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5521
Molecular detection and genomic characterization of Samak Micromys paramyxovirus-1 and -2 in Micromys minutus, Republic of Korea
Published 2024-10-01“…The discovery of SMPV-1 and SMPV − 2 also reveals the genetic diversity and evolutionary history of the genus Jeilongvirus in the Paramyxoviridae.…”
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Generation of INS-jGCaMP7f knock-in Ca2+ reporter human embryonic stem cell line, GZLe001-C, using CRISPR/Cas9-based gene targeting
Published 2025-02-01“…As a member of the single-fluorophore genetically encoded calcium indicators (GECIs), jGCaMP7f is widely applied to investigate intracellular Ca2+ concentrations. …”
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5527
Development of a Human Intestinal Organoid Model for In Vitro Studies on Gut Inflammation and Fibrosis
Published 2021-01-01Get full text
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5529
Molecular genotyping revealed the gene flow of Puccinia striiformis f. sp. tritici clonal lineage from Uzbekistan of Central Asia to Xinjiang of China
Published 2025-01-01“…The migration of clonal lineage could cause genetic drift and potential threat changing the genetic structure and virulence pattern of Pst in China. …”
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Caution when using network partners for target identification in drug discovery
Published 2025-04-01“…However, recent data indicate that leveraging human genetic evidence to identify and validate these targets significantly increases the likelihood of success in drug development. …”
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A conceptual model and practical guidance for the development, administration, and evaluation of individualized therapies
Published 2025-01-01“…Bespoke therapies represent a promising tool to address a diverse range of genetic and acquired conditions, offering new hope where conventional treatments have fallen short. …”
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Functional genomics implicates ebony in the black pupae phenotype of tephritid fruit flies
Published 2025-01-01“…Abstract The remarkable diversity of insect pigmentation offers a captivating avenue for studying evolution and genetics. In tephritids, understanding the molecular basis of mutant traits is also crucial for applied entomology, enabling the creation of genetic sexing strains through genome editing, thus facilitating sex-sorting before sterile insect releases. …”
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5535
Impact of pubertal timing on growth progression and final height in subjects affected by RASopathies
Published 2025-01-01Get full text
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Differentiation of <i>Bos grunniens</i> and <i>Bos taurus</i> based on STR locus polymorphism
Published 2023-09-01“…Differentiation of closely related biological species using molecular genetic analysis is important for breeding farm animals, creating hybrid lines, maintaining the genetic purity of breeds, lines and layering. …”
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Modeling of auditory neuropathy spectrum disorders associated with the TEME43 variant reveals impaired gap junction function of iPSC-derived glia-like support cells
Published 2025-01-01“…Its etiology is complex and can be broadly categorized into genetic and non-genetic factors. TMEM43 mutation is identified as a causative factor in ANSD. …”
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Study of Protein Biomarkers of Diabetes Mellitus Type 2 and Therapy with Vitamin B1
Published 2015-01-01Get full text
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