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3661
Study of the effect of the introduction of mitochondrial import determinants into the gRNA structure on the activity of the gRNA/SpCas9 complex in vitro
Published 2020-08-01“…All the characteristics and capabilities of the CRISPR/Cas9 system make it a promising tool in mitochondrial genetic engineering. In this article, we demonstrate for the first time that the modification of gRNA by integration of specific mitochondrial import determinants in the gRNA scaffold does not affect the activity of the gRNA/Cas9 complex in vitro.…”
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3662
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3663
CLARITY and Light-Sheet microscopy sample preparation in application to human cerebral organoids
Published 2022-01-01Get full text
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3664
Regulatory Role of the RUNX2 Transcription Factor in Lung Cancer Apoptosis
Published 2022-01-01Get full text
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3665
The molecular view of mechanical stress of brain cells, local translation, and neurodegenerative diseases
Published 2021-03-01Get full text
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3666
Microevolutionary differentiation of cereal tetraploid species by formation of recombinant genomes
Published 2016-08-01“…Dominance of regulatory genetic systems of the pivotal genome provides a high pairing level of homeologues from heterologous pairs in meiosis followed by intergenomic recombinations at the level of chromosome segments. …”
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3667
Effect of biogenic polyamines on sliding motility of mycobacteria in the presence of antibiotics
Published 2022-09-01Get full text
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3668
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3669
Autophagy: A New Avenue and Biochemical Mechanisms to Mitigate the Climate Change
Published 2024-01-01Get full text
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3670
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3671
Polygenic burden of short tandem repeat expansions promotes risk for Alzheimer’s disease
Published 2025-01-01“…However, most of the disease heritability has yet to be uncovered, suggesting that there is substantial genetic risk conferred by other forms of genetic variation. …”
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3672
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3673
VEIKIANTIS GENOMAS - VISUMINIS POŽYMIS: DABARTIES ŽVILGSNIS Į GENETIKĄ
Published 2003-01-01“…Every level can be characterized by the object of investigation and the criterion of object evaluation which in genetics is the feature. The five methodological levels of investigation could be distinguished during the course of genetics development: the organism - feature; the cell - feature; the chromosome - feature; DNA molecule - feature; nucleotide sequence - function. …”
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3674
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3675
Interspecific hybridization of potato: theoretical and applied aspects
Published 2017-03-01“…The common potato Solanum tuberosum is the fourth most important crop in the world and like many other cultivated plants is characterized by low level of genetic diversity. The most effective approach to broaden genetic diversity of breeding varieties is based on the introgression of genetic material of wild and cultivated species belonging to section Petota Dumort. of the genus Solanum L. …”
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3676
HMGB1 Box A gene therapy to alleviate bleomycin-induced pulmonary fibrosis in rats
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3677
Study on early inflorescence development in bread wheat (T. aestivum L.) lines with non-standard SCR-morphotype
Published 2017-04-01“…Wheat lines and forms with altered inflorescence morphology are important genetic resources for the study on the genetic mechanisms underlying plant developmental programs and inflorescence architecture; they are also important for practical use to increase productivity. …”
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3678
Site-selective dimethylation of flavonoids using fusion flavonoid O-methyltransferases
Published 2025-02-01Get full text
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3679
The role of the corticotropin-releasing hormone and its receptors in the regulation of stress response
Published 2021-04-01“…In this regard, the study of the participation of the CRH system and its receptors in negative effects on hormone-dependent systems, as well as the possibility of preventing them, is a promising task of modern physiological genetics. In this review, attention will be paid to the role of CRH in the regulation of response to stress, as well as to the involvement of extrahypothalamic CRH in pathophysiology and the correction of mental disorders.…”
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3680
Plant expression systems for production of recombinant pharmaceutically important proteins
Published 2018-01-01“…The prospects of creating plant (“edible”) vaccines based on genetically modified plants are discussed.…”
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