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6381
The perspectives of metabolomics studies of potato plants
Published 2017-03-01“…Metabolome profiling is widely employed to study differences between genetically modified forms of potatoes from untransformed relatives. …”
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Transcription factor KLF2 is associated with the dysfunctional status of NK cells and the prognosis of pediatric B-ALL patients
Published 2025-01-01“…However, NK cells fail to restrain the growth of malignancies, such as B-cell acute lymphoblastic leukemia (B-ALL). The molecular genetics of NK cells in the B-ALL bone marrow microenvironment and the mechanisms underlying the inhibited function of NK cells at the single-cell level remain largely elusive.MethodsIn this study, we studied the frequency and absolute number of NK cells in peripheral blood samples collected from 43 healthy volunteers and 104 pediatric B-ALL patients diagnosed at Hunan Children’s Hospital. …”
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Assessment of relationships between epigenetic age acceleration and multiple sclerosis: a bidirectional mendelian randomization study
Published 2025-01-01“…Methods This analysis employed statistics approaches from genome-wide association studies related to various epigenetic clocks (GrimAge, HannumAge, PhenoAge, and HorvathAge) and multiple sclerosis, utilizing robust instrumental variables from the Edinburgh DataShare (n = 34,710) and the International Multiple Sclerosis Genetics Consortium (including 24,091 controls and 14,498 cases). …”
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6388
Factors to affect inbred beet plants while developing material for linear selection
Published 2019-07-01Get full text
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6390
The volatilome – investigation of volatile organic metabolites (VOM) as potential tumor markers in patients with head and neck squamous cell carcinoma (HNSCC)
Published 2018-07-01“…These volatile organic metabolites (VOM) represent a kind of biosignature that reflects the sum of all multifactorial influences, including genetics, environmental factors, nutritional and disease status. …”
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6391
Technical considerations towards commercialization of porcine respiratory and reproductive syndrome (PRRS) virus resistant pigs
Published 2022-06-01“…Rather than backcrossing the resistance gene from a few non-commercial founders, as a global supplier of high genetic merit livestock genetics, Genus plc and its pig division PIC (Pig Improvement Company) with Genus R&D have mobilized advances in reproductive biology, gene editing, DNA sequencing, and bioinformatics to simultaneously generate and introduce a single modified CD163 allele across four genetically diverse porcine lines of commercial importance that prevents PRRS virus (PRRSV) infection. …”
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6392
Chromosome‐scale genome assembly of Poa trivialis and population genomics reveal widespread gene flow in a cool‐season grass seed production system
Published 2024-03-01“…A reduced‐representation sequencing analysis of field populations revealed limited genetic diversity and suggested potential gene flow and human‐assisted dispersal in the region. …”
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Stress resistance in barley cultivars of various agroecological origin under extreme continental climate conditions
Published 2020-12-01“…Vavilov AllRussian Institute of Plant Genetic Resources (VIR), being the main source of source material for breeding, is insufficiently studied under conditions of extreme continental climate. …”
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Genome-wide association study for charcoal rot resistance in soybean harvested in Kazakhstan
Published 2023-11-01“…Merrill.) worldwide. Identifying the genetic factors associated with resistance to charcoal rot is crucial for developing disease-resistant soybean cultivars. …”
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6396
MINERAL COMPOSITION OF WILD RELATIVES AND INTROGRESSIVE FORMS IN WHEAT SELECTION
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6397
The Role of Macrophages in the Pathogenesis of Celiac Disease
Published 2024-10-01“…Celiac disease is an autoimmune disease with a characteristic serological (antibodies to tissue transglutaminase, endomysium, deamidated gliadin peptides) and histological profile (inflammatory infiltration of the villous epithelium by lymphocytes and their atrophy, crypt hyperplasia) caused by gluten consumption in genetically predisposed individuals. Macrophages, as key cells that provide a link between innate and adaptive immunity, are of significant importance in the pathogenesis of celiac disease. …”
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Prediction of some peroxidase functions in <i>Arabidopsis thaliana</i> L. by bioinformatic search
Published 2019-08-01Get full text
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Identification of QTLs for resistance to leaf and stem rusts in bread wheat (Triticum aestivum L.) using a mapping population of ‘Pamyati Azieva × Paragon’
Published 2019-11-01“…The study is an initial step of the genetic mapping of LR and SR resistance loci of bread wheat in Kazakhstan. …”
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