Human-based complex in vitro models: their promise and potential for rare disease therapeutics by Surat Parvatam, Francesca Pistollato, Lindsay J. Marshall, Fabia Furtmann, Devashree Jahagirdar, Mohua Chakraborty Choudhury, Sujata Mohanty, Harshita Mittal, Saveetha Meganathan, Rakesh Mishra

“…More than 70% of rare diseases are genetic in nature, with patient-specific mutations. …”
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Study of nodulation and nitrogen fixation in two cowpea [Vigna unguiculata (L.) Walp.] cultivars inoculated with different strains of Bradyrhizobium sp. by Yu. V. Fotev, K. K. Sidorova, T. I. Novikova, V. P. Belousova

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Whole-Exome Sequencing Identifies One De Novo Variant in the FGD6 Gene in a Thai Family with Autism Spectrum Disorder by Chuphong Thongnak, Areerat Hnoonual, Duangkamol Tangviriyapaiboon, Suchaya Silvilairat, Apichaya Puangpetch, Ekawat Pasomsub, Wasun Chantratita, Pornprot Limprasert, Chonlaphat Sukasem

“…Autism spectrum disorder (ASD) has a strong genetic basis, although the genetics of autism is complex and it is unclear. …”
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Microdifferential Pressure Measurement Device for Cellular Microenvironments by Mami Akaike, Jun Hatakeyama, Yoichi Saito, Yoshitaka Nakanishi, Kenji Shimamura, Yuta Nakashima

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On three cultivated subspecies of pea (Pisum sativum L.) by O. E. Kosterin

“…Two subspecies of the common pea, traditionally recognised in Russian botanical and genetical literature, Pisum sativum L. subsp. transcaucasicum Makasheva from Transcaucasia and Pisum sativum L. subsp. asiaticum Govorov from Anterior and Central Asia and North Africa, are considered, as well as their diagnostic characters and arguments in favour of their subspecific status. …”
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Technological properties of grain and flour in bread wheat (<i>Triticum aestivum</i> L.) genotypes carrying two loci that determine the endosperm structure by A. V. Simonov, T. A. Pshenichnikova

“…For the first time, a set of supersoft-grain lines with special properties of grain and flour was obtained on the genetic basis of three spring cultivars. They may be in demand for a wide range of end-uses, including both food and nonfood production purposes.…”
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Preliminary Results of the Kuznetsk Coal Basin Cover Deposits Radon Hazard Assessment by Timofey Leshukov, Konstantin Legoshchin, Elizaveta Baranova, Aleksey Larionov

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A method for siRNA-mediated knockdown of target genes in RA-induced neurogenesis using P19 cells by Hossein Khodadadi, Hiroaki Taniguchi

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Six events that shaped antibody approvals in oncology by Suman Paul, Suman Paul, Shibin Zhou, Shibin Zhou

“…Finally, we explore the development of ipilimumab, the first immune checkpoint-inhibiting antibody that activates the immune system to kill cancer cells, and the discovery that allowed the use of checkpoint inhibitors across all cancer types based on the presence of genetic markers. Revisiting these key events provides critical insights into the process of antibody development in oncology.…”
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Post-translational modifications as a key mechanism for herpes simplex virus type I evasion of host innate immunity by Yongxing Zhang, Junlei Xie, Ying Feng, Abdul Qadeer, Shanni Li, Xu Deng, Lipeng Zhu, Bo Kong, Zanxian Xia, Zanxian Xia

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Tissue-specific effects of benzo[a]pyrene and DDT on microRNA expression profile in female rats by D. S. Ushakov, T. S. Kalinina, A. S. Dorozhkova, V. Y. Ovchinnikov, L. F. Gulyaeva

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Supervised machine learning and genotype by trait biplot as promising approaches for selection of phytochemically enriched Rhus coriaria genotypes by Hamid Hatami Maleki, Reza Darvishzadeh, Ahmad Alijanpour, Yousef Seyfari

“…Climate change threats natural ecosystems and hence, evaluation of sumac's genetic diversity, identification of superior genotypes, and conservation of such materials is important. …”
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The finding of black currants from sect. <i>Eucoreosma</i> (Grossulariaceae) in the central part of southern Primorsky Territory, Russia by L. A. Fedina, M. A. Polezhaeva, D. R. Iunusova, M. N. Koldaeva, A. Sh. Sabitov

“…., and R. fontaneum Boczkarn. using morphological and molecular genetics techniques. Results and conclusion. A molecular genetics analysis of two chloroplast DNA fragments excluded any association of the discovered plants with R. nigrum or R. fontaneum. …”
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Elucidation of Nature of Gene Action and Estimation of Combining Ability Effects for Fruit Yield Improvement and Yield Attributing Traits in Brinjal Landraces by Neha Rajan, Sandip Debnath, Avijit kr. Dutta, Brijesh Pandey, Ajeet Kr. Singh, Ravindra Kumar Singh, Anjani Kumar Singh, Betty Nokobi Dugbakie

“…Genetic progress in quantitative traits can be improved by understanding how genes interact and estimating the consequences of combining abilities. …”
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Comprehensive analysis of the multi-rings mitochondrial genome of Populus tomentosa by Kai Gao, Ting Guo, Xinmin An

“…However, limited accessibility to the mitochondrial (mt) genome of P. tomentosa impedes phylogenetic and population genetic analyses and restricts functional gene research in Salicaceae family. …”
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Advanced Glycation End-Products and Hyperglycemia Increase Angiopoietin-2 Production by Impairing Angiopoietin-1-Tie-2 System by Alessandra Puddu, Roberta Sanguineti, Davide Maggi, Massimo Nicolò, Carlo E. Traverso, Renzo Cordera, Giorgio L. Viviani

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Harnessing multivariate insights coupled with susceptibility indices to reveal morpho-physiological and biochemical traits in heat tolerance of cotton by Tahira Luqman, Manzoor Hussain, Muhammad Kashif Riaz Khan

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Shallow-water mussels (Mytilus galloprovincialis) adapt to deep-sea environment through transcriptomic and metagenomic insights by Luyang Sun, Xiaolu Liu, Li Zhou, Hao Wang, Chao Lian, Zhaoshan Zhong, Minxiao Wang, Hao Chen, Chaolun Li

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Association of TNF-857C>T, TNFRSF1A36A>G, and TNFRSF1B676T>G Polymorphisms with Ischemic Stroke in a Greek Population by Sofia Markoula, Anthoula Chatzikyriakidou, Sotirios Giannopoulos, Kargiotis Odysseas, Sofia Markou, Konstantinos Vemmos, Ioannis Georgiou, Athanassios P. Kyritsis

“…Background. The role of genetic factors in the predisposition to develop ischemic stroke has been assessed by previous studies. …”
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Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice by Kamila Borowczyk, Jacek Wróblewski, Joanna Suliburska, Noriyuki Akahoshi, Isao Ishii, Hieronim Jakubowski

“…In the present work, we studied the prevalence and genetic determinants of keratin damage caused by homocysteinylation. …”
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