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A pathogenic COL7A1 variant highlights semi-dominant inheritance in dystrophic epidermolysis bullosa
Published 2025-02-01“…This study highlights the importance of considering semi-dominant inheritance models for dystrophic epidermolysis bullosa and other Mendelian diseases with an autosomal recessive mode of inheritance, as it can significantly impact diagnosis and genetic counseling.…”
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SPAGRM: effectively controlling for sample relatedness in large-scale genome-wide association studies of longitudinal traits
Published 2025-02-01“…A common strategy is to incorporate a random effect related to genetic relatedness matrix (GRM) into regression models. …”
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Properties of new polycationic bacteriochlorin photosensitizers: cytotoxicity and interaction with biofilms
Published 2024-09-01Get full text
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Metabolic changes before and after weaning in Dezhou donkey foals in relation to gut microbiota
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Enhanced myofibroblast differentiation of eMSCs in intrauterine adhesions
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Advancing pancreatic cancer research and therapeutics: the transformative role of organoid technology
Published 2025-01-01“…These three-dimensional cultures enable the proper recapitulation of the cellular architecture and genetic makeup of the original tumors, providing insights into the complex molecular and cellular dynamics at various stages of pancreatic ductal adenocarcinoma (PDAC). …”
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How does the mode of evolutionary divergence affect reproductive isolation?
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Oversized cells activate global proteasome-mediated protein degradation to maintain cell size homeostasis
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Insulin autoimmune syndrome in a 3-year-old boy: the youngest to date in China and a narrow review
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Developing mRNA lipid nanoparticle vaccine effective for cryptococcosis in a murine model
Published 2025-02-01Get full text
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