A Survey of SNP Data Analysis by Xiaojun Ding, Xuan Guo

“…Each SNP explains only a small fraction of genetic causes. Experiments on individual SNPs may reveal their non-detectable effects on complex diseases. …”
Get full text

An insight into the genome-wide analysis of bacterial defense mechanisms in a uropathogenic Morganella morganii isolate from Bangladesh. by Syed Muktadir Al Sium, Barna Goswami, Sanjana Fatema Chowdhury, Showti Raheel Naser, Mihir Kanti Sarkar, Md Jobaid Faruq, Md Ahashan Habib, Shahina Akter, Tanjina Akhtar Banu, Md Murshed Hasan Sarkar, Md Salim Khan

“…For the development of targeted treatments and preventing the onset of resistance in clinical care, it is essential to comprehend these genetic fingerprints.…”
Get full text

Infection Frequency and Allelic Variants of <em>Toxoplasma gondii</em> in Wildlife from the Panama Canal Zone by Evelyn Henríquez-Carrizo, Hector Cruz, Alessandra Jurado, Diorene Smith, Delba Villalobos-Cerrud, Lorena Fábrega, Carolina de la Guardia, Ryan Cano, Ricardo Correa, Edy Frías, Anabel Argelis García, Nivia Ríos, Nidia Sandoval, Alex O. Martínez Torres, Armando Castillo-Pimentel, Zuleima Caballero E.

“…Panama has a large number of wild animal species, which could host a highly diverse amount of genetic variants of <i>Toxoplasma gondii</i> (<i>T. gondii</i>). …”
Get full text

Deletions of N33, STK11 and TP53 Are Involved in the Development of Lymph Node Metastasis in Larynx and Pharynx Carcinomas by Marta Alonso Guervós, César Álvarez Marcos, Mario Hermsen, Andrés Sampedro Nuño, Carlos Suárez, José Luis Llorente

“…Background: Lymph node metastasis is the mayor cause of mortality in patients with head and neck squamous cell carcinomas (45%). The genetic changes underlying metastasis are still largely unknown and genetic markers to predict lymph node positivity still need to be found. …”
Get full text

Variations in the Obesity Gene “LEPR” Contribute to Risk of Type 2 Diabetes Mellitus: Evidence from a Meta-Analysis by Ming Ming Yang, Jun Wang, Jiao Jie Fan, Tsz Kin Ng, Dian Jun Sun, Xin Guo, Yan Teng, Yan-Bo Li

“…A number of studies have evaluated the genetic effect of leptin (LEP) and leptin receptor (LEPR) genes on T2DM. …”
Get full text

Florfenicol Resistance in Enterobacteriaceae and Whole-Genome Sequence Analysis of Florfenicol-Resistant Leclercia adecarboxylata Strain R25 by Yuanyuan Ying, Fei Wu, Chongyang Wu, Yi Jiang, Min Yin, Wangxiao Zhou, Xinyi Zhu, Cong Cheng, Licheng Zhu, Kewei Li, Junwan Lu, Teng Xu, Qiyu Bao

“…The resistance gene-related mobile genetic elements also share homologous sequences from different species or genera of bacteria. …”
Get full text

Revealing Genomic Profile That Underlies Tropism of Myeloma Cells Using Whole Exome Sequencing by Youngil Koh, Daeyoon Kim, Woo-June Jung, Kwang-Sung Ahn, Sung-Soo Yoon

“…Conclusion. We found out genetic changes that underlie tropism of myeloma cells using WES. …”
Get full text

Phenotypic and molecular characterization of the largest worldwide cluster of hereditary angioedema type 1. by Juan Sebastian Arias-Flórez, Sandra Ximena Ramirez, Bibiana Bayona-Gomez, Lina Castro-Castillo, Valeria Correa-Martinez, Yasmín Sanchez-Gomez, William Usaquén-Martínez, Lilian Andrea Casas-Vargas, Carlos Eduardo Olmos Olmos, Nora Contreras Bravo, Camilo Andres Velandia-Piedrahita, Adrien Morel, Rodrigo Cabrera-Perez, Natalia Santiago-Tovar, Cristian Camilo Gaviria-Sabogal, Ingrid Tatyana Bernal, Dora Janeth Fonseca-Mendoza, Carlos M Restrepo

“…Hereditary angioedema type 1 (HAE1) is a rare, genetically heterogeneous, and autosomal dominant disease. …”
Get full text

How to survive the mutational meltdown: lessons from plant RNA viruses by Lafforgue, Guillaume, Lefebvre, Marie, Michon, Thierry, Elena, Santiago F.

“…Such population expansions generate genetic diversity, serving as a buffer against, and potentially even leveraging, the effects of genetic drift.…”
Get full text

Advances in Nucleic Acid Drugs and Gene Therapies based on Animal Models of Duchenne Muscular Dystrophy by LIU Siyu, LAI Yuezhao, GUO Wenting, CHEN Xuejin

“…Duchenne muscular dystrophy (DMD) is a severe X-linked recessive genetic disorder caused by mutations in the DMD gene, making it one of the most common forms of hereditary muscular dystrophy. …”
Get full text

Screening Children with a Family History of Central Congenital Hypoventilation Syndrome by Hina Emanuel, Kimberly Rennie, Kelly Macdonald, Aravind Yadav, Ricardo A. Mosquera

“…Congenital central hypoventilation syndrome (CCHS) is a rare genetic disorder of an autonomic nervous disorder that affects breathing. …”
Get full text

Loeys-Dietz syndrome by Bogumiła Wójcik-Niklewska, Erita Filipek

“…Loeys-Dietz syndrome is a rare syndrome of genetically determined congenital defects characterized by specific dysmorphic features, vascular tortuosity, aneurysms, mitral valve disease, and bone abnormalities. …”
Get full text

GWSF-EuSWAP70 gene expression to enhance gray mold resistance in Arabidopsis thaliana by Zhenchi Huang, Xiaoming Li, Fenglian Cai, Lichun Li, Zhihua Wu

“…Traditional breeding methods are very time-consuming; therefore, plant genetic engineering has emerged as a promising approach for plant pathogen management. …”
Get full text

Research and development of intelligent bypass ring net cage and collaborative control technology of multi-source power supply system in flooded environment by Zhanhua Huang, Liang He

“…The improved non-dominated sorting genetic algorithm optimizes multi-source power supply systems. …”
Get full text

Extensive paralogism in the environmental pangenome: a key factor in the ecological success of natural SAR11 populations by Carmen Molina-Pardines, Jose M. Haro-Moreno, Francisco Rodriguez-Valera, Mario López-Pérez

“…Despite their abundance, challenges in recovering the full genetic diversity of natural populations have hindered our understanding of the eco-evolutionary mechanisms driving intra-species variation. …”
Get full text

Association of XRCC3, XRCC4, BAX, and BCL-2 Polymorphisms with the Risk of Breast Cancer by Emre Ozoran, Fadime Didem Can Trabulus, Duygu Erhan, Bahadir Batar, Mehmet Guven

“…Breast cancer is the most common malignancy in women. Genetic risk factors associated with breast cancer incidence have been identified. …”
Get full text

Epidemiological monitoring of avian influenza in the Republic of Crimea in 2019–2020 by D. V. Gadzevich, S. I. Danylchenko, N. V. Vorotilova, M. A. Pasunkina, V. A. Uppe, V. N. Irza, M. S. Volkov, N. G. Zinyakov

“…The comparative genetic analysis of 258 bp nucleic acid sequences of the AIV H gene fragment showed that the identified isolate belongs to the Asian genetic lineage of highly pathogenic AIV subtype H5 (clade 2.3.4.4) associated with the epidemic spread in Asia, Europe, the Middle East and Africa in 2016–2020.…”
Get full text

Differences and driving factors of leaf functional traits between old tree and mature tree of Pinus tabulaeformis in the Loess Plateau by Yuting Lei, Zimao Feng, Zhong Zhao

“…The difference was mainly driven by soil property and genetic factors (common explanation rate was 67.89%), and the independent effect of genetic factors (10.09%) was slightly higher than that of soil property factors (2.88%). …”
Get full text

Essential and recurrent roles for hairpin RNAs in silencing de novo sex chromosome conflict in Drosophila simulans. by Jeffrey Vedanayagam, Marion Herbette, Holly Mudgett, Ching-Jung Lin, Chun-Ming Lai, Caitlin McDonough-Goldstein, Stephen Dorus, Benjamin Loppin, Colin Meiklejohn, Raphaëlle Dubruille, Eric C Lai

“…Importantly, genetic interactions between nmy and tmy mutant alleles reveal that Tmy also specifically maintains male progeny for normal sex ratio. …”
Get full text

The Role of Dll4/Notch Signaling in Normal and Pathological Ocular Angiogenesis: Dll4 Controls Blood Vessel Sprouting and Vessel Remodeling in Normal and Pathological Conditions by Ivan Lobov, Natalia Mikhailova

“…Dll4 is a transmembrane protein that acts as a ligand for Notch receptors 1 and 4. Genetic deletion of Dll4 causes severe abnormalities in embryonic and postnatal vascular development. …”
Get full text