Chromosome 1 Sequence Analysis of C57BL/6J-Chr1KM Mouse Strain by Fuyi Xu, Tianzhu Chao, Yiyin Zhang, Shixian Hu, Yuxun Zhou, Hongyan Xu, Junhua Xiao, Kai Li

“…In conclusion, our analysis provided a detailed description of the genetic variations on Chr 1 of B6-Chr1KM and a new perspective on the subspecies origin of KM mouse which can be used to guide further genetic studies with this mouse strain.…”
Get full text

Population features of prevalence and clinical-diagnostic role of NOD2 gene polymorphisms associated with Crohn’s disease by D. A. Kuznetsova, M. V. Merzlyakov, G. V. Vavin, A. S. Razumov, V. L. Emanue

“…According to literature data analysis it is possible to conclude that there are clear populationrelated features of the prevalence, clinical and diagnostic role of NOD2 genetic polymorphism associated to Crohn's disease that requires development of the international data bank of all genetic nucleotide polymorphisms associated to various stages of CD pathogenesis in different countries and populations. …”
Get full text

CompàreGenome: a command-line tool for genomic diversity estimation in prokaryotes and eukaryotes by Gabriele Moro, Rossano Atzeni, Ali Al-Subhi, Maria Giovanna Marche

“…The tool also distinguished organisms at the strain level and quantified genetic distances using three distinct analytical methods. …”
Get full text

Production scheduling with multi-robot task allocation in a real industry 4.0 setting by Zohreh Shakeri, Khaled Benfriha, Mohsen Varmazyar, Esma Talhi, Anthony Quenehen

“…Based on the data, the Proposed Genetic Algorithm (PGA), with an average Relative Deviation (ARD) of 0.25%, performed approximately 34% better compared to the Basic Genetic Algorithm (BGA), with an average ARD of 0.38%. …”
Get full text

Hyperthermia suppresses the biological characteristics and migration of chicken primordial germ cells by Yuzhou Gu, Yuzhou Gu, Yuzhou Gu, Kexin Wu, Kexin Wu, Kexin Wu, Bowen Niu, Bowen Niu, Bowen Niu, Zhiting Wang, Zhiting Wang, Zhiting Wang, Yuchen Jie, Yuchen Jie, Yuchen Jie, Zixuan Fan, Zixuan Fan, Zixuan Fan, Junying Li, Junying Li, Congjiao Sun, Congjiao Sun, Congjiao Sun, Zhuo-Cheng Hou, Zhuo-Cheng Hou, Zhuo-Cheng Hou, Li-Wa Shao, Li-Wa Shao, Li-Wa Shao

“…Primordial germ cells (PGCs) play a crucial role in transmitting genetic information to the next-generation. In chickens, genetically edited PGCs can be propagated in vitro and subsequently transplanted into recipient embryos to produce offspring with desired genetic traits. …”
Get full text

Myocardial Infarction and AGT p.Thr174Met Polymorphism: A Meta-Analysis of 7657 Subjects by Yan-yan Li, Hui Wang, Hao Wang, Yang-yang Zhang

“…No significant association between AGT p.Thr174Met polymorphism and MI was found under all genetic models in the Caucasian subgroup (P>0.05). …”
Get full text

Halothermophilic Cas9 and dCas9 Interaction with Variety sgRNA In-silico by Kenny Lischer, Kholisoh Hayati, Muhammad Haykal Fabian, Fina Amreta Laksmi, Yudhi Nugraha, Hamdan Dwi Rizqi, Riri Fauziyya, Sarmoko, Mohd Shukuri Mohamad Ali

“…Enhancing production yield is important, and one approach genetic modification. Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a highly effective method for genetic editing; however, its use in halothermophilic bacteria remains limited. …”
Get full text

Case report: Novel multi-exon homozygous deletion of ZBTB24 causes immunodeficiency, centromeric instability, and facial anomalies syndrome 2 by Yan Long, Chenghan Wang, Jie Xiao, Yunhua Huang, Xiaoting Ling, Chaoyu Huang, Ying Chen, Jiaqi Luo, Rongheng Tang, Faquan Lin, Yifang Huang

“…This study aimed to investigate the phenotype and immune function of a girl with ICF2, identify her genetic defect, and explore the potential pathogenic mechanisms of the disease. …”
Get full text

Maternal and Child Program’s behavior of some indicators in a family medical office. Cienfuegos, 2013-2022 by Mileidy Portal Amador, Alina Esther González Hermida, Hildeli Suárez López, Iranidel Rodríguez Padrón

“…Genetic alterations were not frequent (0.6%). 94% of the children who received exclusive breastfeeding had hemoglobin levels greater than or equal to 110g/l. …”
Get full text

Investigating Rice Blast Resistance Gene Distribution among Landrace Rice Varieties in Lower Northern Thailand for Improving Rice Cultivars by Sittichai Urtgam, Kawee Sujipuli, Urasri Suyasunanont, Nontaporn Rattanachak, Jirapas Jongjitwimol, Touchkanin Jongjitvimol

“…This finding provided the genetic information and diversity of the R genes across landrace rice varieties in the lower north of Thailand. …”
Get full text

Identification of HNF4A Mutation p.T130I and HNF1A Mutations p.I27L and p.S487N in a Han Chinese Family with Early-Onset Maternally Inherited Type 2 Diabetes by Ying Yang, Tai-Cheng Zhou, Yong-Ying Liu, Xiao Li, Wen-Xue Wang, David M. Irwin, Ya-Ping Zhang

“…Maturity-onset diabetes of the young (MODY) is characterized by the onset of diabetes before the age of 25 years, positive family history, high genetic predisposition, monogenic mutations, and an autosomal dominant mode of inheritance. …”
Get full text

Scent of COVID-19: Whole-Genome Sequencing Analysis Reveals the Role of <i>ACE2</i>, <i>IFI44</i>, and <i>NDUFAF4</i> in Long-Lasting Olfactory Dysfunction by Beatrice Spedicati, Alessandro Pecori, Maria Pina Concas, Aurora Santin, Romina Ruberto, Giuseppe Giovanni Nardone, Andrea D’Alessandro, Giancarlo Tirelli, Paolo Boscolo-Rizzo, Giorgia Girotto

“…COVID-19-related persistent olfactory dysfunction (OD) presents remarkable interindividual differences, and little is known about the host genetic factors that are involved in its etiopathogenesis. …”
Get full text

Prediction of Chaotic Time Series Based on BEN-AGA Model by LiYun Su, Fan Yang

“…Aiming at the prediction problem of chaotic time series, this paper proposes a brain emotional network combined with an adaptive genetic algorithm (BEN-AGA) model to predict chaotic time series. …”
Get full text

Mitochondrial DNA barcoding of mosquito species (Diptera: Culicidae) in Thailand. by Tanawat Chaiphongpachara, Tanasak Changbunjong, Sedthapong Laojun, Teerayoot Nutepsu, Nantana Suwandittakul, Kewarin Kuntawong, Suchada Sumruayphol, Jiraporn Ruangsittichai

“…The average maximum intraspecific genetic variation of the 73 mosquito species was 1% ranged from 0-5.7%. …”
Get full text

CDK14 regulates the development and repair of lung by Jian-wei Chen, Yu-xiang Wang, Rong-rong Gao, Lan-yue Ma, Jing Zhong, Jia-xin Yang, Zhao-hua Deng, Yu-yan Li, Xiao-ling Li, Ya-hai Shu, Wen-jing Guo, Zi-yuan Zhou, Xiao Yu Tian, Jinjin Ma, Yang Liu, Qi Chen

“…However, the function of CDK14 during organ development and regeneration has not been investigated in genetically-modified animals. Here, we found that genetic ablation of Cdk14 influenced pulmonary vascular endothelial cells and alveolar epithelial cells during mice embryonic development as well as repair of lung after bleomycin or lipopolysaccharide induced injury. …”
Get full text

Assessing in-vitro models for microglial development and fetal programming: a critical review by Steven Schepanski, Steven Schepanski, Gonza B. Ngoumou, Gonza B. Ngoumou, Claudia Buss, Claudia Buss, Claudia Buss, Claudia Buss, Georg Seifert, Georg Seifert

“…Key factors such as scalability, genetic and epigenetic fidelity, and physiological relevance are highlighted. …”
Get full text

Chromosomal abnormalities in children as a predictor of the development of congenital heart and vascular diseases by Z.V. Selska, O.R. Sadova, V.I. Bobrova, K.E. Popov

“…The importance of studying chromosomal pathology in the context of CHD lies in the possibility of identifying specific genetic markers that are predictors of the development of these conditions. …”
Get full text

An Integrating Approach for Genome-Wide Screening of MicroRNA Polymorphisms Mediated Drug Response Alterations by Xianyue Wang, Hong Jiang, Wei Wu, Rongxin Zhang, Lingxiang Wu, Huan Chen, Pengping Li, Yumin Nie, Jiaofang Shao, Yan Li, Xue Lin, Sali Lv, Qh Wang, Jie Hu

“…However, there are still a large number of specific genetic variants related to drug efficiency that are yet to be discovered. …”
Get full text

Assessment of cardiac iron deposition and genotypic classification in pediatric beta-thalassemia major: the role of cardiac MRI by Siqi Zhang, Wen Zhao, Longwei Sun, Guohua Liang, Xiaodong Wang, Hongwu Zeng

“…Abstract Background Beta thalassemia major (β-TM) is a severe genetic anemia with considerable phenotypic heterogeneity. …”
Get full text

Ecological drivers of evolution of swine influenza in the United States: a review by Varun Goel, Jessica Ding, Bijaya Hatuwal, Emily Giri, Thomas J. Deliberto, James Lowe, Richard Webby, Michael Emch, Xiu-Feng Wan

“…In the United States, IAVs are enzootic in commercial swine farming operations, with numerous genetic and antigenic IAV variants having emerged in the past two decades. …”
Get full text