewu Sun, Shuo Geng, Chunmeng Fu, Xiaoyan Song, Hua Lin, Yidan Xu

“…Inverse variance-weighted, MR-Egger and weighted median MR analyses were performed, together with a range of sensitivity analyses.Results Mendelian randomisation analysis showed no statistically significant genetic responsibility effect of anxiety and stress-related disorders on any pathological type of endometrial cancer. …”
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A Boy With KIF11-Associated Disorder Along With ADHD and ASD: Collaboration Between Paediatrics and Child Psychiatry by Annelien Marcelis, Evelyne Van Reet

“…Moreover, gaining a deeper understanding of the higher prevalence of ASD and ADHD in individuals with KIF11 mutations could offer valuable insights into the genetic mechanisms underlying neurodevelopmental disorders.…”
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Effects of Single-Nucleotide Polymorphisms in Cytokine, Toll-Like Receptor, and Progesterone Receptor Genes on Risk of Miscarriage by Anastasiia Razdaibiedina, Mykhaylo Khobzey, Victoria Tkachenko, Iryna Vorobiova

“…Spontaneous abortion is a complex, multifactorial pathology, where various genetic, neural, endocrine, and immunological factors are involved. …”
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Constitutive expression of Cas9 and rapamycin-inducible Cre recombinase facilitates conditional genome editing in Plasmodium berghei by Samhita Das, Tanaya Unhale, Carine Marinach, Belsy del Carmen Valeriano Alegria, Camille Roux, Hélène Madry, Badreddine Mohand Oumoussa, Rogerio Amino, Shiroh Iwanaga, Sylvie Briquet, Olivier Silvie

“…Conventional reverse genetic tools cannot be used to study essential genes of the asexual blood stages, thereby necessitating the development of conditional strategies. …”
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Auditory evoked-potential abnormalities in a mouse model of 22q11.2 Deletion Syndrome and their interactions with hearing impairment by Chen Lu, Jennifer F. Linden

“…We exploited large inter-individual variation in hearing ability among Df1/+ mice to distinguish effects of genetic background from effects of hearing impairment. …”
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Evaluating the impact of smoking on the risk of dry eye disease: a two-sample Mendelian randomization study by Kuiliang Yang, Han Zhang, Yujin Wang, Yulin Yan, Zixian Yang, Shanshan Wan, Wanju Yang, Yanning Yang

“…Adhering to STROBE-MR guidelines, a MR analysis was conducted using genetic instrumental variables from Genome-wide association studies (GWAS). …”
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Assessment of Developmental Prosopagnosia in an Individual with Tourette Syndrome and Attention Deficit Hyperactivity Disorder: A Case Report by Petter Espeseth Emhjellen, Randi Starrfelt, Rune Raudeberg, Bjørnar Hassel

“…While ON’s DP, Tourette syndrome, and ADHD may have distinct genetic origins, impairment in face identity recognition has been observed across several neurodevelopmental conditions and is likely more common than currently thought.…”
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Oral phenotype and scoring of vascular Ehlers–Danlos syndrome: a case–control study by Lisa Golmard, Ariane Berdal, François Côme Ferré, Michael Frank, Bruno Gogly, Adrien Naveau, Hafida Chérifi, Joseph Emmerich, Frédérick Gaultier, Xavier Jeunemaitre, Benjamin P J Fournier

“…Objective Vascular Ehlers–Danlos syndrome (vEDS) is a rare genetic condition related to mutations in the COL3A1 gene, responsible of vascular, digestive and uterine accidents. …”
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Congenital malformations in children of epileptic pregnant women in the Cienfuegos province (2008-2018) by María Soledad Vilches León, Carmen Niurka Piña Loyola, Maylé Santos Solís, Vivian Rosa Vázquez Martínez, Cristóbal Jorge Torres González, Niurys Gonzales Cano

“…<br /><strong>Conclusion</strong>: the risk factors associated with congenital malformations in children of epileptic mothers were: maternal age over 35 years, history of previous pregnancy with malformation and genetic interruption of pregnancy.</p>…”
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Impact of Rs657152 Gene Polymorphisms on Inflammatory Markers in COVID-19 Patients With Type 2 Diabetes Mellitus by Ahmed Amshawee, Maryam A. Hussain

“…Understanding this genetic relationship is crucial for improving treatment strategies and predicting outcomes in this high-risk group. …”
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Multifaceted taxonomy of two Dactylogyrus species on Enteromius paludinosus: Integrating light microscopy, scanning electron microscopy and molecular approaches by Maduenyane Mpho, Dos Santos Quinton Marco, Avenant-Oldewage Annemariè

“…Soft tissues of SEM analysed specimens were genetically characterised using CO1 mtDNA, 18S-ITS1-5.8S rDNA and partial 28S rDNA fragments. …”
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Assessing the authenticity and purity of a commercial Bacillus thuringiensis bioinsecticide through whole genome sequencing and metagenomics approaches by Yari Van Laere, Yari Van Laere, Marie-Alice Fraiture, Andrea Gobbo, Sigrid C. J. De Keersmaecker, Kathleen Marchal, Kathleen Marchal, Nancy H. C. Roosens, Kevin Vanneste

“…., the absence of any undesired genetic material) of commercial Bacillus thuringiensis bioinsecticides. …”
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Identification of key regulators in pancreatic ductal adenocarcinoma using network theoretical approach. by Kankana Bhattacharjee, Aryya Ghosh

“…The disease's development involves complex interactions among immunological, genetic, and environmental factors, yet its molecular mechanism remains elusive. …”
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Association between dietary components and gut microbiota: a Mendelian randomization study by CHEN Haimiao, MA Yan, LIU Mingqi, MA Shanshan, LI Jun, XU Laichao

“…Conclusion: There are potential genetic and causal associations between dietary components and gut microbiota.…”
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A novel TGFBR2 mutation causes Loeys-Dietz syndrome in a Chinese infant: A case report by Xin Liu, Kaiqing Liu, Lifu Hu, Zixiao Liu, Xinhua Liu, Jiantao Wang

“…Conclusions: Our comprehensive genetic analysis suggested that the p.Glu335_Tyr336delinsAsp variant of TGFBR2 caused aberrant TGF-β signaling and contributed to LDS in the patient.…”
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Examining the Formalin Fixation Method for Maintaining High RNA Quality in Surgical Lung Specimens by Takashi Teishikata, Manabu Itoh, Yusuke Okamoto, Naofumi Miyahara, Chiho Nakashima, Koichiro Takahashi, Masafumi Hiratsuka, Keita Kai, Keiji Kamohara

“…ABSTRACT Background Multiplex genetic testing is recommended when treating nonsmall cell lung cancer. …”
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