Cardio-metabolic-related plasma proteins reveal biological links between cardiovascular diseases and fragility fractures: a cohort and Mendelian randomisation investigationResearch... by Karl Michaëlsson, Rui Zheng, John A. Baron, Tove Fall, Alicja Wolk, Lars Lind, Jonas Höijer, Carl Brunius, Eva Warensjö Lemming, Olga E. Titova, Bodil Svennblad, Susanna C. Larsson, Shuai Yuan, Håkan Melhus, Liisa Byberg, Hannah L. Brooke

“…The genetically determined concentration of nine proteins influenced fat mass, and one influenced lean body mass. …”
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Keratoconus with two consecutive re-emergences: a case report by Peicheng Zhang, Yanchao Wu, Lixiao Ma, Dong Wang

“…Conclusions Keratoconus is a complex disorder with a multifaceted etiology and pathogenesis, including genetic, environmental, biomechanical, and cellular factors. …”
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Aflatoxin B1 impairs the growth and development of chicken PGCs through oxidative stress and mitochondrial dysfunction by Ying-Jie Niu, Jun Wu, Wenjie Ren, Guangzheng Liu, Gaoyuan Wu, Yixiu Peng, Dan Zheng, Kai Jin, Qisheng Zuo, Guohui Li, Wei Han, Xiang-Shun Cui, Guohong Chen, Bichun Li

“…Primordial germ cells (PGCs) in chickens, as ancestral cells of gametes, are essential for genetic transmission, yet the impact and mechanisms of aflatoxins on them remain elusive. …”
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MtCro: multi-task deep learning framework improves multi-trait genomic prediction of crops by Dian Chao, Hao Wang, Fengqiang Wan, Shen Yan, Wei Fang, Yang Yang

“…Abstract Genomic Selection (GS) predicts traits using genome-wide markers, speeding up genetic progress and enhancing breeding efficiency. …”
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Reproductive modes in populations of late-acting self-incompatible and self-compatible polyploid Ludwigia grandiflora subsp. hexapetala in western Europe by Stoeckel, Solenn, Becheler, Ronan, Portillo-Lemus, Luis, Harang, Marilyne, Besnard, Anne-Laure, Lassalle, Gilles, Causse-Védrines, Romain, Michon-Coudouel, Sophie, Park, Daniel J., Pope, Bernard J., Petit, Eric J., Barloy, Dominique

“…., the proportion of individuals produced by clonality, selfing and outcrossing in populations, determines how hereditary material is transmitted through generations. It shapes genetic diversity and its structure over time and space, which can be used to infer reproductive modes. …”
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Functional analysis of heterozygous variants in the SALL1 gene in 2 children with Townes-Brocks syndrome with FSGS by Rong Liang, Bixia Zheng, Chunli Wang, Sanlong Zhao, Wei Zhou, Ying Chen, Ruochen Che

“…The genetic function was investigated through cultured cells transfected with variants. …”
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Nanoparticle-mediated gene delivery techniques in plant systems by Kuber Shivashakarappa, Sureshbabu Marriboina, Korsi Dumenyo, Ali Taheri, Zeinab Yadegari

“…Gene delivery is an essential step in plant genetic transformation, and it is largely plant species-specific. …”
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Diabetes and tuberculosis: a systematic review and meta-analyis of mendelian randomization evidence by Ivaan Pitua, Raafidha Raizudheen, Mark Muyanja, Joseph Nyero, Morrish Okello Obol

“…Mendelian randomization (MR) offers a method to assess causality by leveraging genetic variants as instrumental variables, mitigating biases from confounding and reverse causation. …”
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Making Dementia Matter Through Sound by Marjolein Gysels, Chris Tonelli, Thomas Johannsen

“… This paper investigates the working practices of the Genetic Choir and the “Stem&Luister” project, in which the ensemble uses voice, sound and improvisation to explore and develop ways of connecting with people with dementia, thereby seeking to improve the experience of care. …”
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Kartagener Syndrome: A Rare Cause of Infertility by Kadir Bakay, Davut Güven, İdris Koçak

“…Kartagener’s syndrome is defined as motility dysfunction of the epithelial cilia lining the respiratory tract, fallopian tubes and the flagella of the sperm and genetically classified as a rare autosomal recessive disease consisting almost half of all primary ciliary dyskinesia cases. …”
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Hypercalcemia and co-occurring TBX1 mutation in Glycogen Storage Disease Type Ib: case report by Zakaria Kasmi, Imane Ain El Hayat, Zahra Aadam, Abderrahmane Errami, Ibtihal Benhsaien, Jalila EL Bakkouri, Dalal Ben Sabbahia, Meryem Atrassi, Ahmed Aziz Bousfiha, Fatima Ailal

“…These findings add a new dimension to our understanding of GSD-Ib and suggest potential avenues for future research to elucidate these genetic interactions and their impact on clinical outcomes.…”
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Multi-omic spatial effects on high-resolution AI-derived retinal thickness by V. E. Jackson, Y. Wu, R. Bonelli, J. P. Owen, L. W. Scott, S. Farashi, Y. Kihara, M. L. Gantner, C. Egan, K. M. Williams, B. R. E. Ansell, A. Tufail, A. Y. Lee, M. Bahlo

“…Analysis of common genomic variants, metabolomic, blood and immune biomarkers, disease PheCodes and genetic scores across a fine-scale macular thickness grid, reveals multiple novel genetic loci including four on the X chromosome; retinal thinning associated with many systemic disorders including multiple sclerosis; and multiple associations to correlated metabolites that cluster spatially in the retina. …”
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Comparative study of stability models for identifying stable spring wheat genotypes in diverse conditions by Vijay Kamal Meena, Ram Kumar Sharma, Subhash Chand, Shahil Kumar, Kapil Choudhary

“…Abstract To assess the agronomic performance and genetic stability for grain yield, a set of 36 spring wheat genotypes were grown consecutively for two crop seasons in six environments with varying sowing dates at ICAR-Indian Agricultural Research Institute, New Delhi using randomized complete block design with three replications. …”
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Pulmonary artery aneurysm as a rare manifestation of Alpha-1 antitrypsin deficiency by Mark A. Colantonio, Sanjana Aggarwal, Himanshu Deshwal

“…Alpha-1 antitrypsin is a relatively well-known genetic disease known to primarily affect the lungs and liver. …”
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Kenosis o la idea de Dios en mí en el ritual del Santo Daime by Mauricio Genet Guzmán Chávez

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New aspects of non-alcoholic fatty liver disease by V. V. Tsukanov, E. V. Kasparov, Yu. L. Tonkikh, A. V. Vasyutin

“…To analyze modern data on pathogenesis and principles of treatment of non-alcoholic fatty liver disease (NAFLD).Key points. Now concepts on genetic determinants of NAFLD and diagnostics methods develop rapidly. …”
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CRISPR Gene Editing in Strawberry by Seonghee Lee, Cheolmin Yoo, Kevin M. Folta, Vance Whitaker

“… Because cultivated strawberries are genetically complex, conventional breeding of strawberry can be difficult. …”
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CRISPR Gene Editing in Strawberry by Seonghee Lee, Cheolmin Yoo, Kevin M. Folta, Vance Whitaker

“… Because cultivated strawberries are genetically complex, conventional breeding of strawberry can be difficult. …”
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Results of Selective Biochemical Screening for Lysosomal Acid Lipase Deficiency and Sequencing of the <i>LIPA</i> Gene in the Risk Group Patients by S. V. Shtykalova, A. A. Egorova, O. S. Glotov, A. V. Kiselev, I. Yu. Kogan

“…In 100 % of detected cases, genetic mutations in the LIPA gene included single nucleotide substitution c.894G&gt;A. …”
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Inter- and intra-varietal clonal differences influence the aroma compound profiles of wines analyzed by GC–MS and GC-IMS by Huawei Chen, Shijian Bai, Bowei Yang, Ruihua Ren, Zizhu Tang, Zhenwen Zhang, Qingqing Zeng

“…These findings address the research gap concerning the genetic determinants of wine aroma, highlighting the significance of grape variety and clone selection in developing wines with desirable sensory attributes.…”
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