Protocol for generating splice isoform-specific mouse mutants using CRISPR-Cas9 and a minigene splicing reporter by Yudong Teng, Kelsey Arbogast, Harald Junge, Zhe Chen

“…Splice isoform-specific mouse mutants provide valuable tools for genetic analyses beyond loss-of-function and transgenic alleles.For complete details on the use and execution of this protocol, please refer to Dailey-Krempel et al.1 and Johnson et al.2 : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.…”
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Effects of irrigation frequency on growth and yields of <i>Taraxacum kok-saghyz</i> Rodin by G. Shen, F. Zheng, L. Zhou, X. Zeng, N. G. Konkova

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Protocol for the purification and analysis of nuclear UFMylated proteins by Pudchalaluck Panichnantakul, Marlene Oeffinger

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THE STUDY OF THE NATURAL GENE POOL OF THE CAUCASUS’ PEARS IN THE ENVIRONMENTS OF ADYGEA by I. A. Bandurko, Z. Sh. Daguzhieva, E. M. Apukhtina

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Protective Effect of Cytosolic Phospholipase A2 Inhibition against Inflammation and Degeneration by Promoting Regulatory T Cells in Rats with Experimental Autoimmune Encephalomyeli... by Dan Yang, Hong-Fei Ji, Xue-Mei Zhang, Hui Yue, Lin Lin, Yu-Yan Ma, Xiang-nan Huang, Jin Fu, Wei-Zhi Wang

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The 1st International Conference of Wheat Landraces for Healthy Food Systems (June 13 - 15, 2018,University of Bologna, Italy) by Editorial Article

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Aspirin Resistance by Khaled Mansour, Ali T. Taher, Khaled M. Musallam, Samir Alam

“…The etiologic mechanism has been related to clinical, genetic, and other miscellaneous factors. The clinical implications of this phenomenon are significant and warrant concern. …”
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Coexistence of Ankylosing Spondylitis and Klinefelter's Syndrome by Şenol Kobak, Murat Yalçin, Muamer Karadeniz, Guray Oncel

“…Klinefelter's syndrome is a genetic condition that only affects males. Affected males have an extra X chromosome. …”
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Smart Fuzzing method based on comparison algorithm of control flow sequences by Ying WANG, Yi-xian YANG, Xin-xin NIU, Li-ze GU

“…Flowing the way introduced in the research of evolutionary fuzzing system (EFS),a smart fuzzing method was proposed based on the node comparison algorithm among control flow sequences.Through mapping program execution flow sequences onto the control flow sequences,the isomorphism relationship between dada search space and program logic space was established.The analyzed results prove that the method is capa of mining a mass of information from group data effectively,and is able to fully util ze the parallelism of genetic algorithm to guide the fuzzing test.…”
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Hemodynamic Instability after Low-Energy Thigh Contusion Caused by Injury to the Femoral Artery: A Case Report and Literature Review by Juan Miguel Rodríguez-Roiz, José Ballesteros-Betancourt, Raquel García-Tarriño, Victor Antonio Rodríguez-Roiz, Manuel Llusa

“…Arteriography was used to locate the point of bleeding, and embolisation and vessel occlusion were carried out to stop the haemorrhage. The genetic study identified the COL3A1 gene mutation; accordingly, the patient was diagnosed with the Ehlers-Danlos syndrome type IV (vascular type).…”
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La Ville-de-Montereau by Muriel Berthou Crestey

“…The iconographic study will be compared with the historical context and the textual genetic analysis.…”
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Research progress on the mechanisms of apolipoprotein E in Alzheimer’s disease by Jiayuan Li, Ting Liu, Shengxi Meng

“…Alzheimer’s disease (AD) is a degenerative disorder of the central nervous system that predominantly affects the elderly.The Apolipoprotein E (ApoE) gene is identified as the most significant genetic factor associated with AD.This article reviews current findings on the relationship between ApoE and AD, the impact of APOE gene polymorphisms on AD, the interaction between ApoE and other pathogenic factors, and the role of ApoE in AD.Additionally, it discusses the diagnosis and treatment of AD to enhance the understanding of its pathogenesis and to provide new perspectives for the prevention and management of the disease.…”
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Generalized Lichen Nitidus in Identical Twins by Alexander K. C. Leung, Jeffrey Ng

“…The familial occurrence of lichen nitidus suggests that a genetic factor may be operative.…”
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Genome-Wide Association Study of Hepatitis in Korean Populations by Youngbok Hong, Sejong Oh

“…In this study, we tried to find genetic factors for hepatitis through genome-wide association studies. …”
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Rehabilitation of Ectodermal Dysplasia Using CAD/CAM Mandibular Complete Denture and Maxillary Overdenture: A Clinical Report by Hatem Alqarni, Faisal Alzeghaibi, Sahar Alotaibi, Raghad Alamri, Raghad Aljohani, Majed S. Altoman, Mohammed A. Alfaifi

“…Ectodermal dysplasia is a genetic disorder characterized by the abnormal development of two or more ectodermally driven structures, leading to various clinical manifestations such as sparse hair, dry skin, and hypodontia or anodontia. …”
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A Hybrid IP/GA Approach to the Parallel Production Lines Scheduling Problem by Huizhi Ren, Shenshen Sun

“…Based on them, a hybrid integer programming/genetic algorithm (IP/GA) approach is proposed to solve the problem. …”
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Fulminant Disseminated Intravascular Coagulation as Initial Presentation of BRAF-Mutated Melanoma by Jeremy Chuang, An Uche, Rohan Gupta, Kim Margolin, Phyllis Kim

“…In our discussion, we highlight the current understanding of DIC and also identify opportunities for future research to elucidate the genetic aberrations in melanoma that may result in treatment resistance to combination therapy.…”
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Design, Simulation, and Optimization of an Irregularly Shaped Microstrip Patch Antenna for Air-to-Ground Communications by L. A. R. Ramirez, J. C. A. Santos

“…The process started with the design of a rectangular patch antenna with the traditional transmission line and cavity methods, followed by a simulation with the finite-difference time-domain method (FDTD) in conjunction with a genetic algorithm (GA). The aim of the study was to design an efficient patch antenna. …”
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An Enhanced Fractional Order Model of Ionic Polymer-Metal Composites Actuator by R. Caponetto, S. Graziani, F. Sapuppo, V. Tomasello

“…The minimization error was attained comparing the simple genetic algorithms with the simplex method and considering the error between the experimental and model derived frequency responses as cost functions.…”
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Urothelial Carcinoma in a 22-Year-Old Female with Angelman Syndrome by Jessica Pugh, R. Keith Huffaker

“…There is often a delay in diagnosis in younger individuals with different genetic mutations noted upon diagnosis.…”
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