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8761
Two-Echelon Location-Routing Problem with Time Windows and Transportation Resource Sharing
Published 2021-01-01“…Moreover, 20 small-scale instances are used for an algorithm comparison with multiobjective genetic algorithm and nondominated sorting genetic algorithm-II, and the solutions demonstrate the superiority of the proposed algorithm in optimizing logistics networks. …”
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8762
Genome Resequencing of the Honeybee Apis mellifera jemenetica (Hymenoptera: Apidae): A Key Tool towards Characterization, Conservation, and Genomic Selection
Published 2024-01-01“…Data revealed genome-wide patterns of genetic variation which can be useful in the characterization and assessment of positive selection of the Arabian honeybee using different genetic markers. …”
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8763
Integrated and streamlined microfluidic device for molecular diagnosis of pathogen through direct PCR amplification
Published 2025-01-01“…Background: Polymerase chain reaction (PCR) is a gold-standard method widely acknowledged for offering precise and rapid analysis of genetic material, particularly having a crucial role in detecting pathogens and diagnosing infectious diseases. …”
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8764
Ethnobotanical study of pumpkin (Cucurbita moschata Duchesne) landraces in Benin
Published 2021-09-01“…This abandonment could induce a risk of genetic erosion of this species. Thus, the conservation and an enhancement of the genetic resources of this species is essential. …”
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8765
Piezo1 aggravates ischemia/reperfusion-induced acute kidney injury by Ca2+-dependent calpain/HIF-1α/Notch signaling
Published 2025-12-01“…The main purpose of this study was to determine the role of macrophage Piezo1 in the injury and repair process in IR-AKI. Genetically modified mice with targeted knockout of Piezo1 in myeloid cells were established, and acute kidney injury was induced by bilateral renal vascular clamping surgery. …”
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8766
Investigation of the Molecular Mechanism of Asthma in Meishan Pigs Using Multi-Omics Analysis
Published 2025-01-01“…Asthma has been extensively studied in humans and animals, but the molecular mechanisms underlying asthma in Meishan pigs, a breed with distinct genetic and physiological characteristics, remain elusive. …”
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8767
Genome‐wide association study of tuberculosis in the western Chinese Han and Tibetan population
Published 2023-04-01“…Accumulated evidence has demonstrated that human susceptibility to TB has a strong genetic basis. And different susceptibility single nucleotide polymorphisms (SNP) have been reported in different studies. …”
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8768
Measuring Measuring iron concentration in the blood samples of some autistic children from Baghdad City
Published 2025-01-01“…Possible causes for this condition include specific drugs, genetic disorders, or the dietary habits of the ASD. …”
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8769
Pleiotropic effects of rabeprazole at acid-related diseases
Published 2018-08-01“…Conclusion. Interleukin genetic polymorphism investigation may be useful at assessment of cytokine status in AP patients to predict the outcomes and to develop the personalized approach to treatment and prophylaxis.…”
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8770
Innovative approaches in colorectal cancer screening: advances in detection methods and the role of artificial intelligence
Published 2025-01-01“…This review paper explored emerging detection methods for early screening of CRC, including gut microbiota, metabolites, genetic markers, and artificial intelligence (AI)-based technologies. …”
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8771
Type 1 Diabetes (T1D) and Latent Autoimmune Diabetes in Adults (LADA): The Difference Between a Honeymoon and a Holiday
Published 2022-01-01“…In young persons with a genetic predisposition, it usually manifests after being exposed to environmental triggers. …”
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8772
Production of recombinant norovirus VP1 protein and its antigenic and immunogenic properties
Published 2024-11-01“…Results and discussion. A genetic construct encoding recombinant VP1 of the GII genotype norovirus with codons optimized for highly effective expression in Escherichia coli has been created. …”
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8773
Contemporary Approaches to the Treatment of Gastroesophageal Reflux Disease
Published 2019-03-01“…The efficacy of PPI treatment may depend on the genetic polymorphism of the CYP2C19 cytochrome. Rabeprazole is characterized by a predominantly non-enzymatic pathway, providing a more stable pharmacokinetics profile, which is less dependent on the CYP2C19 polymorphism. …”
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8774
Comparative analysis of mitochondrial genomes of Stemona tuberosa lour. reveals heterogeneity in structure, synteny, intercellular gene transfer, and RNA editing
Published 2025-01-01“…This study provides a crucial genetic resource for evolutionary research within the genus Stemona and other related genera in the Stemonaceae family. …”
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8775
Drug delivery systems for oral cancer treatment: A patent perspective
Published 2024-03-01“…Major risk factors for oral cancer include tobacco and alcohol use, HPV infections, poor nutrition, and genetic susceptibility. The disease progresses through multiple genetic and epigenetic alterations involving tumor suppressors like p53, p16, and FHIT, along with oncogenes like EGFR, c-yc, K-ras, int-2, PRAD-1, and bcl leading to the development of premalignant lesions and subsequent tumors. …”
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8776
Antimicrobial Susceptibility of <i>Glaesserella parasuis</i> to Macrolides and Characterization of <i>erm</i>(T)-Carrying Mobile Elements on Chromosome
Published 2025-01-01“…Further analysis of these sequences revealed the genetic basis of macrolide resistance in <i>G. parasuis</i>. …”
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8777
A comprehensive overview of selective and novel fibroblast growth factor receptor inhibitors as a potential anticancer modality
Published 2024-03-01“…The arrival of comprehensive genome sequencing has accelerated the understanding of genetically aberrant advanced cancers and target identification for possible cancer treatment. …”
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8778
Dysmorphic Facial Features and Other Clinical Characteristics in Two Patients with PEX1 Gene Mutations
Published 2016-01-01“…Peroxisomal disorders are a group of genetically heterogeneous metabolic diseases related to dysfunction of peroxisomes. …”
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8779
Association between wide-ranging food intake and Parkinson’s disease: a comprehensive mendelian randomization study
Published 2025-01-01“…Abstract Parkinson’s disease (PD) is a complex neurodegenerative disorder influenced by both genetic and environmental factors, including dietary habits. …”
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8780
A Tissue Culture Technique for Rapid Clonal Propagation, Microrhizome Induction, and RAPD Analysis of <i>Kaempferia grandifolia</i> Saensouk & Jenjittikul—A Rare Plant Species in T...
Published 2024-12-01“…Micropropagated and field-grown donor plants of <i>K. grandifolia</i> showed 91.49% genetic similarity through RAPD analysis.…”
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