RCSD1-ABL1 Translocation Associated with IKZF1 Gene Deletion in B-Cell Acute Lymphoblastic Leukemia by Shawana Kamran, Gordana Raca, Kamran Nazir

“…Only a small number of RCSD1-ABL1 positive cases of B-ALL have been described in the literature, and the full spectrum of clinical, morphological, immunophenotypic, and molecular features associated with this genetic abnormality has not been defined. We describe extensive genetic characterization of a case of B-ALL with RCSD1-ABL1 fusion, by using conventional cytogenetic analysis, Fluorescence In Situ Hybridization (FISH) studies, and Chromosomal Microarray Analysis (CMA). …”
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Magnetic Nanoparticle Based Nonviral MicroRNA Delivery into Freshly Isolated CD105+ hMSCs by Anna Schade, Paula Müller, Evgenya Delyagina, Natalia Voronina, Anna Skorska, Cornelia Lux, Gustav Steinhoff, Robert David

“…Genetic modifications of bone marrow derived human mesenchymal stem cells (hMSCs) using microRNAs (miRs) may be used to improve their therapeutic potential and enable innovative strategies in tissue regeneration. …”
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Clinical, Radiographic, and Molecular Analysis of Patients with X-Linked Hypophosphatemic Rickets: Looking for Phenotype–Genotype Correlation by Marco A. Olivas-Valdez, Armando Blanco-López, Daniela Velázquez-Arestegui, Teresita Vera-Zazueta, Douglas Colmenares-Bonilla, Lilian Reyes-Morales, Miguel A. Blanco-Uriarte, Lucero Monterde-Cruz, Alberto Hidalgo-Bravo

“…Background/Objectives: X-linked hypophosphataemic rickets (XLH) represents the most frequent type of rickets from genetic origin, it is caused by mutations on the <i>PHEX</i> gene. …”
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Meta-QTL analysis for mining of candidate genes and constitutive gene network development for viral disease resistance in maize (Zea mays L.) by Mamta Gupta, Mukesh Choudhary, Alla Singh, Seema Sheoran, Harish Kumar, Deepak Singla, Abhishek Bohra, Sujay Rakshit

“…Viral diseases severely impact maize yields, with occurrences of maize viruses reported worldwide. Deployment of genetic resistance in a plant breeding program is a sustainable solution to minimize yield loss to viral diseases. …”
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Unusual Findings of Human-Associated Four-Nucleated <i>Entamoeba</i> Species in Captive Wild Animals by Lorena Esteban-Sánchez, Juan José García-Rodríguez, Francisco Ponce-Gordo

“…The identification of the <i>Entamoeba</i> species across diverse host species underscores the need for genetic confirmation to prevent misidentifications. …”
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The genomic architecture of circulating cytokine levels points to drug targets for immune-related diseases by Marek J. Konieczny, Murad Omarov, Lanyue Zhang, Rainer Malik, Tom G. Richardson, Sebastian-Edgar Baumeister, Jürgen Bernhagen, Martin Dichgans, Marios K. Georgakis

“…Our results provide an overview of the genetic architecture of circulating cytokines and could guide the development of targeted immunotherapies.…”
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Co-occurrence of a Mullerian anomaly and Kallmann syndrome: A case report by Lea C. George, Rebecca Gendelman, Anat Chemerinski, Pierre Lespinasse, Inessa A. Goldman, Sara Morelli

“…The evaluation of primary amenorrhea requires a thoughtful assessment for hormonal, structural and/or genetic causes. Although most cases of primary amenorrhea are caused by a single pathology, rarely multiple pathologies may be uncovered. …”
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Informatics strategies for early detection and risk mitigation in pancreatic cancer patients by Di Jin, Najeeb Ullah Khan, Wei Gu, Huijun Lei, Ajay Goel, Tianhui Chen

“…This emphasizes the need for targeted screening in high-risk groups, particularly those with familial predispositions and genetic mutations, such as BRCA1, BRCA2, and PALB2. …”
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Advancements in single-cell RNA sequencing and spatial transcriptomics: transforming biomedical research by Getnet Molla Desta, Getnet Molla Desta, Alemayehu Godana Birhanu

“…In recent years, significant advancements in biochemistry, materials science, engineering, and computer-aided testing have driven the development of high-throughput tools for profiling genetic information. Single-cell RNA sequencing (scRNA-seq) technologies have established themselves as key tools for dissecting genetic sequences at the level of single cells. …”
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ALCAM is an entry factor for severe community acquired Pneumonia-associated Human adenovirus species B by Yusang Xie, Hong Mei, Wei Wang, Xiao Li, Pengfei Hu, Xingui Tian, Rong Zhou, Jia Liu, Jieming Qu

“…Chimeric and authentic virus experiments show that ALCAM is a widely used host factor across B1 and B2 genetic clusters of HAdV-B. The dissociation constant between the knob domain of HAdV-B fiber and ALCAM is 837 nM in average. …”
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Accurate assembly of full-length consensus for viral quasispecies by Jia Tian, Ziyu Gao, Minghao Li, Ergude Bao, Jin Zhao

“…Reconstructing a robust consensus representation for these diverse mutant strains is essential for recognizing the genetic variations among strains and delving into aspects like virulence, pathogenesis, and selecting therapies. …”
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Generation of transgenic chicken through ovarian injection by Jinghua Jiang, Caiying Wang, Xuguang Du, Fei Gao, Sen Wu

“…Abstract Background Traditional DNA microinjection methods used in mammals are difficult to apply to avian species due to their unique reproductive characteristics. Genetic manipulation in chickens, particularly involving immature follicles within living ovaries, has not been extensively explored. …”
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Genome-wide association study and genomic selection of brace root traits related to lodging resistance in maize by Shaohang Lin, Xiaoming Xu, Zehui Fan, Jiale Jiang, Yukang Zeng, Yao Meng, Jiaojiao Ren, Penghao Wu

“…Abstract Brace roots are the primary organs for water and nutrient absorption, and play an important role in lodging resistance. Dissecting the genetic basis of brace root traits will facilitate breeding new varieties with lodging resistance and high yield. …”
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Perceptions and Practice of Early Diagnosis of Sickle Cell Disease by Parents and Physicians in a Southwestern State of Nigeria by Oladele Simeon Olatunya, Adefunke Olarinre Babatola, Ezra Olatunde Ogundare, Babatunde Ajayi Olofinbiyi, Olubunmi Adeola Lawal, Jacob Olumuyiwa Awoleke, Olusola Peter Aduloju, Alaba Olanrewaju Daramola, Eyitayo Ebenezer Emmanuel, Oyebanji Anthony Olajuyin, Akinwumi Kolawole Komolafe, Abiola Olukayode Olaleye

“…Amongst the mothers, 154 (94%) and 158 (96%) had encountered genetic counseling for SCD and were willing to offer newborn screening to their children, respectively. …”
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Human SLC26A1 Gene Variants: A Pilot Study by Paul A. Dawson, Pearl Sim, David W. Mudge, David Cowley

“…Why stones recur in many patients remains unknown but likely involves environmental, physiological, and genetic factors. The solute linked carrier (SLC) 26A1 gene has previously been linked to kidney stones in mice. …”
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Age-related cerebral ventriculomegaly occurs in patients with primary ciliary dyskinesia by Franziska Eisenhuth, Joy E. Agbonze, Adam M. R. Groh, Jesse M. Klostranec, David A. Rudko, Jo Anne Stratton, Adam J. Shapiro

“…Abstract Primary ciliary dyskinesia (PCD) is a genetic disorder causing motile ciliary dysfunction primarily affecting the respiratory and reproductive systems. …”
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Association between IFN-γ +874A/T and IFN-γR1 (-611A/G, +189T/G, and +95C/T) Gene Polymorphisms and Chronic Periodontitis in a Sample of Iranian Population by Zahra Heidari, Hamidreza Mahmoudzadeh-Sagheb, Mohammad Hashemi, Somayeh Ansarimoghaddam, Bita Moudi, Nadia Sheibak

“…The finding of this study showed that IFN-γ +874A/T gene polymorphism may affect susceptibility to CP, whereas IFN-γR1 genetic polymorphisms at -611A/G, +189T/G, and +95C/T were not associated with this disease.…”
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Characteristics and Risk Factors of Helicobacter pylori Associated Gastritis: A Prospective Cross-Sectional Study in Northeast Thailand by Taweesak Tongtawee, Soraya Kaewpitoon, Natthawut Kaewpitoon, Chavaboon Dechsukhum, Wilairat Leeanansaksiri, Ryan A. Loyd, Likit Matrakool, Sukij Panpimanmas

“…Risk factors for Helicobacter pylori infection are genetic susceptibility and poor living conditions. …”
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Molecular Identification, Histopathology and Antibiotic Susceptibility Profiling of Aeromonas veronii Isolated from Oreochromis niloticus in Bangladesh by Sayed Mashequl Bari, Mohammad Muttakinul Islam, Aktia Amina, Marufa Khatun, A. M. Shahabuddin

“…MT071624) in the NCBI BLAST search, and in the phylogenetic tree, they grouped in a single clade. This close genetic relationship is also supported by the low genetic distance between the isolates. …”
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Phylogeny of Macrobrachium spp. (Decapoda, Pleocyemata) from Peru based on mitochondrial and nuclear data reveals a species complex comprising M. digueti (Bouvier, 1895) and M. tra... by Eliana Zelada-Mázmela, Lorenzo E. Reyes-Flores, Luis De Stefano-Beltrán

“…Our analyses also corroborated the genetic proximity of sibling species M. inca–M. americanum and M. gallus–M. panamense, and the monophyletic origin of Macrobrachium species from Peruvian populations. …”
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