Diagnostic challenges in the diagnosis and treatment of ovarian cancer in Lynch syndrome by Agnieszka Protasiuk, Agata Żak, Rafał Sierzpowski, Patrycja Tymoszuk, Bartosz Kasperek, Katarzyna Augustowska

“… Introduction and purpose Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer (HNPCC), is an autosomal dominant genetic disorder characterized by a significantly increased risk of developing various malignancies, including ovarian cancer. …”
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Multiple Components of the VHL Tumor Suppressor Complex Are Frequently Affected by DNA Copy Number Loss in Pheochromocytoma by David A. Rowbotham, Katey S. S. Enfield, Victor D. Martinez, Kelsie L. Thu, Emily A. Vucic, Greg L. Stewart, Kevin L. Bennewith, Wan L. Lam

“…Indeed, little is known about genetic mechanisms disrupting other complex component genes. …”
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Heterogeneous phenotype of a Chinese Familial WHIM syndrome with CXCR4V340fs gain-of-function mutation by Yu Huang, Yu Huang, Yu Huang, Lu Li, Lu Li, Ran Chen, Ran Chen, Lang Yu, Lang Yu, Shunkai Zhao, Yanjun Jia, Yanjun Jia, Ying Dou, Ying Dou, Ying Dou, Zhiyong Zhang, Zhiyong Zhang, Yunfei An, Yunfei An, Xuemei Tang, Xuemei Tang, Xiaodong Zhao, Xiaodong Zhao, Lina Zhou

“…We provide an in-depth analysis of their clinical, genetic, immunological and treatment characteristic, noting that these patients exhibited an atypical clinical phenotype when compared to reported CXCR4R334X patients. …”
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Genomic insights into pigeon breeding: GWAS for economic traits and the development of a high-throughput liquid phase array chip by Bo Zhang, Jianyuan Ma, Li Shen, Yipu Li, Shuxian Xie, Haoxuan Li, Jing Li, Xianyao Li, Zheng Wang

“…This study integrates phenotypic data from Tarim pigeons and White King pigeons with genomic information, using genome-wide association analysis (GWAS) to identify genetic markers associated with key economic traits, thereby accelerating the breeding process. …”
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Chromosome-level genome assembly and annotation of Barbel chub Squaliobarbus curriculus by Qingmei Zheng, Feng Huang, Haiyan Zheng, Hui Zhang, Rushu Wen, Chao Li

“…Overall, the chromosome-level genome of S. curriculus will provide valuable genomic resources for genetic breeding, population genomics, sex-related marker identifications, and other future studies.…”
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Di-Genic Inheritance in Genodermatoses: Insights from Two Consanguineous Cases in a Reference Lebanese Center within the Middle East and North Africa (MENA) Region by Ayat Kadhi, Lamiaa Hamie, Edward Eid, Georges Nemer, Mazen Kurban

“… Introduction: Genodermatoses refer to a group of heterogenous rare genetic diseases with cutaneous expression. Several genodermatoses present with multisystem involvement that can range from mild to life-threatening conditions leading to increased morbidity and mortality. …”
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Multivariate Regression Analyses of Yield Associated Traits in Rapeseed (Brassica napus L.) Genotypes by Valiollah Rameeh

“…Significant genotypic effects were found for phenological traits, yield components, and seed yield, indicating significant genetic differences among the genotypes. High broad sense heritability was estimated for phenological traits, seeds per pod, and seed yield, signifying high selection gain for improving these traits. …”
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Chromosome-level genome assembly of Salvia sclarea by Sehyun Choi, Yuna Kang, Changsoo Kim

“…Despite its extensive use, the genetic mechanisms of S. sclarea are not well understood. …”
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Comparison of Adult Hippocampal Neurogenesis and Susceptibility to Treadmill Exercise in Nine Mouse Strains by Jong Whi Kim, Sung Min Nam, Dae Young Yoo, Hyo Young Jung, Il Yong Kim, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoon

“…The genetic background of mice has various influences on the efficacy of physical exercise, as well as adult neurogenesis in the hippocampus. …”
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Adult classic Bartter syndrome: a case report with 5-year follow-up and literature review by Le Jiang, Dongmei Li, Qiansha Guo, Yunfeng Li, Lei Zan, Rihan Ao

“…Distinguishing adult-onset BS from GS is challenging in clinical practice. However, genetic diagnosis can help solve this problem effectively, and genotypes play a guiding role in treatment planning.…”
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Demographic Trends in Korean Native Cattle Explained Using Bovine SNP50 Beadchip by Aditi Sharma, Dajeong Lim, Han-Ha Chai, Bong-Hwan Choi, Yongmin Cho

“…Linkage disequilibrium (LD) is the non-random association between the loci and it could give us a preliminary insight into the genetic history of the population. In the present study LD patterns and effective population size (Ne) of three Korean cattle breeds along with Chinese, Japanese and Mongolian cattle were compared using the bovine Illumina SNP50 panel. …”
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Vitiligo Review: etiopathogenesis, diagnosis and treatment by Aleksandra Witek, Jakub Parys, Agnieszka Mikosińska, Martyna Kaźmierczak, Maciej Mossakowski, Patrycja Kałuziak, Marta Jajczak, Mateusz Litwin, Stanisław Jesionek, RAfał Bieś

“…Its exact cause remains unclear, but genetic and environmental factors, such as stress and skin trauma, are thought to contribute. …”
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Beyond the Comfort Zone: Strenuous Sports as a Preventive Tactic Against Benign Prostatic Hyperplasia by Wei Zhang, Gang Li, Chengya Hao, Aijun Cheng

“…Strenuous sports are associated with an enlarged prostate. However, the genetic causality of this association remains unclear. …”
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Genomic adaptation of Clostridium perfringens to human intestine by Ke Wu, Juan Wang, Zelin Yan, Yanyan Zhu, Shaolin Wang, Bo Fu, Chengtao Sun, Ruichao Li, Edward M. Fox, Séamus Fanning, Li Bai, Yang Wang, Yizhi Tang, Zhe Yin, Rong Zhang, Hongning Wang

“…Through this comprehensive genomic analysis, we provide novel insights into the fusion of pCW3‐like and pCP13‐like plasmids, the genetic location of cpe, the transmission dynamics of C. perfringens strains, and the relationship between toxin genes and host relevance. …”
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Diversity of beetles (Arthropoda, Insecta, Coleoptera) associated with coniferous forests in Honduras by Mauricio Hernández, Mauricio Michel, Joel García, Geisy Dueñas, Marcela Moncada, Kevin Amaya, Yensi Yánez, Alejandra Pinto, Gabriela Matamoros, Alejandro Zamora, Gustavo Fontecha

“…Within I. apache, evidence of intraspecific genetic diversity was observed, although no population structure was detected. …”
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Increased FOXM1 Expression was Associated with the Prognosis and the Recruitment of Neutrophils in Endometrial Cancer by Jing Chen, Pusheng Yang, Shaojing Li, Yichen Feng

“…Bioinformatics analysis, including GEPIA, TIMER, cBioPortal, LinkedOmics, and STRING were used to analyze the FOXM1 gene expression, genetic alteration, and immune cell infiltration in EC. …”
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Implementation of CT Image Segmentation Based on an Image Segmentation Algorithm by Lingli Shen

“…Therefore, this study has proposed a combination of genetic algorithm (GA) and Great Law (OTSU) algorithm to form an image segmentation algorithm-immune genetic algorithm (IGA) algorithm. …”
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Venetoclax and Azacitidine Combination is an Effective Salvage Regimen for Fit Patients with IDH-2-mutated Acute Myeloid Leukemia Refractory to Conventional Induction Chemotherapy by Musa Fares Alzahrani

“…Acute myeloid leukemia (AML) constitutes a heterogeneous group of clonal myeloid neoplasms that is associated with a large number of recurrent genetic abnormalities. Mutations in IDH2 gene can be found in nearly 10% of newly diagnosed AML patients. …”
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Rare Suprasellar Chordoid Meningioma with INI1 Gene Mutation by Imad Fadl-Elmula, Rania Giha, Sawsan AH Deaf, Lamyaa Ahmed El Hassan, Ahmed M. Hassan, Mohamed AR Arbab

“…Background: Chordoid Meningioma is a rare brain tumour characterized genetically by loss of genetic material from chromosome 22q at cytogenetic level resulting in mutation of NF2 gene. …”
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Impact of the −174 G > C IL-6 Polymorphism on Bioelectrical Parameters in Obese Subjects after Laparoscopic Adjustable Gastric Banding by Laura Di Renzo, Maria Grazia Carbonelli, Alessia Bianchi, Emidio Domino, Maria Rita Migliore, Guido Rillo, Leonardo Iacopino, Nicola Di Daniele, Antonino De Lorenzo

“…Twenty obese subjects were selected and studied at baseline and 3 months after LAGB. Genetic assessment of −174 G>C IL-6 polymorphism and anthropometric and bioelectrical impedance analysis were performed. …”
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