Enriching Genomic Resources and Transcriptional Profile Analysis of Miscanthus sinensis under Drought Stress Based on RNA Sequencing by Gang Nie, Linkai Huang, Xiao Ma, Zhongjie Ji, Yajie Zhang, Lu Tang, Xinquan Zhang

“…Miscanthus × giganteus is wildly cultivated as a potential biofuel feedstock around the world; however, the narrow genetic basis and sterile characteristics have become a limitation for its utilization. …”
Get full text

Fasciclin 2 functions as an expression-level switch on EGFR to control organ shape and size in Drosophila. by Luis Garcia-Alonso

“…Loss-of-function genetic analysis shows that this Fasciclin 2 functional facet is required at the end of larval development and it is mediated by interaction with IgCAMs CG15630 (Fipi) and CG33543 (Elff). …”
Get full text

<i>Trypanosoma cruzi</i>: Genomic Diversity and Structure by Alfonso Herreros-Cabello, Francisco Callejas-Hernández, Núria Gironès, Manuel Fresno

“…Nowadays, new sequencing methods have improved some strains’ genome sequence and annotation, revealing this parasite’s extensive genetic diversity and complexity. In this review, we examine the genetic diversity, the genomic structure, and the principal multi-gene families involved in the pathogenicity of <i>T. cruzi</i>. …”
Get full text

Research note: A low-density SNP genotyping panel for Chinese native chickens by Jie Wang, Siyuan Xing, Yan Zhou, Jie Liu, Yan Sun, Qiuxia Lei, Haixia Han, Wei Liu, Dapeng Li, Fuwei Li, Dingguo Cao

“…The efficiency of molecular breeding largely depends on the cost of genotyping, which plays an important role in breeding and population genetic studies. Compared to pig, cattle, and sheep, poultry has a small size genome, and lower individual value. …”
Get full text

Intein-mediated split SaCas9 for genome editing in plants by Danling Hu, Lizhe Hu, Yaqiang Lu, Xiao Dong, Xingyu Cao, Shasha Bai, Lingang Zhang, Dongming Li, Yongwei Sun

“…Virus-induced genome editing (VIGE) technologies have been developed to address the limitations to plant genome editing, which heavily relies on genetic transformation and regeneration. However, the application of VIGE in plants is hampered by the challenge posed by the size of the commonly used gene editing nucleases, Cas9 and Cas12a. …”
Get full text

Molecular network analysis for detecting HIV transmission clusters: insights and implications by Yangyang Liu, Lichun Hua, Wenqian Wu, You Ge, Wei Li, Pingmin Wei

“…It helps with preventive and control methods by objectively identifying clusters with comparable genetic sequences, which enhances our knowledge of HIV transmission. …”
Get full text

Recapitulation of previously reported associations for type 2 diabetes and metabolic traits in the 126K East Asians by Ji-Young Choi, Hye-Mi Jang, Sohee Han, Mi Yeong Hwang, Bong-Jo Kim, Young Jin Kim

“…Over the last decade, genome-wide association studies (GWASs) have provided an unprecedented amount of genetic variations that are associated with various phenotypes. …”
Get full text

Giant Prolactinoma of Young Onset: A Clue to Diagnosis of MEN-1 Syndrome by Chandrika Jayakanthi Subasinghe, Noel Somasundaram, Pathmanathan Sivatharshya, Lalana Devi Ranasinghe, Márta Korbonits

“…High clinical suspicion upon unusual clinical presentation prompted genetic evaluation in these patients and detection of MEN1 gene mutation. …”
Get full text

Application of Proteomics to Inflammatory Bowel Disease Research: Current Status and Future Perspectives by Arash Assadsangabi, Caroline A. Evans, Bernard M. Corfe, Alan Lobo

“…Despite their important contribution to a better delineation of the disease process in IBD, these genetic findings have had little clinical impact to date. …”
Get full text

Environnement politique et réglementaire des pharmacultures au Canada : la contamination pharmaceutique à l’horizon ? by Marie-Hélène Bacon

“…Called pharma-crops, these new genetically modified organisms (GMO) could, among many other things, contaminate the food system and the environment. …”
Get full text

OrchidBase 6.0: increasing the number of Cymbidium (Orchidaceae) genomes and new bioinformatic tools for orchid genome analysis by You-Yi Chen, Ye Sun, Chung-I Li, Shao-Ting Lin, Hao-Chen Zheng, Zhe-Bin Zhang, Bing-Ru Lee, Chun-Lin Hsieh, Yu-Yun Hsiao, Chi-Nga Chow, Chien-Wen Yang, Wen-Chi Chang, Heming Chen, Feng-Xi Yang, Gen-Fa Zhu, Qinyao Zheng, Cheng-Yuan Zhou, Zhuang Zhao, Ye Ai, Lin-Ying Wang, Deqiang Chen, Xin He, Ming-Zhong Huang, Dong-Hui Peng, Hao Yu, Siren Lan, Zhong-Jian Liu, Wei-Sheng Wu, Wen-Chieh Tsai

“…Conclusion OrchidBase 6.0 extended genetic information to that of eight orchid species and created new tools for an expanded community curation in response to the ever-increasing volume and complexity of data.…”
Get full text

Generalized functional varying-index coefficient model for dynamic synergistic gene-environment interactions with binary longitudinal traits. by Jingyi Zhang, Honglang Wang, Yuehua Cui

“…The genetic basis of complex traits involves the function of many genes with small effects as well as complex gene-gene and gene-environment interactions. …”
Get full text

Expression of HGF and c-Met Proteins in Human Keratoconus Corneas by Jingjing You, Li Wen, Athena Roufas, Chris Hodge, Gerard Sutton, Michele C. Madigan

“…Taken together with the recent genetic studies, our results further support a possible role for HGF/c-Met in the pathogenesis of KC.…”
Get full text

Recent Advances in the Pathogenesis of Syndromic Autisms by A. Benvenuto, B. Manzi, R. Alessandrelli, C. Galasso, P. Curatolo

“…Background. Current advances in genetic technology continue to expand the list of medical conditions associated with autism. …”
Get full text

Is the Association Between TNF-α-308 A Allele and DMT1 Independent of HLA-DRB1, DQB1 Alleles? by Grazyna Deja, Przemyslawa Jarosz-Chobot, Joanna Polanska, Urszula Siekiera, Ewa Malecka-Tendera

“…The aim of the study was to assess chosen factors of genetic susceptibility to DMT1: DRB1, DQB1, and TNF-α polymorphisms-308 (G/A) in children with DMT1 and their up-to-now healthy siblings. …”
Get full text

Performance, methane production, and beef lipid profile of young bulls finished in feedlot by Barbara Martins Rodrigues, Ramon Costa Alvarenga, Dante Pazzanese Duarte Lanna, Alexandre Berndt, Fernando Antônio de Souza, Leandro Sâmia Lopes

“…The animal’s genetic composition modifies its fatty acid profile.…”
Get full text

Analysis of the Progress in Identification and Evaluation of Laboratory Animal Resources in China by DU Xiaoyan, LIU Yunbo

“…The paper further discusses related requirements for resource identification and evaluation, including population, genetic classification, biological characteristics, genetic stability, and application value. …”
Get full text

Association of HLA Genotype and Fulminant Type 1 Diabetes in Koreans by Soo Heon Kwak, Yoon Ji Kim, Jeesoo Chae, Cue Hyunkyu Lee, Buhm Han, Jong-Il Kim, Hye Seung Jung, Young Min Cho, Kyong Soo Park

“…Although we had limited statistical power, we provide evidence that HLA haplotype and amino acid change can be a genetic risk factor of fulminant T1DM in Koreans. …”
Get full text

Variants in the 3′ End of SLC6A3 in Northwest Han Population with Parkinson’s by Peiye Chang, Yongwang Fu, Ping Zhao, Chunmei Wang, Mingfang Jiang, Rui Li, Yulin He

“…It is possible that multifactorial and genetic factors are related to its pathogenesis. Recently, there have been reports of SLC6A3 genetic variants leading to PD. …”
Get full text

Human migration from the Levant and Arabia into Yemen since Last Glacial Maximum by Andreas Henschel, Riyadh Saif-Ali, Molham Al-Habori, Syafiq Azman Kamarul, Luca Pagani, Cynthia Al Hageh, Emilio Porcu, Nassim Nicolas Taleb, Daniel Platt, Pierre Zalloua

“…We show that the initial gene flow into the Yemeni populations of today came from the rest of Arabia and the Levant, and a less substantial and more recent genetic impact into coastal Yemen from East Africa, particularly.…”
Get full text