North American apple-tree species: sources of useful agronomic traits for breeding by O. N. Barsukova

Get full text

Identification of positive selection signatures associated with milk and composition traits in Murciano-Granadina and Barki by Hossein Mohammadi, amir hossien khaltabadi farahani, Mohammad Hossein Moradi

“…Using these findings can accelerate the genetic progress in the breeding programs and can be used to understand the genetic mechanism controlling this trait. …”
Get full text

Non-Viral Delivery Systems to Transport Nucleic Acids for Inherited Retinal Disorders by Md Jobair Jony, Ameya Joshi, Alekha Dash, Surabhi Shukla

“…Inherited retinal disorders (IRDs) represent a group of challenging genetic conditions that often lead to severe visual impairment or blindness. …”
Get full text

CHEK2∗1100delC Mutation and Risk of Prostate Cancer by Victoria Hale, Maren Weischer, Jong Y. Park

“…Although the causes of prostate cancer are largely unknown, previous studies support the role of genetic factors in the development of prostate cancer. …”
Get full text

Increased prevalence of recurrence in squamous cell carcinoma arising from buccal mucosa: A pervasive threat requiring multidimensional perspectives by Thilaga Duraisamy, Ramya Ramadoss, Suganya Panneer Selvam, Sandhya Sundar, Nitya Krishnasamy, Hemashree

“…Discussion: Anatomic, genetic, environmental, and lifestyle factors contribute to its resurgence. …”
Get full text

DNA barcoding and antioxidant activity of Fritillaria karelinii (Fisch. ex D. Don) Baker from nature habitats of southeast Kazakhstan by A. Tursynbay, S. Jo, Z.Z. Karzhaubekova, N.G. Gemejiyeva, J.-H. Paik, A.G. Sankaybaeva, G.S. Mukan

“…Don) Baker was reconstructed and analyzed to confirm its genetic identification and phylogenetic position. …”
Get full text

OPTIMIZATION DESIGN OF INTERNAL GEAR PUMP BASED ON IMPROVED PARTICLE SWARM OPTIMIZATION by SUN YuanJing, QI ZhiYuan, ZHAO GuoChao

“…The improved particle swarm optimization was obtained by introducing the genetic operation and mutation operation of the genetic algorithm into the particle swarm optimization algorithm,through this algorithm、the parameters of gear indexing circle pressure angle、modification coefficient、addendum coefficient and tooth number were optimized,and the gear parameters of gear pump with minimum flow pulsation rate were obtained. …”
Get full text

Periodontitis and Rheumatoid Arthritis: The Same Inflammatory Mediators? by Fulvia Ceccarelli, Matteo Saccucci, Gabriele Di Carlo, Ramona Lucchetti, Andrea Pilloni, Nicola Pranno, Valeria Luzzi, Guido Valesini, Antonella Polimeni

“…The aim of the review is to summarize this issue. Starting from genetic factors, data from literature demonstrated the association between HLA-DRB1 alleles and PD susceptibility, similar to RA patients; moreover, SE-positive patients showed simultaneously structural damage to the wrist and periodontal sites. …”
Get full text

A Design of Parameters with Supercritical Carbon Dioxide Brayton Cycle for CiADS by Yichuan He, Aihua Dong, Min Xie, Yang Liu

“…The influences of the key parameters on thermodynamic properties of SCO2 Brayton Cycle are discussed and the comparative analyses on genetic algorithm and pattern search algorithm are conducted. …”
Get full text

Sanjad-Sakati Syndrome Dental Management: A Case Report by Hisham Y. El Batawi

“…Sanjad-Sakati syndrome (SSS) is a rare genetic disorder with autosomal recessive pattern of inheritance characterized by hypoparathyroidism, sever growth failure, mental retardation, susceptibility to chest infection, and dentofacial anomalies. …”
Get full text

Familial Prevalence of Inflammatory Bowel Disease in Northern Alberta by BR Pinchbeck, J Kirdeikis, ABR Thomson

“…This high familial prevalence of Crohn's disease and ulcerative colitis suggests that genetic factors could play a role in the development of these disorders. …”
Get full text

Herpes Simplex Virus Latency: The DNA Repair-Centered Pathway by Jay C. Brown

“…The pathway is particularly attractive because it is able to account for important features of the latent response, including the specificity for neurons, the specificity for neurons of the peripheral compared to the central nervous system, the high rate of genetic recombination in HSV1-infected cells, and the genetic identity of infecting and reactivated virus.…”
Get full text

Recombinant human growth hormone treatment of Floating-Harbor syndrome: a case report and literature review by Qing He, Yi Deng, Lei Xu, Zhe Xu, Yi Ding, Menghui Wu

“…Abstract Background Floating Harbor syndrome (FHS) is a rare genetic disorder with over 100 reported cases worldwide and less than 30 treated with recombinant human growth hormone (rhGH). …”
Get full text

Short-term evolutionary implications of an introgressed size-determining supergene in a vulnerable population by Pierre Lesturgie, John S. S. Denton, Lei Yang, Shannon Corrigan, Jeff Kneebone, Romuald Laso-Jadart, Arve Lynghammar, Olivier Fedrigo, Stefano Mona, Gavin J. P. Naylor

“…Coalescent-based demographic modelling reveals strong migration between regions maintaining genetic variability in the recombining genome, preventing speciation between morphs. …”
Get full text

Damage Detection of a Continuous Bridge from Response of a Moving Vehicle by Z. H. Li, F. T. K. Au

“…At the second stage, the identification problem is transformed into a global optimization problem and is solved by genetic algorithm techniques. For each pass of the vehicle, the method can identify the location of the damage until it is determined with acceptable accuracy. …”
Get full text

The Contribution of the Cerebellum to Cognition in Spinocerebellar Ataxia Type 6 by Freya E. Cooper, Manon Grube, Kelly J. Elsegood, John L. Welch, Thomas P. Kelly, Patrick F. Chinnery, Timothy D. Griffiths

“…This study sought evidence for a specific cerebellar contribution to cognition by characterising the cognitive phenotype of Spinocerebellar Ataxia Type 6 (SCA-6); an autosomal dominant genetic disease which causes a highly specific late-onset cerebellar degeneration. …”
Get full text

Role of ARMS2/HTRA1 risk alleles in the pathogenesis of neovascular age-related macular degeneration by Yang Pan, Takeshi Iwata

“…AMD is a multifactorial disease mainly caused by advanced age, environmental factors, and genetic variations. Genome-wide association studies (GWAS) have strongly supported the link between ARMS2/HTRA1 locus on chromosome 10q26 and AMD development, encompassing multiple variants, rs10490924 (c.205G > T, p.A69S in ARMS2), insertion/deletion (del443/ins54 in ARMS2), and rs11200638 (in HTRA1 promoter region). …”
Get full text

D(—)–Lactic Acid Producing Probiotics, D(—)–Lactic Acidosis and Infants by David R Mack

“…Furthermore, gene-environmental interactions are considered to be important in the development of disease in those at genetic risk. With the intestinal tract harbouring large numbers of bacteria, alteration of the microbial environment with probiotic microbes is being considered as a controllable factor that may limit disease expression for those at genetic risk. …”
Get full text

Cement Transport Vehicle Routing with a Hybrid Sine Cosine Optimization Algorithm by Vu Hong Son Pham, Van Nam Nguyen

“…To demonstrate the advantages of the developed hybrid sine cosine algorithm, this algorithm is evaluated and compared with modern algorithms such as sine cosine algorithm, dragonfly algorithm, grey wolf optimizer, ant lion optimizer, particle swarm optimization, modified hybrid particle swarm optimization, genetic algorithm, and the double-population genetic algorithm in case studies. …”
Get full text

Neonatal necrotizing enterocolitis complicated by glutaric acidemia type II: a case report by Yuli Zhang, Yuli Zhang, Longfei Chen, Miao Duan

“…Glutaric acidemia type II (GAII) is an autosomal recessive genetic metabolic disorder associated with mitochondrial dysfunction, characterized by multiple acyl-CoA dehydrogenase deficiency that affects fatty acid metabolism. …”
Get full text