Reservoir of Bacterial Exotoxin Genes in the Environment by Veronica Casas, Joseph Magbanua, Gerico Sobrepeña, Scott T. Kelley, Stanley R. Maloy

“…Exotoxins are often encoded by mobile genetic elements, including bacteriophage (phage). …”
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Gene Carriers and Transfection Systems Used in the Recombination of Dendritic Cells for Effective Cancer Immunotherapy by Yu-Zhe Chen, Xing-Lei Yao, Yasuhiko Tabata, Shinsaku Nakagawa, Jian-Qing Gao

“…In several studies, DCs were genetically engineered by tumor-associated antigens or by immune molecules such as costimulatory molecules, cytokines, and chemokines. …”
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Kinematics Analysis and Simulation of Line-driven Hedge Trimming Manipulator by Xue Zan, Luo Tianhong, Chen Cai

“…The simulation results show that the genetic algorithm has high accuracy and fast solution. …”
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Cultivating crayfish (Procambarus clarkii) significantly enhances the quantity and diversity of soil microorganisms: evidence from the comparison of rice-wheat and rice-crayfish ro... by Hui Xu, Hui Xu, Dan Wang, Dan Wang, Dan Wang, Xuguang Li, Xuguang Li, Jiajia Li, Jiajia Li, Yu Xu, Yu Xu, Zhiqiang Xu, Zhiqiang Xu

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A c-type lectin HcLec1 with dual function of immunology and mineralization from the freshwater oyster (Hyriopsis cumingii Lea) by Xiaofeng Chen, Xiaoya Shen, Shijun Liu, Wenjuan Li, Wenjuan Li, He Wang, Jiale Li, Jiale Li, Zhiyi Bai, Zhiyi Bai

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Molecular mapping and validation of quantitative trait loci for content of micronutrients in wheat grain by Xiangdong Chen, Junchao You, Nannan Dong, Di Wu, Die Zhao, Rui Yong, Wenjing Hu

“…Manganese (Mn), iron (Fe), copper (Cu), zinc (Zn), and selenium (Se) are essential micronutrients for human health. However, the genetic basis for the content of Mn, Fe, Cu, Zn, and Se in wheat grains remains unclear. …”
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Diversity and seasonal variation of zooplankton community in a large deep-water reservoir of Eastern China using eDNA and morphological methods by Lei Hao, Lei Hao, Xinting Xu, Xinting Xu, Yan Zhou, Yan Zhou, Dan Liu, Dan Liu, Jianqiang Shao, Jiayong Pan, Guangxi He, Zhongjun Hu, Zhongjun Hu, Qigen Liu, Qigen Liu

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Gene Therapy Approaches by Ahmed Jumaa Ahmed, Hogir Saadi

“… Gene therapy can be described broadly as the transfer of genetic material to control a disease or at least to enhance a patient's clinical status. …”
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Genomic and phenotypic selection indices for decreased birth weight, shortening fattening period, and regulating total weight gain in beef cattle by Kenji Togashi, Atsushi Ogino, Toshio Watanabe, Masakazu Shinomiya, Masashi Kinukawa, Kazuhito Kurogi, Masanobu Nurimoto

“…Thus, we expect that these indices will contribute to sustainable genetic improvement in cattle while maintaining genetic diversity.…”
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Control of Magnetic Manipulator Using Reinforcement Learning Based on Incrementally Adapted Local Linear Models by Martin Brablc, Jan Žegklitz, Robert Grepl, Robert Babuška

“…We benchmark two state-of-the-art methods, SNGP (single-node genetic programming) and MGGP (multigene genetic programming), against a standard incremental local regression method called RFWR (receptive field weighted regression). …”
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Inhibition of Viability, Proliferation, Cytokines Secretion, Surface Antigen Expression, and Adipogenic and Osteogenic Differentiation of Adipose-Derived Stem Cells by Seven-Day Ex... by Jian Wang, Bo Xiang, Jixian Deng, Darren H. Freed, Rakesh C. Arora, Ganghong Tian

“…Exposure to 0.5 T SMF for seven days inhibited viability, proliferation, surface antigen expression, cytokine secretion, stem cell genetic marker expression, and adipogenic and osteogenic differentiation but did not affect the DNA integrity in ASCs with or without SPIO labeling.…”
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Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis by Alexandra Noble, Rodrigo Motta, Silvia Cabras, Belen Moron Flores, Jan Nowak, Aleksandra Glapa-Nowak, Alessandra Geremia, Jack Satsangi, Emma Culver

“…Abstract Background IgG4-related cholangitis (IgG4-SC) and primary sclerosing cholangitis (PSC) are chronic fibro-inflammatory hepatobiliary conditions, with genetic, environmental, and immunologic risk factors, in which epigenetic alterations may provide insights into pathophysiology and novel biomarkers. …”
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Emergence of invasive Streptococcus dysgalactiae subsp. equisimilis in Spain (2012-2022): genomic insights and clinical correlations by Guillem López de Egea, Aida González-Díaz, Randall J Olsen, Gérard Guédon, Dàmaris Berbel, Immaculada Grau, Jordi Càmara, Lucía Saiz-Escobedo, Sara Calvo-Silveria, Irene Cadenas-Jiménez, José María Marimón, Emilia Cercenado, Antonio Casabella, Sara Martí, M. Ángeles Domínguez, Nathalie Leblond-Bourget, James M Musser, Carmen Ardanuy

“…Whole genome sequencing revealed a high genetic diversity, with the most common lineages being CC15, CC17, and CC20. …”
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A Y-chromosome portrait of the population of Jerba (Tunisia) to elucidate its complex demographic history by Franz Manni, Pascal Leonardi, Étienne Patin, Alain Berrebi, Houssein Khodjet el Khil, Karl Skorecki, Dror Rosengarten, Hassan Rouba, Evelyne Heyer, Marc Fellous

“…We also sampled the Black group living in Jerba but typing ambiguities forced us to exclude it from further analyses.The results suggest a very low degree of genetic differentiation between Jerban Arabs and Berbers, who can be considered genetically, as belonging to the same group. …”
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Family Aggregation and Risk Factors for Breast Cancer in Affected Individuals by Julio Armando Sánchez Delgado, Nailé Edita Sánchez Lara

“…<strong><br />Conclusions:</strong> confluence of genetic and environmental factors determines family aggregation of breast cancer.…”
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Lysine deacetylase inhibitors have low selectivity in cells and exhibit predominantly off‐target effects by Kiara E. Bornes, Marcus A. Moody, Thomas M. Huckaba, Megan C. Benz, Emily C. McConnell, Maryam Foroozesh, Van H. Barnes, Bridgette M. Collins‐Burow, Matthew E. Burow, Terry J. Watt, Tasha B. Toro

“…Developing a truly specific KDAC6 inhibitor could be a promising therapeutic avenue, but it is imperative to develop new inhibitors that selectively mimic genetic inactivation of individual KDACs.…”
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Mutational Analysis of a Familial Adenomatous Polyposis Pedigree with Bile Duct Polyp Phenotype by Li-jun Xie, Dan-dan Ruan, Jian-hui Zhang, Yi Li, Li Chen, Mao-lin Yan, Ming-dian Yu, Jie-wei Luo, Hui-zhen Zhang

“…Familial adenomatous polyposis (FAP) is an autosomal dominant genetic disease caused by mutations in the adenomatous polyposis coli (APC) gene. …”
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Field apple scab susceptibility of a diverse Malus germplasm collection identifies potential sources of resistance for apple breeding by David Papp, Liqiang Gao, Ranjita Thapa, Dan Olmstead, Awais Khan

“…Abstract Background Breeding for resistance to apple scab (caused by Venturia inaequalis), the most devastating fungal disease of apples, relies on genetic resources maintained in germplasm collections. …”
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The clinical value and most informative threshold of polygenic risk score in the Quebec City Case-Control Asthma Cohort by Martin Pariès, Stéphanie Bougeard, Aida Eslami, Zhonglin Li, Michel Laviolette, Louis-Philippe Boulet, Evelyne Vigneau, Yohan Bossé

“…Abstract Genome-wide association studies (GWAS) have identified genetic variants robustly associated with asthma. …”
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Hemophilia A Haplotypes in Southwestern Iran by Bizhen Keikhaei Dehdezi, Ali Khodadadi, Arta Farhadi Kia, Faezeh Abbasi, Saeed Bitraf, Roya Salehi Kahyesh

“…Genetic testing is also indicated for carrier identification and prenatal diagnosis.…”
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