Ensuring patient access to gene therapies for rare diseases: Navigating reimbursement and coverage challenges by Diane Berry, Carolyn Hickey, Lisa Kahlman, James Long, Christina Markus, Caitlin K. McCombs

“…The rapid transformation in rare disease treatment, driven by advances in genetic medicine and diagnostics, underscores the urgent need for access to these innovative therapies. …”
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The Promise of Human Induced Pluripotent Stem Cells in Dental Research by Thekkeparambil Chandrabose Srijaya, Padmaja Jayaprasad Pradeep, Rosnah Binti Zain, Sabri Musa, Noor Hayaty Abu Kasim, Vijayendran Govindasamy

“…Induced pluripotent stem cell-based therapy for treating genetic disorders has become an interesting field of research in recent years. …”
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PTCH1 mutations' role in keratocystic odontogenic tumors and nevoid basal cell carcinoma syndrome by Archana Behera, Mukesh Kumar Dharmalingam Jothinathan

“…This underscores the importance of targeted therapies, specifically in instances of resistance, and the tailoring of treatment plans under genetic knowledge.…”
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Advances in Murine Models of Diabetic Nephropathy by Li-li Kong, Hao Wu, Wen-peng Cui, Wen-hua Zhou, Ping Luo, Jing Sun, Hang Yuan, Li-ning Miao

“…Here we review the identified murine models of DN from the aspects of genetic background, type of diabetes, method of induction, gene deficiency, animal age and gender, kidney histopathology, and phenotypic alterations in the hope of enhancing our comprehension of genetic susceptibility and molecular mechanisms responsible for this disease and providing new clues as to how to choose appropriate animal models of DN.…”
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Repeated Successful Nest Sharing and Cooperation Between Western Kingbirds (Tyrannus verticalis) and a Female Western Kingbird × Scissor‐Tailed Flycatcher (T. forficatus) Hybrid... by Alexander J. Worm, Emily R. Donahue, Than J. Boves, Andrew D. Sweet

“…ABSTRACT Nest sharing by birds, or the phenomenon where multiple individuals of different species contribute genetically and parentally to offspring in a single nest, is a rare form of cooperative breeding that has only occasionally been reported in socially monogamous birds. …”
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Influence of the Soil Genesis on Physical and Mechanical Properties by Marian Marschalko, Işık Yilmaz, Lucie Fojtová, Karel Kubečka, Tomáš Bouchal, Martin Bednárik

“…The soils of the fluvial origin manifest different values than other genetic types. Next, based on regression analyses, dependence was proved neither on the deposition depth (depth of samples) nor from the point of view of the individual foundation soil classes or the genetic types. …”
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THE ROLE OF THE VAVILOV INSTITUTE OF PLANT INDUSTRY IN THE INITIATION AND DEVELOPMENT OF NEW TRENDS IN WINTER RYE BREEDING IN RUSSIA by V. D. Kobyliansky, O. V. Solodukhina

“…Scientific investigations conducted at VIR during 1960-2014 to identify sources of new promising and economically useful traits in rye resulted in the development of genetic donors of such traits capable of increasing breeders’ work efficiency. …”
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Morphological Diversity among Accessions of Apple Tree (Malus × Domestica Borkh) by Simon Mada Mbovora, Cousin Musvosvi, Edmore Gasura

“…A narrow genetic diversity was observed as reflected by the pairwise genetic similarity matrix that ranged from 80 to 100%. …”
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Behavior of Olive Genotypes Against Quick Decline Syndrome (QDS) Caused by <i>Xylella fastidiosa</i> subsp. <i>pauca</i> in Apulia by Mariangela Carlucci, Michele Antonio Savoia, Pompea Gabriella Lucchese, Valentina Fanelli, Isabella Mascio, Francesco Luigi Aurelio, Monica Marilena Miazzi, Andrea Pacifico, Cinzia Montemurro, Franco Nigro

“…This study integrates phenotypic responses with genetic knowledge to support the development of conservation strategies that will enhance the genetic diversity of Apulian olive cultivars. …”
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Social technology and rescue of native seeds in the Venezuelan Andes Páramo by Iraima Lugo Montilla, Carla Ladeira Pimentel Águas

“…These initiatives counter historical trends, such as the erosion of complex genetic resource systems, genetic resources, the impacts of agricultural modernization, dependency on oil and imported agricultural technologies, and more recent challenges, such as food shortages. …”
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Fetal and neonatal cardiac tumor diagnosed as Tuberous Sclerosis associated rhabdomyomas resulting from novel pathogenic missense variant detected in TSC2 gene: A case report by Aya Kawasaki, MD, Hidefumi Tonoki, MD, PhD, Osamu Sasaki, MD, PhD, Yoko Matsushita, MD, PhD, Michiko Watari, MD, PhD, Nobuhiro Takahashi, MD, Satoko Fujieda, MD

“…Once the parents were provided careful genetic counseling, a genetic analysis for TS was performed when the patient was 2 years old that demonstrated a novel pathogenic missense variant: c.1072T>C, p.Trp358Arg in the TSC2 gene with 30% mosaicism. …”
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Is Vitamin D Deficiency the Cause or the Effect of Systemic Lupus Erythematosus: Evidence from Bidirectional Mendelian Randomization Analysis by Yang Ding, Shengyi Yang, Shasha Fan, Yi Tang, Yan Teng, Xiaohua Tao, Wei Lu

“…In this bidirectional Mendelian randomization (MR) study, we explored the genetic association between serum vitamin D (VD) levels and SLE using two models. …”
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Phylogenetic analysis and the spatial spread of arctic rabies virus in Chukotka by Sergey A. Chupin, Aleksandr D. Botvinkin, Ivan D. Zarva, Elena V. Chernyshova

“…For over 15 years the genetic diversity of the RABV in the Arctic has been the subject of intensive research. …”
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Genome-wide association studies in lettuce reveal the interplay of seed age, color, and germination under high temperatures by Sookyung Oh, Ezekiel Ahn, Ainong Shi, Beiquan Mou, Sunchung Park

“…While beneficial for wild plants, thermoinhibition can adversely affect crop yields due to uneven and reduced germination rates, particularly in the face of climate change. To understand the genetic basis of thermoinhibition, we conducted a comprehensive genetic analysis of a diverse panel of Lactuca spp. accessions. …”
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A first-born twin has a higher risk of acute leukemia in a population-based assessment of cancer in twins in California, and a lower than anticipated rate of twin concordance by Eric M. Nickels, Naying Zhou, Joseph L. Wiemels

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Genome-wide linkage mapping of Fusarium crown rot in common wheat (Triticum aestivum L.) by Faji Li, Can Guo, Qi Zhao, Weie Wen, Shengnan Zhai, Xinyou Cao, Cheng Liu, Dungong Cheng, Jun Guo, Yan Zi, Aifeng Liu, Jianmin Song, Jianjun Liu, Jindong Liu, Haosheng Li

“…Furthermore, we developed and validated two kompetitive allele-specific PCR (KASP) markers, Kasp_3AL_FCR (QFCR.caas-3AL) and Kasp_5BL_FCR (QFCR.caas-5BL), in a natural population of 202 wheat varieties.DiscussionThis study contributes new genetic insights and provides new stable loci and available KASP markers for breeding to enhance FCR resistance in common wheat.…”
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Novel Compound Heterozygous PRKN Variants in a Han-Chinese Family with Early-Onset Parkinson’s Disease by Kuan Fan, Pengzhi Hu, Chengyuan Song, Xiong Deng, Jie Wen, Yiming Liu, Hao Deng

“…Genetic factors are thought to play an important role in the pathogenesis of Parkinson’s disease (PD), particularly early-onset PD. …”
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Optimal Scheduling for Retrieval Jobs in Double-Deep AS/RS by Evolutionary Algorithms by Kuo-Yang Wu, Sendren Sheng-Dong Xu, Tzong-Chen Wu

“…Three types of evolutionary algorithms, the Genetic Algorithm (GA), the Immune Genetic Algorithm (IGA), and the Particle Swarm Optimization (PSO) algorithm, are implemented to obtain the optimal assignments. …”
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Novel frameshift variant of WNT10A in a Japanese patient with hypodontia by Michiyo Ando, Yoshihiko Aoki, Yasuto Sano, Junya Adachi, Masatoshi Sana, Satoru Miyabe, Satoshi Watanabe, Shogo Hasegawa, Hitoshi Miyachi, Junichiro Machida, Mitsuo Goto, Yoshihito Tokita

“…Here, we investigated the genetic causes of sporadic congenital tooth agenesis. …”
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Qualitative and quantitative characteristics of black patch trait in Oujiang color common carp by Ke Jing, Huifan Chen, Nusrat Hasan Kanika, Penghui Zhang, Roland Nathan Mandal, Chunxiao Zeng, Zhiyi Zhang, Jun Wang, Chenghui Wang

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