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5181
Identification of p53 and Its Isoforms in Human Breast Carcinoma Cells
Published 2014-01-01“…In breast carcinoma, disruption of the p53 pathway is one of the most common genetic alterations. The observation that the p53 can express multiple protein isoforms adds a novel level of complexity to the outcome of p53 mutations. p53 expression was analysed by Western immunoblotting and immunohistochemistry using monoclonal antibodies DO-7, Pab240, and polyclonal antiserum CM-1. …”
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5182
The Anti-proliferative Effect of a Novel Glutaminase Inhibitor IN-3 on Prostate Cancer Cells
Published 2024-09-01Get full text
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5183
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5184
Effects of limited introgressions from Triticum timopheevii Tausch. into the genome of bread wheat (Triticum aestivum L.) on physiological and biochemical traits under normal water...
Published 2015-12-01“…Thus, it may be supposed that 2A, 2B and 5A chromosomes of the drought-tolerant cultivar S29 carry important genetic factors responsible for reaction to water stress in wheat plants.…”
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5185
Molecular and Clinical Overview of Type 1 Neurofibromatosis: Single Center Study and Mini Review on NF1-Associated Vasculopathy and Juvenile Myelomonocytic Leukemia
Published 2024-10-01“…Objective: Neurofibromatosis type 1 (NF1) is a genetic disorder presenting primary with variable patterns of skin pigmentation, neurofibromas and iris Lisch nodules. …”
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5186
Detection of CRISPR cassettes and cas genes in the Arabidopsis thaliana genome
Published 2019-11-01“…The state of the art in the evolution of plant viruses allows the genetic foundations of antiviral immunity in higher (including the most important crops) plants to be categorized as one of the most pressing issues of genetics and selection. …”
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5187
Computer modeling of the peculiarities in the interaction of IL-1 with its receptors in schizophrenia
Published 2024-05-01“…One of the primary theories regarding the development of schizophrenia revolves around genetics, indicating the involvement of hereditary factors in various processes, including inflammation. …”
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5188
Human-based complex in vitro models: their promise and potential for rare disease therapeutics
Published 2025-01-01“…More than 70% of rare diseases are genetic in nature, with patient-specific mutations. …”
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5189
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5190
Whole-Exome Sequencing Identifies One De Novo Variant in the FGD6 Gene in a Thai Family with Autism Spectrum Disorder
Published 2018-01-01“…Autism spectrum disorder (ASD) has a strong genetic basis, although the genetics of autism is complex and it is unclear. …”
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5191
Microdifferential Pressure Measurement Device for Cellular Microenvironments
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5192
On three cultivated subspecies of pea (Pisum sativum L.)
Published 2017-11-01“…Two subspecies of the common pea, traditionally recognised in Russian botanical and genetical literature, Pisum sativum L. subsp. transcaucasicum Makasheva from Transcaucasia and Pisum sativum L. subsp. asiaticum Govorov from Anterior and Central Asia and North Africa, are considered, as well as their diagnostic characters and arguments in favour of their subspecific status. …”
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5193
Technological properties of grain and flour in bread wheat (<i>Triticum aestivum</i> L.) genotypes carrying two loci that determine the endosperm structure
Published 2021-04-01“…For the first time, a set of supersoft-grain lines with special properties of grain and flour was obtained on the genetic basis of three spring cultivars. They may be in demand for a wide range of end-uses, including both food and nonfood production purposes.…”
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5194
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5195
Preliminary Results of the Kuznetsk Coal Basin Cover Deposits Radon Hazard Assessment
Published 2025-01-01Get full text
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5196
A method for siRNA-mediated knockdown of target genes in RA-induced neurogenesis using P19 cells
Published 2025-06-01Get full text
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5197
The genomic pattern of insertion/deletion variations during rice improvement
Published 2024-12-01“…These results will provide valuable genetic and material resources for the genetic improvement of rice.…”
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5198
Six events that shaped antibody approvals in oncology
Published 2025-02-01“…Finally, we explore the development of ipilimumab, the first immune checkpoint-inhibiting antibody that activates the immune system to kill cancer cells, and the discovery that allowed the use of checkpoint inhibitors across all cancer types based on the presence of genetic markers. Revisiting these key events provides critical insights into the process of antibody development in oncology.…”
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5199
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5200
Tissue-specific effects of benzo[a]pyrene and DDT on microRNA expression profile in female rats
Published 2018-04-01Get full text
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